Carvalho, Luís A. E. Batista de
Claim profile
Loading...
2
0
20
0
false
Credit Name
Carvalho, Luís A. E. Batista de
Name
Carvalho, Luís Batista de
Variants
Carvalho, Luís A. E.
Carvalho, Luís A. E. Batista de
Carvalho, Luís A. E. Batista de
Unidade de I&D
Ciência ID
Researcher ID
Status
UC Researcher
Biography
Luís Alberto E. Batista de Carvalho (January 1961, Coimbra, Portugal) received his BSc (Hons) from the Department of Chemistry, Faculty of Science and Technology, University of Coimbra (1984) and his PhD in Chemistry, specialty Physical-Chemistry, from Faculty of Sciences, University of Lisbon (1993). He is currently associate professor at the Department of Chemistry, University of Coimbra and head of the “Molecular Physical-Chemistry” R&D Unit. Throughout his career he has developed several scientific research projects, in collaboration with national and international groups, in the areas of Medicinal Chemistry, Pharmaceutical Technology and Chemistry/Forensic Anthropology with special emphasis on the application of spectroscopic techniques: i) to the structural analysis of compounds of biological interest; ii) the development of new anti-cancer agents containing Pt and Pd (in particular, the determination of new therapeutic targets in order to optimize efficacy and minimize side effects and acquired resistance); iii) the study of drug/cell interactions in model systems (cancer cell lines) with a view to understanding the molecular mechanisms underlying cytotoxic activity; and iv) the analysis of changes induced by burning processes in human skeletons. He has preferably used vibrational spectroscopy, optical and with neutrons, including microRaman spectroscopy and FTIR with synchrotron radiation. Recently, and in conjunction with the aforementioned themes that he continues to develop, he started a research project that aims to apply vibrational spectroscopy techniques to the early diagnosis of cancer and rigorous determination of surgical margins (in the removal of malignant tumours). This subject involves not only methodological development but also the construction of a new Raman spectroscopy apparatus that increases the speed of diagnosis with a view to translate this technology to the clinics in the near future.
Loading...
3
0
20
0
false
Publications
(All)
Results 1-16 of 16 (Search time: 0.012 seconds).
| Issue Date | Title | Author(s) | Type | Access | |
|---|---|---|---|---|---|
| 1 | 2014 | An inelastic neutron scattering study of dietary phenolic acids | Marques, M. P. M. ; Carvalho, Luís A. E. Batista de ; Valero, Rosendo ; Machado, Nelson F. L. ; Parker, Stewart F. | article | openAccess |
| 2 | 2017 | Ancient burned Human Remains Probed by Neutron and Optical Vibrational Spectroscopy | Festa, G. ; Rickards, O. ; Martinez-Labarga, C. ; Martini, F. ; Marques, M. P. M. ; Carvalho, L. A. E. Batista de ; Gonçalves, D. ; Parker, S. F. ; Andreani, C. | conferenceObject | openAccess |
| 3 | 2018 | Biomaterials from human bone – probing organic fraction removal by chemical and enzymatic methods | Mamede, A. P. ; Vassalo, A. R. ; Cunha, E. ; Gonçalves, D. ; Parker, S. F. ; Carvalho, L. A. E. Batista de ; Marques, M. P. M. | article | openAccess |
| 4 | 1-Jan-2015 | Comment on “Assessment of new DFT methods for predicting vibrational spectra and structure of cisplatin: Which density functional should we choose for studying platinum(II) complexes?” [Spectrochim. Acta A125 (2014) 431–439] | Marques, Maria Paula M. ; Carvalho, Luís A. E. Batista de ; Parker, Stewart F. | article | openAccess |
