Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/103950
DC Field | Value | Language |
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dc.contributor.author | Silva, Amélia M. | - |
dc.contributor.author | Félix, Luís M | - |
dc.contributor.author | Teixeira, Isabel | - |
dc.contributor.author | Martins-Gomes, Carlos | - |
dc.contributor.author | Schäfer, Judith | - |
dc.contributor.author | Souto, Eliana B. | - |
dc.contributor.author | Santos, Dario J | - |
dc.contributor.author | Bunzel, Mirko | - |
dc.contributor.author | Nunes, Fernando M | - |
dc.date.accessioned | 2022-12-12T09:06:08Z | - |
dc.date.available | 2022-12-12T09:06:08Z | - |
dc.date.issued | 2021-12-30 | - |
dc.identifier.issn | 25901575 | pt |
dc.identifier.uri | https://hdl.handle.net/10316/103950 | - |
dc.description.abstract | Orange thyme (Thymus fragrantissimus) is becoming widely used in food as a condiment and herbal tea, nevertheless its chemical composition and potential bioactivities are largely unknown. Thus the objective of this work is to obtain a detailed phytochemical profile of T. fragrantissimus by exhaustive ethanolic extraction and by aqueous decoction mimicking its consumption. Extracts showed high content in rosmarinic acid, luteolin-O-hexuronide and eriodictyol-O-hexuronide; these were the main phenolic compounds present in orange thyme accounting for 85% of the total phenolic compounds. Orange thyme extracts presented high scavenging activity against nitric oxide and superoxide radicals. Both extracts presented significant inhibitory effect of tyrosinase activity and moderate anti-acetylcholinesterase activity. Both extracts showed a good in vitro anti-inflammatory activity and a weak anti-proliferative/cytotoxic activity against Caco-2 and HepG2 cell lines supporting its safe use. Orange thyme is a very good source of bioactive compounds with potential use in different food and nutraceutical industries. | pt |
dc.language.iso | eng | pt |
dc.publisher | Elsevier | pt |
dc.relation | INTERACT project–“Integrative Research in Environment, Agro-Chains and Technology”, no. NORTE- 01-0145-FEDER-000017, in its line of research entitled ISAC, cofinanced by the European Regional Development Fund (ERDF) through NORTE 2020 (North Regional Operational Program 2014/ 2020) | pt |
dc.relation | UIDB/04033/2020 | pt |
dc.relation | UIDB/00616/2020 | pt |
dc.relation | UIDP/ 00616/2020 | pt |
dc.relation | INTERACT - grant BI/UTAD/INTERACT/ISAC/203/2016 | pt |
dc.relation | INTERACT - grant BIM/UTAD/30/2018 | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | pt |
dc.subject | Orange thyme | pt |
dc.subject | Phenolic composition | pt |
dc.subject | Antioxidant activity | pt |
dc.subject | Anti-proliferative | pt |
dc.subject | Anti-inflammatory activity | pt |
dc.subject | Aqueous extract | pt |
dc.subject | Hydroethanolic extract | pt |
dc.subject | Radical scavenging activities | pt |
dc.title | Orange thyme: Phytochemical profiling, in vitro bioactivities of extracts and potential health benefits | pt |
dc.type | article | - |
degois.publication.firstPage | 100171 | pt |
degois.publication.title | Food Chemistry: X | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.1016/j.fochx.2021.100171 | pt |
degois.publication.volume | 12 | pt |
dc.date.embargo | 2021-12-30 | * |
uc.date.periodoEmbargo | 0 | pt |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
item.languageiso639-1 | en | - |
item.openairetype | article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | Com Texto completo | - |
crisitem.author.orcid | 0000-0002-9737-6017 | - |
Appears in Collections: | FFUC- Artigos em Revistas Internacionais |
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File | Description | Size | Format | |
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1-s2.0-S2590157521000596-main.pdf | 906.8 kB | Adobe PDF | View/Open |
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