| Issue Date | Title | Author(s) | Type | Access |
1 | 2-May-2017 | MicroRNAs targeting Ataxin-3 mRNA in Machado-Joseph disease: from pathogenesis to therapy | Carmona, Vitor Manuel Martins | doctoralThesis | embargoedAccess |
2 | 31-Mar-2016 | Autophagy in the hypothalamus: role of Neuropeptide Y and impact on Synaptic Plasticity | Rocha, Mariana Botelho da | doctoralThesis | openAccess |
3 | 2022 | Cerebellar morphometric and spectroscopic biomarkers for Machado-Joseph Disease | Miranda, Catarina Oliveira ; Nobre, Rui Jorge ; Paiva, Vítor Hugo ; Duarte, João Valente ; Castelhano, João ; Petrella, Lorena Itati ; Sereno, José ; Santana, Magda ; Afonso, Sónia ; Januário, Cristina ; Castelo Branco, Miguel ; Almeida, Luís Pereira de | article | openAccess |
4 | 10-Feb-2016 | Neuropeptide Y gene transfer for neuroprotection in Machado-Joseph Disease | Neves, Joana Filipa Duarte das | doctoralThesis | embargoedAccess |
5 | 2015 | Evaluation of the potential anti-inflammatory and neuroprotective effect of a FAAH inhibitor in glaucome models | Martins, Joana Margarida Cardoso Serra | masterThesis | embargoedAccess |
6 | 2020 | Mesenchymal Stromal Cells' Therapy for Polyglutamine Disorders: Where Do We Stand and Where Should We Go? | Barros, Inês ; Marcelo, Adriana ; Silva, Teresa P. ; Barata, João ; Ramos, António David Rufino ; Almeida, Luís P. de ; Miranda, Catarina O. | article | openAccess |
7 | Sep-2013 | Caraterização do perfil genómico do carcinoma pulmonar | Portovedo, Sérgio Filipe de Jesus | masterThesis | openAccess |
8 | 7-Jul-2020 | Neurofilaments in spinocerebellar ataxia type 3: blood biomarkers at the preataxic and ataxic stage in humans and mice | Wilke, Carlo; Haas, Eva; Reetz, Kathrin; Faber, Jennifer; Garcia-Moreno, Hector; Santana, Magda M. ; van de Warrenburg, Bart; Hengel, Holger; Lima, Manuela ; Filla, Alessandro; Durr, Alexandra; Melegh, Bela; Masciullo, Marcella; Infante, Jon; Giunti, Paola; Neumann, Manuela; de Vries, Jeroen; Almeida, Luís Pereira de ; Rakowicz, Maria; Jacobi, Heike; Schüle, Rebecca; Kaeser, Stephan A.; Kuhle, Jens; Klockgether, Thomas; Schöls, Ludger; Barro, Christian; Hübener-Schmid, Jeannette; Synofzik, Matthis | article | openAccess |
9 | Jul-2015 | Síndrome de Down: caracterização e perspectivas futuras | Jorge, Maria Inês Lourenço | other | openAccess |
10 | 16-Feb-2016 | Non-viral silencing of Machado-Joseph disease through the systemic route | Conceição, Mariana Oliveira | doctoralThesis | embargoedAccess |
11 | 17-Feb-2017 | Delaying neurodegeneration through caloric restriction approaches: From mechanisms to molecular therapy | Santos, Janete Antónia da Cunha | doctoralThesis | embargoedAccess |
12 | Jan-2014 | Custo-efetividade da utilização de um teste farmacogenético para o Alopurinol em doentes portugueses diagnosticados com gota | Araújo, Maurício Alves | masterThesis | openAccess |
13 | 2001 | Neuroprotective Effect of a CNTF-Expressing Lentiviral Vector in the Quinolinic Acid Rat Model of Huntington's Disease | Almeida, L. Pereira de ; Zala, D. ; Aebischer, P. ; Déglon, N. | article | openAccess |
14 | 30-Jul-2014 | Relatório de estágio em farmácia comunitária | Nunes, Frederico de Brito | masterThesis | openAccess |
15 | 21-Feb-2003 | Lentiviral-basead gene delivery approaches for therapeutic and functional studies in Huntington's disease. | Almeida, Luís Fernando Morgado Pereira de | doctoralThesis | embargoedAccess |
16 | 8-Feb-2021 | Neuropeptide Y (NPY) intranasal delivery alleviates Machado-Joseph disease | Duarte-Neves, Joana ; Cavadas, Cláudia ; Almeida, Luís Pereira de | article | openAccess |