| 5 | 1-Jan-2015 | Conformational insights and vibrational study of a promising anticancer agent: the role of the ligand in Pd(ii)–amine complexes | Fiuza, Sónia M. ; Amado, Ana M. ; Parker, Stewart F. ; Marques, Maria Paula M. ; Carvalho, Luís A. E. Batista de | article | openAccess |
| 6 | 2018 | Eating the bone! An enzymatic protocol aiming at bone’s organic matrix removal | Mamede, A. P. ; Vassalo, A. R. ; Gonçalves, David ; Parker, S. F. ; Carvalho, L. A. E. Batista de ; Marques, M. P. M. | conferenceObject | openAccess |
| 7 | 2018 | Heat-induced Bone Diagenesis Probed by Vibrational Spectroscopy | Marques, M. P. M. ; Mamede, A. P. ; Vassalo, A. R. ; Makhoul, C. ; Cunha, E. ; Gonçalves, D. ; Parker, S. F. ; Carvalho, L. A. E. Batista de | article | openAccess |
| 8 | 2011 | Inelastic Neutron Scattering Study of PtII Complexes Displaying Anticancer Properties | Carvalho, Luís A. E. Batista de ; Marques, M. Paula M. ; Martin, Christine ; Parker, Stewart F. ; Tomkinson, John | article | openAccess |
| 9 | 2018 | Le potentiel des groupes hydroxyles de la bioapatite pour discriminer des os brulés humains par spectroscopie vibrationelle | Gonçalves, David ; Mamede, Adriana P. ; Vassalo, Ana Rita ; Piga, Giampaolo ; Cunha, Eugénia ; Parker, Stewart F. ; Marques, Maria Paula Matos ; Carvalho, Luís A. E. Batista de | conferenceObject | openAccess |
| 10 | 21-Feb-2015 | A molecular view of cisplatin's mode of action: interplay with DNA bases and acquired resistance | Marques, M. P. M. ; Gianolio, Diego ; Cibin, Giannantonio ; Tomkinson, John ; Parker, Stewart F. ; Valero, Rosendo ; Pedro Lopes, R ; Carvalho, Luís A. E. Batista de | article | openAccess |
| 11 | 13-Jul-2016 | Osteometrics in burned human skeletal remains by neutron and optical vibrational spectroscopy | Marques, M. P. M. ; Gonçalves, D. ; Amarante, A. I. C. ; Makhoul, C. I. ; Parker, S. F. ; Carvalho, L. A. E. Batista de | article | openAccess |
| 12 | 2013 | Polymorphism in Cisplatin Anticancer Drug | Marques, M. Paula M. ; Valero, Rosendo ; Parker, Stewart F. ; Tomkinson, John ; Carvalho, Luís A. E. Batista de | article | openAccess |
| 13 | 2-Oct-2018 | Potential of Bioapatite Hydroxyls for Research on Archeological Burned Bone | Mamede, Adriana P. ; Vassalo, Ana R. ; Piga, Giampaolo ; Cunha, Eugénia ; Parker, Stewart F. ; Marques, M. Paula M. ; Carvalho, Luís A. E. Batista de ; Gonçalves, David | article | restrictedAccess |
| 14 | 2018 | Targeting the OH’s within Bone´s Bioapatite by Neutron and Optical Vibrational Spectroscopy | Mamede, A. P. ; Vassalo, A. R. ; Piga, G. ; Cunha, E. ; Parker, S. F. ; Marques, M. P. M. ; Carvalho, L. A. E. Batista de ; Gonçalves, D. | conferenceObject | openAccess |
| 15 | 2018 | Unravelling the mystery: FTIR-ATR and inelastic neutron scattering (INS) spectroscopies applied to the analysis of burned human skeletal remains | Vassalo, A. R. ; Mamede, P. ; Cunha, E. ; Parker, S. F. ; Marques, Maria Paula Matos ; Gonçalves, D. ; Carvalho, L. A. E. Batista de | conferenceObject | openAccess |
| 16 | 2018 | Widening the frontiers in Forensic Identification: probing burned human bones with neutron techniques | Mamede, A. P. ; Vassalo, A. R. ; Makhoul, C. ; Gonçalves, D. ; Parker, S. F. ; Kockelman, W ; Marques, Maria Paula Matos ; Carvalho, Luís A. E. Batista de | article | openAccess |