Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/10472
DC Field | Value | Language |
---|---|---|
dc.contributor.author | McLoughlin, D. | - |
dc.contributor.author | Dias, R. | - |
dc.contributor.author | Lindman, B. | - |
dc.contributor.author | Cardenas, M. | - |
dc.contributor.author | Nylander, T. | - |
dc.contributor.author | Dawson, K. | - |
dc.contributor.author | Miguel, M. | - |
dc.contributor.author | Langevin, D. | - |
dc.date.accessioned | 2009-07-02T11:09:55Z | - |
dc.date.available | 2009-07-02T11:09:55Z | - |
dc.date.issued | 2005-03-01 | - |
dc.identifier.citation | Langmuir. 21:5 (2005) 1900-1907 | en_US |
dc.identifier.issn | 0743-7463 | - |
dc.identifier.uri | https://hdl.handle.net/10316/10472 | - |
dc.description.abstract | DNA interacts with insoluble monolayers made of cationic amphiphiles as well as with monolayers of zwitterionic lipids in the presence of divalent ions. Binding to dioctadecyldimethylammonium bromide (DODAB) or distearoyl-sn-glycero-3-phosphocholine (DSPC) monolayers in the presence of calcium is accompanied by monolayer expansion. For the positively charged DODAB monolayer, this causes a decrease of surface potential, while an increase is observed for the DSPC monolayers. Binding to dipalmitoyl-sn-glycero-3-phosphocholine preserves most of the liquid expanded−liquid condensed coexistence region. The liquid condensed domains adopt an elongated morphology in the presence of DNA, especially in the presence of calcium. The interaction of DNA with phospholipid monolayers is ion specific: the presence of calcium leads to a stronger interaction than magnesium and barium. These results were confirmed by bulk complexation studies. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | American Chemical Society | en_US |
dc.rights | openAccess | eng |
dc.title | Surface Complexation of DNA with Insoluble Monolayers. Influence of Divalent Counterions | en_US |
dc.type | article | en_US |
dc.identifier.doi | 10.1021/la047700s | - |
uc.controloAutoridade | Sim | - |
item.fulltext | Com Texto completo | - |
item.grantfulltext | open | - |
item.languageiso639-1 | en | - |
item.cerifentitytype | Publications | - |
item.openairetype | article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.researchunit | CQC - Coimbra Chemistry Centre | - |
crisitem.author.researchunit | CQC - Coimbra Chemistry Centre | - |
crisitem.author.parentresearchunit | Faculty of Sciences and Technology | - |
crisitem.author.parentresearchunit | Faculty of Sciences and Technology | - |
crisitem.author.orcid | 0000-0002-7493-9112 | - |
crisitem.author.orcid | 0000-0002-1601-5501 | - |
Appears in Collections: | FCTUC Química - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Surface Complexation of DNA with Insoluble Monolayers.pdf | 670.08 kB | Adobe PDF | View/Open |
SCOPUSTM
Citations
62
checked on Oct 14, 2024
WEB OF SCIENCETM
Citations
1
62
checked on Oct 2, 2024
Page view(s)
344
checked on Oct 15, 2024
Download(s)
357
checked on Oct 15, 2024
Google ScholarTM
Check
Altmetric
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.