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ThisworkwassupportedbygrantsfromGer- man ResearchFoundation(DFG-GO709/4-5),DZHK(German Centre forCardiovascularResearch),GermanFederalMinistryof Education andResearch(Acidox,Epiros),toAG.WorkintheAMR lab wassupportedbygrantsfromtheSpanishGovernment(PI12/ 00875)andfromtheFundaciónDomingoMartínez;AMRandPHA aresupportedbytheI3SNSandFPUprogramsoftheSpanish Government,respectively.WorkintheTKlabwassupportedby grants fromtheFinnishAcademyofSciences,theSigridJuselius Foundation, CIMO,andBiocenterOulu.Someoftheauthorswere supported bytheEuropeanCooperationinScienceandTechnology (COSTActionBM1203/EU‐ROS).