Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/102758
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Santos, Maria Sancha | - |
dc.contributor.author | Seiça, Raquel | - |
dc.contributor.author | Sena, Cristina | - |
dc.contributor.author | Nunes, Elsa | - |
dc.contributor.author | Peixoto, Francisco | - |
dc.contributor.author | Ferreira, Fernanda M. | - |
dc.date.accessioned | 2022-10-12T09:57:27Z | - |
dc.date.available | 2022-10-12T09:57:27Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 1734-154X | pt |
dc.identifier.issn | 0001-527X | pt |
dc.identifier.uri | https://hdl.handle.net/10316/102758 | - |
dc.description.abstract | Several chemical compounds found in plant products have proven to possess beneficial properties, being currently pointed out due to their pharmacological potential in type 2 diabetes mellitus complications. In this context, we studied the effect of Geranium robertianum L. (herb Robert) leaf decoctions in Goto–Kakizaki (GK) rats, a model of type 2 diabetes. Our results showed that oral administration of G. robertianum leaf decoctions over a period of four weeks lowered the plasma glucose levels in diabetic rats. Furthermore, the treatment with G. robertianum extracts improved liver mitochondrial respiratory parameters (state 3, state 4 and FCCP-stimulated respiration) and increased oxidative phosphorylation efficiency. | pt |
dc.language.iso | eng | pt |
dc.rights | openAccess | pt |
dc.rights.uri | http://creativecommons.org/licenses/by-sa/4.0/ | pt |
dc.subject | Goto–Kakizaki (GK) rats | pt |
dc.subject | type 2 diabetes mellitus | pt |
dc.subject | Geranium robertianum L., | pt |
dc.subject | Vaccinium myrtillus L. | pt |
dc.subject | herbal medicine | pt |
dc.subject | oxidative phosphorylation | pt |
dc.title | "MitoTea": Geranium robertianum L. decoctions decrease blood glucose levels and improve liver mitochondrial oxidative phosphorylation in diabetic Goto-Kakizaki rats | pt |
dc.type | article | - |
degois.publication.firstPage | 399 | pt |
degois.publication.lastPage | 402 | pt |
degois.publication.issue | 4 | pt |
degois.publication.title | Acta Biochimica Polonica | pt |
dc.peerreviewed | yes | pt |
dc.identifier.doi | 10.18388/abp.2010_2424 | pt |
degois.publication.volume | 57 | pt |
dc.date.embargo | 2010-01-01 | * |
uc.date.periodoEmbargo | 0 | pt |
item.fulltext | Com Texto completo | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.languageiso639-1 | en | - |
item.openairetype | article | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | open | - |
crisitem.author.researchunit | CNC - Center for Neuroscience and Cell Biology | - |
crisitem.author.researchunit | CNC - Center for Neuroscience and Cell Biology | - |
crisitem.author.orcid | 0000-0002-6881-9392 | - |
crisitem.author.orcid | 0000-0002-8378-0895 | - |
crisitem.author.orcid | 0000-0002-0889-2977 | - |
Appears in Collections: | I&D IBILI - Artigos em Revistas Internacionais I&D CNC - Artigos em Revistas Internacionais |
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This item is licensed under a Creative Commons License