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Title: | Sugar-Lowering Drugs for Type 2 Diabetes Mellitus and Metabolic Syndrome-Review of Classical and New Compounds: Part-I | Authors: | Vieira, Raquel Souto, Selma B. Sánchez-López, Elena Machado, Ana López Severino, Patrícia Jose, Sajan Santini, Antonello Fortuna, A. García, Maria Luisa Silva, Amelia M. Souto, Eliana B. |
Keywords: | diabetes mellitus; metabolic syndrome; glucose-lowering agents; sugar-lowering oils; phytotherapy | Issue Date: | 10-Oct-2019 | Publisher: | MDPI | Project: | M-ERA-NET/0004/2015-PAIRED and UID/AGR/04033/2019 (CITAB), Institute of Nanoscience and Nanotechnology under the project ART(2018) |
Serial title, monograph or event: | Pharmaceuticals | Volume: | 12 | Issue: | 4 | Abstract: | Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia together with disturbances in the metabolism of carbohydrates, proteins and fat, which in general results from an insulin availability and need imbalance. In a great number of patients, marketed anti-glycemic agents have shown poor effectiveness in maintaining a long-term glycemic control, thus being associated with severe adverse effects and leading to an emerging interest in natural compounds (e.g., essential oils and other secondary plant metabolites, namely, flavonoid-rich compounds) as a novel approach for prevention, management and/or treatment of either non-insulin-dependent diabetes mellitus (T2DM, type 2 DM) and/or Metabolic Syndrome (MS). In this review, some of these promising glucose-lowering agents will be comprehensively discussed. | URI: | https://hdl.handle.net/10316/107210 | ISSN: | 1424-8247 | DOI: | 10.3390/ph12040152 | Rights: | openAccess |
Appears in Collections: | I&D CIBIT - Artigos em Revistas Internacionais FFUC- Artigos em Revistas Internacionais |
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