17 | 15-Jul-2008 | Striatal and nigral pathology in a lentiviral rat model of Machado-Joseph disease | Alves, Sandro ; Régulier, Etienne ; Nascimento-Ferreira, Isabel ; Hassig, Raymonde ; Dufour, Noelle ; Koeppen, Arnulf ; Carvalho, Ana Luísa ; Simões, Sérgio ; Lima, Maria C. Pedroso de ; Brouillet, Emmanuel ; Gould, Veronica Colomer ; Déglon, Nicole ; Almeida, Luís Pereira de | article | openAccess |
18 | 27-Jul-2012 | Calpain-mediated proteolysis of ataxin-3 in Machado-Joseph disease | Simões, Ana Teresa | doctoralThesis | embargoedAccess |
19 | 31-Aug-2020 | The blood-brain barrier is disrupted in Machado-Joseph disease/spinocerebellar ataxia type 3: evidence from transgenic mice and human post-mortem samples | Duarte Lobo, Diana; Nobre, Rui J. ; Miranda, Catarina Sofia Oliveira ; Pereira, Dina ; Castelhano, João ; Sereno, José ; Koeppen, Arnulf ; Castelo-Branco, Miguel ; Almeida, Luís Pereira de | article | openAccess |
20 | 2019 | Restoring brain cholesterol turnover improves autophagy and has therapeutic potential in mouse models of spinocerebellar ataxia | Nóbrega, Clévio David Rodrigues ; Mendonça, Liliana Simões ; Marcelo, Adriana Isabel do Vale ; Lamazière, Antonin; Tomé, Sandra Marisa Oliveira ; Despres, Gaetan; Matos, Carlos A; Mechmet, Fatich; Langui, Dominique; den Dunnen, Wilfred; Almeida, Luís Pereira de ; Cartier, Nathalie; Alves, Sandro José Paiva Fernandes | article | embargoedAccess |
21 | 2009 | Pharmacokinetic-pharmacodynamic interaction between Nebicapone and controlled-release levodopa/benserazide:a single-center, fase I, double-blind, randomized, placebo-controlled, four-way crossover study in healthy subjects | Nunes, Teresa ; Rocha, José F. ; Fernendes-Lopes, Carlos ; Costa, Raquel ; Torrão, Leonel ; Loureiro, Ana I. ; Falcão, Amílcar ; Vaz-da-Silva, Manuel ; Wright, Lyndon ; Almeida, Luís ; Soares-da-Silva, Patrício | article | openAccess |
22 | 27-Jul-2016 | Dissecting the pathogenesis of Machado-Joseph Disease in a new human disease model derived from induced pluripotent stem cells | Onofre, Isabel Maria dos Santos | doctoralThesis | embargoedAccess |
23 | Mar-2018 | Dipeptidyl peptidase IV (DPP-IV) inhibition prevents fibrosis in adipose tissue of obese mice | Marques, Ana Patrícia; Cunha-Santos, Janete; Leal, Helena; Sousa-Ferreira, Lígia ; Pereira de Almeida, Luís ; Cavadas, Cláudia ; Rosmaninho-Salgado, Joana | article | openAccess |
24 | 18-Jul-2019 | Relatórios de Estágio e Monografia intitulada “Biotecnologia Aplicada à Doença de Parkinson: Estratégias de Terapia Génica” | Ribeiro, André Filipe Santos | masterThesis | openAccess |
25 | 2012 | Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado–Joseph disease | Simões, Ana T. ; Gonçalves, Nélio ; Koeppen, Arnulf ; Déglon, Nicole ; Kügler, Sebastian ; Duarte, Carlos Bandeira ; Almeida, Luís Pereira de | article | openAccess |
26 | 5-Mar-2014 | Fluoxetine Induces Proliferation and Inhibits Differentiation of Hypothalamic Neuroprogenitor Cells In Vitro | Sousa-Ferreira, Lígia ; Aveleira, Célia ; Botelho, Mariana ; Álvaro, Ana Rita ; Almeida, Luís Pereira de ; Cavadas, Cláudia | article | openAccess |
27 | 17-Sep-2019 | Terapia Génica na Diabetes Mellitus tipo 1 | Branco, Marta Salvado Abreu Castelo | masterThesis | openAccess |
28 | 2005 | Effect of preventive and regressive isosorbide 5-mononitrate treatment on catecholamine levels in plasma, platelets, adrenals, left ventricle and aorta in cyclosporin A-induced hypertensive rats | Reis, Flávio ; Rocha, Luís ; Ponte, Luísa ; Alcobia, Teresa ; Almeida, Luís ; Costa-Almeida, Carlos ; Teixeira, Frederico | article | openAccess |
29 | 2004 | Long-term lentiviral-mediated expression of ciliary neurotrophic factor in the striatum of Huntington's disease transgenic mice | Zala, Diana ; Bensadoun, Jean-Charles ; Pereira de Almeida, Luis ; Leavitt, Blair R. ; Gutekunst, Claire-Anne ; Aebischer, Patrick ; Hayden, Michael R. ; Déglon, Nicole | article | openAccess |
