Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/105358
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Carvalho, Ana Luísa | - |
dc.contributor.author | Fernandes, Dominique | - |
dc.date.accessioned | 2023-02-20T10:46:47Z | - |
dc.date.available | 2023-02-20T10:46:47Z | - |
dc.date.issued | 2021-11 | - |
dc.identifier.issn | 1545-7885 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/105358 | - |
dc.description.abstract | Synaptic scaling allows neurons to adjust synaptic strength in response to chronic alterations in neuronal activity. A new study in PLOS Biology identifies a pathway that synergizes protein synthesis and degradation with remodeling of the microRNA (miRNA)-induced silencing complex (miRISC) to mediate synaptic scaling. | pt |
dc.language.iso | eng | pt |
dc.publisher | Public Library of Science | pt |
dc.relation | UIDB/04539/2020 | pt |
dc.relation | POCI-01-0145- FEDER-28541 | pt |
dc.relation | POCI-01-0145-FEDER-029452 | pt |
dc.relation | CENTRO-01-0145- FEDER-000008:BrainHealth2020 | pt |
dc.relation | “la Caixa” Foundation (ID 100010434) | pt |
dc.relation | FCT - LCF/PR/HP20/52300003 | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | pt |
dc.subject.mesh | Neurons | pt |
dc.subject.mesh | MicroRNAs | pt |
dc.subject.mesh | Protein Biosynthesis | pt |
dc.title | It takes two to tango: Concerted protein translation and degradation necessary for synaptic scaling | pt |
dc.type | article | - |
degois.publication.firstPage | e3001448 | pt |
degois.publication.issue | 11 | pt |
degois.publication.title | PLoS Biology | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.1371/journal.pbio.3001448 | pt |
degois.publication.volume | 19 | pt |
dc.date.embargo | 2021-11-01 | * |
uc.date.periodoEmbargo | 0 | pt |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
item.languageiso639-1 | en | - |
item.openairetype | article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | Com Texto completo | - |
crisitem.author.researchunit | CNC - Center for Neuroscience and Cell Biology | - |
crisitem.author.orcid | 0000-0001-8368-6666 | - |
Appears in Collections: | I&D CNC - Artigos em Revistas Internacionais IIIUC - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
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It-takes-two-to-tango-Concerted-protein-translation-and-degradation-necessary-for-synaptic-scalingPLoS-Biology.pdf | 1.56 MB | Adobe PDF | View/Open |
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