Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/105191
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Fernandes, Liliana | - |
dc.contributor.author | Ribeiro, Henrique | - |
dc.contributor.author | Oliveira, Ana | - |
dc.contributor.author | Sanches Silva, Ana | - |
dc.contributor.author | Freitas, Andreia | - |
dc.contributor.author | Henriques, Mariana | - |
dc.contributor.author | Rodrigues, Maria Elisa | - |
dc.date.accessioned | 2023-02-08T10:58:33Z | - |
dc.date.available | 2023-02-08T10:58:33Z | - |
dc.date.issued | 2021-03 | - |
dc.identifier.issn | 2225-4110 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/105191 | - |
dc.description.abstract | Honey has been recognized worldwide for its antioxidant, anti-tumor, anti-inflammatory and antimicrobial properties. Among them, the antifungal properties associated to honey make it an attractive alternative treatment for Candida-associated infections, particularly for topical application to the mucous membranes and skin. In this sense, the main purpose of this work was to evaluate physicochemical properties of five Portuguese honeys and Manuka honey (an Australian honey with well recognized medical proprieties, used as control) and to evaluate the antifungal activity in Candida species planktonic and biofilm assays. Experimental procedure: Pollen analysis, pH determination, color, concentration of protein and methylglyoxal, conductivity, total phenolics and flavonoids, hydrogen peroxide concentration, and characterization by differential scanning calorimetry in honey samples were determined. Additionally, the effect of honeys on planktonic growth of Candida was initially evaluated by determination of the minimum inhibitory concentrations. Then, the same effect of those honeys was evaluated in biofilms, by Colony Forming Units enumeration. Results and conclusion: It has been shown that Portuguese heather (Erica cinereal) honey presented the most similar physicochemical properties to manuka honey (specially phenolic and flavonoids contents). The five Portuguese honeys under study, presented in general a potent activity against planktonic multiresistant yeast pathogens (several clinical isolates and reference strains of Candida species) and S. aureus and P. aeruginosa bacteria cultures. Additionally, it was also concluded that Portuguese heather honey (50% and 75% (w/v)) can also act as a good Candida species biofilm reducer, namely for C. tropicalis. | pt |
dc.language.iso | eng | pt |
dc.publisher | Elsevier | pt |
dc.relation | UIDBB/04469/2020020 | pt |
dc.relation | NORTE-01-0145-FEDER-000004 | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | pt |
dc.subject | Honey characterization | pt |
dc.subject | Honey therapy | pt |
dc.subject | Candida species | pt |
dc.subject | Candida biofilm | pt |
dc.subject | Natural antimicrobial approach | pt |
dc.title | Portuguese honeys as antimicrobial agents against Candida species | pt |
dc.type | article | - |
degois.publication.firstPage | 130 | pt |
degois.publication.lastPage | 136 | pt |
degois.publication.issue | 2 | pt |
degois.publication.title | Journal of Traditional and Complementary Medicine | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.1016/j.jtcme.2020.02.007 | pt |
degois.publication.volume | 11 | pt |
dc.date.embargo | 2021-03-01 | * |
uc.date.periodoEmbargo | 0 | pt |
item.grantfulltext | open | - |
item.fulltext | Com Texto completo | - |
item.openairetype | article | - |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
crisitem.author.researchunit | Language, Interpretation and Philosophy -LIF | - |
crisitem.author.orcid | 0000-0002-9272-940X | - |
crisitem.author.orcid | 0000-0003-3292-5473 | - |
Appears in Collections: | FFUC- Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
1-s2.0-S2225411019311186-main.pdf | 599.08 kB | Adobe PDF | View/Open |
SCOPUSTM
Citations
24
checked on Apr 29, 2024
WEB OF SCIENCETM
Citations
20
checked on May 2, 2024
Page view(s)
41
checked on May 7, 2024
Download(s)
30
checked on May 7, 2024
Google ScholarTM
Check
Altmetric
Altmetric
This item is licensed under a Creative Commons License