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This work was supported by Portuguese funds through FCT in the framework of a Ph.D. grant to SM (SFRH/BD/137802/2018). The project was funded by FCT through RESEARCH4COVID- 19 Special Programme, Project nº625. This research was partly supported by the project “Cancer Research on Therapy Resistance: From Basic Mechanisms to Novel Targets”—NORTE-01-0145- FEDER-000051-Consórcio POR-TO.CCC—Porto Comprehensive Cancer Center Raquel Seruca, supported by Norte Portugal Regional Operational Programme (NORTE 2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF) (NORTE- 01-0145-FEDER-072678).