Please use this identifier to cite or link to this item: http://hdl.handle.net/10316/95597
DC FieldValueLanguage
dc.contributor.authorDamas, Liliana Reis-
dc.contributor.authorRodrigues, Fábio M.S.-
dc.contributor.authorGonzalez, Andreia C.S.-
dc.contributor.authorCarrilho, Rui Miguel Barroso-
dc.contributor.authorPiñeiro Gomez, Marta-
dc.contributor.authorPereira, Maria Miguéns-
dc.date.accessioned2021-08-16T15:12:31Z-
dc.date.available2021-08-16T15:12:31Z-
dc.date.issued2020-
dc.identifier.issn0022328Xpt
dc.identifier.urihttp://hdl.handle.net/10316/95597-
dc.description.abstractThe sustainable synthesis of highly functionalised formylcarboxamide compounds with biological relevance is reported through a sequential aminocarbonylation/hydroformylation approach. The optimisation of palladium-catalysed aminocarbonylation of iodoaromatic substrates, using allylamine as nucleophile was first performed, with molybdenum hexacarbonyl as alternative CO source versus gaseous carbon monoxide. The combination of microwave irradiation with molybdenum hexacarbonyl allowed to selectively prepare a set of N-heterocyclic-based allylcarboxamides. Subsequent rhodium-catalysed hydroformylation of the allylcarboxamide intermediates led to the preparation of new pyridine, pyrazoline and chalcone derivatives containing both carboxamide and formyl moieties.pt
dc.language.isoengpt
dc.publisherElsevierpt
dc.relationinfo:eu-repo/grantAgreement/FCT/00313/2019/PTpt
dc.relationPTDC/QUI-OUT/27996/2017 (DUALPI)pt
dc.relationCENTRO-01-0145-FEDER-000014pt
dc.relationPD/BD/114340/2016pt
dc.rightsembargoedAccesspt
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/pt
dc.subjectSequential reactionspt
dc.subjectAminocarbonylationpt
dc.subjectHydroformylationpt
dc.subjectMicrowave synthesispt
dc.subjectN-heterocyclesChalconespt
dc.titleSequential catalytic carbonylation reactions for sustainable synthesis of biologically relevant entitiespt
dc.typearticle-
degois.publication.firstPage121417pt
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S0022328X20303193#!pt
dc.peerreviewedyespt
dc.identifier.doi10.1016/j.jorganchem.2020.121417pt
degois.publication.volume923pt
dc.date.embargo2021-12-31*
uc.date.periodoEmbargo730pt
item.fulltextCom Texto completo-
item.languageiso639-1en-
item.grantfulltextembargo_20211231-
crisitem.author.deptFaculty of Sciences and Technology-
crisitem.author.deptFaculty of Sciences and Technology-
crisitem.author.deptFaculty of Sciences and Technology-
crisitem.author.parentdeptUniversity of Coimbra-
crisitem.author.parentdeptUniversity of Coimbra-
crisitem.author.parentdeptUniversity of Coimbra-
crisitem.author.researchunitCQC - Coimbra Chemistry Centre-
crisitem.author.researchunitCQC - Coimbra Chemistry Centre-
crisitem.author.researchunitCQC - Coimbra Chemistry Centre-
crisitem.author.parentresearchunitFaculty of Sciences and Technology-
crisitem.author.parentresearchunitFaculty of Sciences and Technology-
crisitem.author.parentresearchunitFaculty of Sciences and Technology-
crisitem.author.orcid0000-0001-9923-359X-
crisitem.author.orcid0000-0002-7460-3758-
crisitem.author.orcid0000-0003-4958-7677-
Appears in Collections:I&D CQC - Artigos em Revistas Internacionais
Files in This Item:
File Description SizeFormat Login
1-s2.0-S0022328X20303193-main.pdf1.59 MBAdobe PDFEmbargo Access    Request a copy
Show simple item record

Page view(s)

32
checked on Oct 22, 2021

Download(s)

5
checked on Oct 22, 2021

Google ScholarTM

Check

Altmetric

Altmetric


This item is licensed under a Creative Commons License Creative Commons