Please use this identifier to cite or link to this item: http://hdl.handle.net/10316/10472
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dc.contributor.authorMcLoughlin, D.-
dc.contributor.authorDias, R.-
dc.contributor.authorLindman, B.-
dc.contributor.authorCardenas, M.-
dc.contributor.authorNylander, T.-
dc.contributor.authorDawson, K.-
dc.contributor.authorMiguel, M.-
dc.contributor.authorLangevin, D.-
dc.date.accessioned2009-07-02T11:09:55Z-
dc.date.available2009-07-02T11:09:55Z-
dc.date.issued2005-03-01-
dc.identifier.citationLangmuir. 21:5 (2005) 1900-1907en_US
dc.identifier.issn0743-7463-
dc.identifier.urihttp://hdl.handle.net/10316/10472-
dc.description.abstractDNA interacts with insoluble monolayers made of cationic amphiphiles as well as with monolayers of zwitterionic lipids in the presence of divalent ions. Binding to dioctadecyldimethylammonium bromide (DODAB) or distearoyl-sn-glycero-3-phosphocholine (DSPC) monolayers in the presence of calcium is accompanied by monolayer expansion. For the positively charged DODAB monolayer, this causes a decrease of surface potential, while an increase is observed for the DSPC monolayers. Binding to dipalmitoyl-sn-glycero-3-phosphocholine preserves most of the liquid expanded−liquid condensed coexistence region. The liquid condensed domains adopt an elongated morphology in the presence of DNA, especially in the presence of calcium. The interaction of DNA with phospholipid monolayers is ion specific: the presence of calcium leads to a stronger interaction than magnesium and barium. These results were confirmed by bulk complexation studies.en_US
dc.language.isoengen_US
dc.publisherAmerican Chemical Societyen_US
dc.rightsopenAccesseng
dc.titleSurface Complexation of DNA with Insoluble Monolayers. Influence of Divalent Counterionsen_US
dc.typearticleen_US
dc.identifier.doi10.1021/la047700s-
uc.controloAutoridadeSim-
item.fulltextCom Texto completo-
item.languageiso639-1en-
item.grantfulltextopen-
crisitem.author.deptFaculty of Sciences and Technology-
crisitem.author.deptFaculty of Sciences and Technology-
crisitem.author.parentdeptUniversity of Coimbra-
crisitem.author.parentdeptUniversity of Coimbra-
crisitem.author.researchunitCQC - Coimbra Chemistry Centre-
crisitem.author.researchunitCQC - Coimbra Chemistry Centre-
crisitem.author.parentresearchunitFaculty of Sciences and Technology-
crisitem.author.parentresearchunitFaculty of Sciences and Technology-
crisitem.author.orcid0000-0002-7493-9112-
crisitem.author.orcid0000-0002-1601-5501-
Appears in Collections:FCTUC Química - Artigos em Revistas Internacionais
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