Browsing by Subject Pyrimidines
Results 1 to 10 of 10
| Issue Date | Title | Author(s) | Type | Access |
|---|---|---|---|---|
| 10-Jun-2015 | Adenosine A2AR blockade prevents neuroinflammation-induced death of retinal ganglion cells caused by elevated pressure | Madeira, Maria H. ; Elvas, Filipe ; Boia, Raquel ; Gonçalves, Francisco Q. ; Cunha, Rodrigo A. ; Ambrósio, A. Francisco ; Santiago, Ana Raquel | article | openAccess |
| 20-Aug-2012 | Blockade of adenosine A2A receptors prevents interleukin-1β-induced exacerbation of neuronal toxicity through a p38 mitogen-activated protein kinase pathway | Simões, Ana Patrícia ; Duarte, João A; Agasse, Fabienne ; Canas, Paula M. ; Tomé, Ângelo R. ; Agostinho, Paula ; Cunha, Rodrigo A. | article | openAccess |
| 2-Feb-2018 | Blockade of microglial adenosine A2A receptor impacts inflammatory mechanisms, reduces ARPE-19 cell dysfunction and prevents photoreceptor loss in vitro | Madeira, M. H. ; Rashid, K.; Ambrósio, Francisco ; Santiago, A. R. ; Langmann, T. | article | openAccess |
| 6-Nov-2021 | Dihydrofolate Reductase Inhibitors: The Pharmacophore as a Guide for Co-Crystal Screening | Baptista, João A. ; Rosado, Mário T. S. ; Castro, Ricardo A. E. ; Évora, António O. L. ; Maria, Teresa M. R. ; Silva, Manuela Ramos ; Canotilho, João ; Eusébio, M. Ermelinda S. | article | openAccess |
| 18-Feb-2016 | Drug screening on Hutchinson Gilford progeria pluripotent stem cells reveals aminopyrimidines as new modulators of farnesylation | Blondel, S.; Egesipe, A-L; Picardi, P.; Jaskowiak, A-L; Notarnicola, M.; Ragot, J.; Tournois, J.; Le Corf, A.; Brinon, B.; Poydenot, P.; Georges, P.; Navarro, C.; Pitrez, P. R. ; Ferreira, L. ; Bollot, G.; Bauvais, C.; Laustriat, D.; Mejat, A.; De Sandre-Giovannoli, A.; Levy, N.; Bifulco, M.; Peschanski, M.; Nissan, X. | article | openAccess |
| 17-Jun-2016 | Early synaptic deficits in the APP/PS1 mouse model of Alzheimer's disease involve neuronal adenosine A2A receptors | Silva, Sílvia Viana da ; Haberl, Matthias Georg; Zhang, Pei; Bethge, Philipp; Lemos, Cristina ; Gonçalves, Nélio ; Gorlewicz, Adam; Malezieux, Meryl; Gonçalves, Francisco Q. ; Grosjean, Noëlle; Blanchet, Christophe; Frick, Andreas; Nägerl, U Valentin; Cunha, Rodrigo A. ; Mulle, Christophe | article | openAccess |
| 2018 | Neuronal Adenosine A2A Receptors Are Critical Mediators of Neurodegeneration Triggered by Convulsions | Canas, Paula M. ; Porciúncula, Lisiane O. ; Simões, Ana Patrícia ; Augusto, Elisabete de Oliveira ; Silva, Henrique B. ; Machado, Nuno J. ; Gonçalves, Nélio ; Alfaro, Tiago M. ; Gonçalves, Francisco Q. ; Araújo, Inês M. ; Real, Joana I. ; Coelho, Joana E. ; Andrade, Geanne M. ; Almeida, Ramiro D. ; Chen, Jiang-Fan ; Köfalvi, Attila ; Agostinho, Paula ; Cunha, Rodrigo A. | article | openAccess |
| 7-Aug-2020 | Neuronal adenosine A2A receptors signal ergogenic effects of caffeine | Aguiar, Aderbal S. ; Speck, Ana Elisa ; Canas, Paula M. ; Cunha, Rodrigo A. | article | openAccess |
| Oct-2020 | Prolonged caffeine intake decreases alveolar bone damage induced by binge-like ethanol consumption in adolescent female rats | Maia, Cristiane; Pinheiro, Bruno Gonçalves; Soares da Silva, Carla Cristiane; Cunha, Rodrigo A. ; Souza-Monteiro, Deiweson; Martins Ferreira, Maria Karolina; Schmidt, Tuany Rafaeli; de Souza Balbinot, Gabriela; Collares, Fabrício Mezzomo; Martins, Manoela Domingues; Lima, Rafael Rodrigues | article | openAccess |
| 11-Jul-2020 | The Soluble Adenylyl Cyclase Inhibitor LRE1 Prevents Hepatic Ischemia/Reperfusion Damage Through Improvement of Mitochondrial Function | Teodoro, João S. ; Amorim, João A. ; Machado, Ivo F. ; Castela, Ana C. ; Steegborn, Clemens; Sinclair, David A; Rolo, Anabela P. ; Palmeira, Carlos M. | article | openAccess |