Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/105311
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ruaro, Barbara | - |
dc.contributor.author | Santiago, Tânia | - |
dc.contributor.author | Hughes, Michael | - |
dc.contributor.author | Lepri, Gemma | - |
dc.contributor.author | Poillucci, Gabriele | - |
dc.contributor.author | Baratella, Elisa | - |
dc.contributor.author | Salton, Francesco | - |
dc.contributor.author | Confalonieri, Marco | - |
dc.date.accessioned | 2023-02-16T11:00:08Z | - |
dc.date.available | 2023-02-16T11:00:08Z | - |
dc.date.issued | 2021 | - |
dc.identifier.issn | 1179-156X | pt |
dc.identifier.uri | https://hdl.handle.net/10316/105311 | - |
dc.description.abstract | Systemic sclerosis (SSc), an autoimmune connective tissue disease, characterized by skin fibrosis, increased dermal thickness and microvascular involvement. Fibroblasts and myofibroblasts deposit excessive amounts of collagenous and non-collagenous extracellular matrix components in the skin. This leads to microvascular abnormalities and Raynaud's phenomenon, with painful digital ulcers (DU) at the fingertips adding to patient discomfort. The skin involvement and severity in SSc was evaluated by the Modified Rodnan skin score (mRSS). Although high-frequency ultrasound (HUS) has been widely researched in the study of skin thickness and DU in SSc, its adoption into clinical practice is not yet common. However, novel insights into the still relatively unknown disease pathogenesis in SSc and its evaluation may be provided by HUS, including early (pre-clinical) skin involvement. It may also be useful in both the evaluation and follow-up of DU. Indeed, it is a non-invasive, safe, inexpensive and reproducible method able to assess not only SSc patients' cutaneous structural changes, but also their vascular system changes. Moreover, several recent studies have reported that elastosonography (ES) is of use when investigating skin involvement in systemic sclerosis. This review aims at providing information as to role HUS and ES play in research advancements and the clinical perspectives in the evaluation of skin thickness and DU in SSc patients. | pt |
dc.language.iso | eng | pt |
dc.publisher | Dove Medical Press | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | pt |
dc.subject | systemic sclerosis | pt |
dc.subject | ultrasound | pt |
dc.subject | elastosonography | pt |
dc.subject | skin | pt |
dc.subject | skin thickness | pt |
dc.subject | digital ulcers | pt |
dc.title | The Updated Role of Ultrasound in Assessing Dermatological Manifestations in Systemic Sclerosis | pt |
dc.type | article | - |
degois.publication.firstPage | 79 | pt |
degois.publication.lastPage | 91 | pt |
degois.publication.title | Open Access Rheumatology: Research and Reviews | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.2147/OARRR.S282612 | pt |
degois.publication.volume | 13 | pt |
dc.date.embargo | 2021-01-01 | * |
uc.date.periodoEmbargo | 0 | pt |
item.fulltext | Com Texto completo | - |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.openairetype | article | - |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
crisitem.author.orcid | 0000-0002-1562-4022 | - |
Appears in Collections: | FMUC Medicina - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
The-updated-role-of-ultrasound-in-assessing-dermatological-manifestations-in-systemic-sclerosisOpen-Access-Rheumatology-Research-and-Reviews.pdf | 695.82 kB | Adobe PDF | View/Open |
SCOPUSTM
Citations
5
checked on Jul 22, 2024
WEB OF SCIENCETM
Citations
5
checked on Jul 2, 2024
Page view(s)
39
checked on Jul 16, 2024
Download(s)
28
checked on Jul 16, 2024
Google ScholarTM
Check
Altmetric
Altmetric
This item is licensed under a Creative Commons License