Please use this identifier to cite or link to this item: https://hdl.handle.net/10316/103746
DC FieldValueLanguage
dc.contributor.authorFrancisco, Inês-
dc.contributor.authorPaula, Anabela Baptista-
dc.contributor.authorOliveiros, Bárbara-
dc.contributor.authorFernandes, Maria Helena-
dc.contributor.authorCarrilho, Eunice-
dc.contributor.authorMarto, Carlos Miguel-
dc.contributor.authorVale, Francisco-
dc.date.accessioned2022-11-24T11:13:34Z-
dc.date.available2022-11-24T11:13:34Z-
dc.date.issued2021-06-03-
dc.identifier.issn2306-5354pt
dc.identifier.urihttps://hdl.handle.net/10316/103746-
dc.description.abstract(1) Background: Alveolar bone defects or decreased alveolar bone height and width may have different causes, such as cleft palate. Regenerative procedures in oro-dental defects are challenging due to anatomical factors and the distinct cell populations involved. The iliac crest bone graft remains the gold-standard for cleft palate closure. However, tissue regeneration approaches have been employed and their outcome reviewed, but no conclusions have been made about which one is the gold-standard. (2) Methods: this umbrella review aims to critically appraise the effectiveness of the current approaches in bone defects regeneration in non-syndromic patients with cleft palate. A search was performed in PubMed, Cochrane Library, Scopus, Web of Science and EMBASE databases. (3) Results: Systematic reviews of randomized and non-randomized controlled trials with or without meta-analysis were included. Nine articles were included in the qualitative analysis and five in the quantitative one. The included studies quality was evaluated with AMSTAR2. (4) Conclusions: The use of new regenerative strategies, such as bone morphogenic protein 2, appears to provide similar results regarding bone volume, filling, and height to the standard technique with the iliac crest bone graft.pt
dc.language.isoengpt
dc.publisherMDPI AGpt
dc.rightsopenAccesspt
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt
dc.subjectautogenous graftpt
dc.subjectbiomaterialspt
dc.subjectcleft palatept
dc.subjectbone graftingpt
dc.subjectregenerativept
dc.titleRegenerative Strategies in Cleft Palate: An Umbrella Reviewpt
dc.typearticle-
degois.publication.firstPage76pt
degois.publication.issue6pt
degois.publication.titleBioengineeringpt
dc.peerreviewedyespt
dc.identifier.doi10.3390/bioengineering8060076pt
degois.publication.volume8pt
dc.date.embargo2021-06-03*
uc.date.periodoEmbargo0pt
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypearticle-
item.cerifentitytypePublications-
item.grantfulltextopen-
item.fulltextCom Texto completo-
item.languageiso639-1en-
crisitem.author.orcid0000-0002-3283-5104-
crisitem.author.orcid0000-0001-7836-8161-
crisitem.author.orcid0000-0002-5759-5557-
crisitem.author.orcid0000-0001-9269-5417-
crisitem.author.orcid0000-0003-2615-2929-
Appears in Collections:FMUC Medicina - Artigos em Revistas Internacionais
I&D ICBR - Artigos em Revistas Internacionais
I&D CIBB - Artigos em Revistas Internacionais
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