30 | 2003 | Comparative study of GDNF delivery systems for the CNS: polymer rods, encapsulated cells, and lentiviral vectors | Bensadoun, Jean-Charles ; Pereira de Almeida, Luis ; Fine, Eric G. ; Tseng, Jack L. ; Déglon, Nicole ; Aebischer, Patrick | article | openAccess |
31 | 2015 | Estudo da potencial toxicidade do processo de silenciamento da ataxina 3 mutante humana mediado por shRNA lentiviral | Codêsso, José Miguel Antunes | masterThesis | openAccess |
32 | 2016 | Non-invasive viral-mediated gene therapy for Machado-Joseph disease | Saraiva, Joana Isabel Rajão | masterThesis | embargoedAccess |
33 | 18-Jul-2019 | Processos Biotecnológicos Aplicados ao Transplante de Órgãos | Jacinto, Sara Henrique Silvestre Neves | masterThesis | openAccess |
34 | 21-Oct-2021 | Gene editing technologies to Machado-Joseph disease | Lopes, Sara Isabel Monteiro | doctoralThesis | embargoedAccess |
35 | 15-Oct-2018 | Analytical Quality By Design To Characterize Inhalation Products | Gaspar, Joana Rita Mendes | masterThesis | openAccess |
36 | 3-Oct-2018 | Investigation of mutant ataxin-3 spreading in Machado-Joseph Disease | Moreira, Ricardo Gomes | masterThesis | embargoedAccess |
37 | 19-Oct-2018 | Ins2Akita mouse as a model of diabetic retinopathy: angiogenic and inflammatory characterization for selection of therapeutic targets | Silva, Maria Carolina Sousa | masterThesis | embargoedAccess |
38 | 2007 | siRNA delivery by a transferrin-associated lipid-based vector: a non-viral strategy to mediate gene silencing | Cardoso, A. L. C. ; Simões, S. ; Almeida, L. P. de ; Pelisek, J. ; Culmsee, C. ; Wagner, E. ; Lima, M. C. Pedroso de | article | openAccess |
39 | 2013 | Caffeine and adenosine A 2A receptor inactivation decrease striatal neuropathology in a lentiviral-based model of Machado–Joseph disease | Gonçalves, Nélio ; Simões, Ana T. ; Cunha, Rodrigo A. ; Almeida, Luís Pereira de | article | openAccess |
40 | 1-Jun-2011 | Effect of Food on the Pharmacokinetic Profile of Etamicastat (BIA 5-453) | Vaz-da-Silva, Manuel ; Nunes, Teresa ; Rocha, José F. ; Falcão, Amílcar ; Almeida, Luis ; Soares-da-Silva, Patricio | article | openAccess |
41 | 2003 | Application of non-local density functionals to clusters, surfaces and voids | Fiolhais, Carlos ; Almeida, Luís | article | openAccess |
42 | 25-Sep-2017 | Relatórios de Estágio e Monografia intitulada "Exossomas e outras vesículas extracelulares como biomarcadores" | Silva, Márcio Alexandre da Costa e | masterThesis | openAccess |
43 | 14-Sep-2017 | Relatórios de Estágio e Monografia intitulada “CRISPR/Cas9 na produção de modelos de doença do cérebro”. | Ferreira, Joana Catarina Martins | masterThesis | openAccess |
44 | 17-Oct-2017 | Machado-Joseph Disease: Understanding Epidemiologic and Clinical Features and a Potential New Therapeutic Entity | Silva, Patrick Joel da | masterThesis | embargoedAccess |
45 | 24-Feb-2017 | Défice Cognitivo Ligeiro e Doença de Alzheimer: as diferenças numa perspetiva proteómica | Freitas, Ana Karolina Seco das Neves | masterThesis | embargoedAccess |
46 | 12-Mar-2018 | Polymeric Micelles to improve Salinomycin delivery to cancer cells. | Kreutzer, Bruna | masterThesis | openAccess |
47 | 7-Jul-2021 | Living Proof of Activity of Extracellular Vesicles in the Central Nervous System | Mahjoum, Shadi; Rufino-Ramos, David; Almeida, Luís Pereira de ; Broekman, Marike L. D.; Breakefield, Xandra O.; van Solinge, Thomas S. | article | openAccess |
48 | 19-Sep-2017 | Relatórios de Estágio e Monografia intitulada “Exossomas – novos vetores para o transporte, entrega e tratamento de doenças do cérebro” | Silva, Maria Margarida Carvalho Vale da | masterThesis | openAccess |