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Title: | Probable initial pulmonary lymphangioleiomyomatosis and mediastinal lymphangioleiomyoma | Authors: | Pontes, M. Barbosa, C. Coelho, M. L. Carvalho, L. |
Keywords: | Mediastinal; Linfangioleiomioma; Linfangioleiomiomatose; Mediastinal; Lymphangioleiomyoma; Lymphangioleiomyoma- tosis | Issue Date: | 2014 | Serial title, monograph or event: | Revista Portuguesa de Pneumologia | Volume: | 20 | Issue: | 2 | Abstract: | A 68 year old woman was submitted to a mediastinal lymphangioleiomyoma resection found in a follow-up study of lower left lung resection due to bronchiectasis complicated by chylothorax. This led to a revaluation of the pulmonary specimen that revealed, in addition to inflammatory bronchiectasis, small spindle cell nodules in the lung parenchyma, similar to minute pulmonary meningothelial-like nodules, but with smooth muscle actin immunohistochemical positivity. The possibility of initial pulmonary development of lymphangioleiomyomatosis is discussed. Uma mulher de 68 anos foi submetida a uma ressecc¸ão de um linfoangioendotelioma mediastinal observado na monitorizac¸ão de uma lobectomia inferior esquerda devido a bronquiectasia, complicada por quilotórax. Isto levou a uma reavaliac¸ão do espécime pulmonar que revelou, além da bronquiectasia inflamatória, nódulos de pequenas células fusiformes no parênquima pulmonar, semelhantes a nódulos pulmonares de tipo meningotelial, mas com positividade imunohistoquímica para actina do músculo liso. A hipótese de desenvolvimento inicial de linfangioleiomiomatose pulmonar é discutida. |
URI: | https://hdl.handle.net/10316/102689 | ISSN: | 08732159 | DOI: | 10.1016/j.rppneu.2013.06.007 | Rights: | openAccess |
Appears in Collections: | FMUC Medicina - Artigos em Revistas Nacionais |
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1-s2.0-S0873215913001049-main.pdf | 3.3 MB | Adobe PDF | View/Open |
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