This work was funded by FEDER funds through the Operational Programme Competitiveness Factors— COMPETE and by national funds by FCT—Foundation for Science and Technology under the projects UIDB/04564/2020 and UIDP/04564/2020 (M.M.S., J.C., R.T.), EXPL/ MED-ONC/0386/2021 and 2022.02665.PTDC (S.M., F.C., P.C., J.F., R.S.), and by Ministerio de Ciencia, Innovación y Universidades/FEDER (Spain/UE) through grant PID2022-141802NB-I00 (BASIC) (PG). J.F. is funded by the “FCT Scientific Employment Stimulus—Institutional Call” program (CEECINST/00056/2021). We acknowledge the American Association of Patients with Hereditary Gastric Cancer “No Stomach for Cancer” (J.F., R.S.), and the project “P.CCC: Centro Compreensivo de Cancro do Porto” - NORTE-01-0145-FEDER-072678, supported by Norte Portugal Regional Operational Programme (NORTE 2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF). We also acknowledge the support of the ALM i3S Scientific Platform, member of the PPBI (PPBI-POCI-01-0145- FEDER-022122). J.R.B. acknowledges the financial support the Brazilian National Council for Scientific and Technological Development (CNPq, proc. 304958/2022-0) and the Research Support Foundation of the State of Rio Grande do Sul (FAPERGS, TO 21/ 2551-0002024-5). M.M.S. thanks European Union’s Horizon 2020 Research and Innovation program under the Marie Skłodowska-Curie Actions Grant, Agreement no. 80113 (Scientia fellowship).

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This work was funded by FEDER funds through the Operational Programme Competitiveness Factors— COMPETE and by national funds by FCT—Foundation for Science and Technology under the projects UIDB/04564/2020 and UIDP/04564/2020 (M.M.S., J.C., R.T.), EXPL/ MED-ONC/0386/2021 and 2022.02665.PTDC (S.M., F.C., P.C., J.F., R.S.), and by Ministerio de Ciencia, Innovación y Universidades/FEDER (Spain/UE) through grant PID2022-141802NB-I00 (BASIC) (PG). J.F. is funded by the “FCT Scientific Employment Stimulus—Institutional Call” program (CEECINST/00056/2021). We acknowledge the American Association of Patients with Hereditary Gastric Cancer “No Stomach for Cancer” (J.F., R.S.), and the project “P.CCC: Centro Compreensivo de Cancro do Porto” - NORTE-01-0145-FEDER-072678, supported by Norte Portugal Regional Operational Programme (NORTE 2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF). We also acknowledge the support of the ALM i3S Scientific Platform, member of the PPBI (PPBI-POCI-01-0145- FEDER-022122). J.R.B. acknowledges the financial support the Brazilian National Council for Scientific and Technological Development (CNPq, proc. 304958/2022-0) and the Research Support Foundation of the State of Rio Grande do Sul (FAPERGS, TO 21/ 2551-0002024-5). M.M.S. thanks European Union’s Horizon 2020 Research and Innovation program under the Marie Skłodowska-Curie Actions Grant, Agreement no. 80113 (Scientia fellowship).

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18-Nov-2023The ECM and tissue architecture are major determinants of early invasion mediated by E-cadherin dysfunctionMelo, Soraia ; Guerrero, Pilar; Soares, Maurício Moreira ; Bordin, José Rafael; Carneiro, Fátima ; Carneiro, Patrícia; Dias, Maria Beatriz ; Carvalho, João ; Figueiredo, Joana; Seruca, Raquel ; Travasso, Rui D. M. articleopenAccess