Please use this identifier to cite or link to this item: http://hdl.handle.net/10316/80376
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dc.contributor.authorBueno, Cecilia Zorzi-
dc.contributor.authorDias, Ana Maria Antunes-
dc.contributor.authorSousa, Hermínio José Cipriano de-
dc.contributor.authorBraga, Mara Elga Medeiros-
dc.contributor.authorMoraes, Angela Maria-
dc.date.accessioned2018-07-23T14:15:18Z-
dc.date.available2018-07-23T14:15:18Z-
dc.date.issued2014-11-
dc.identifier.issn1873-0191pt
dc.identifier.urihttp://hdl.handle.net/10316/80376-
dc.description.abstractThis work addresses the development and characterization of porous chitosan-alginate based polyelectrolyte complexes, obtained by using two different proportions of the biocompatible surfactant Pluronic F68. These biomaterials are proposed for applications as biodegradable and biocompatible wound dressing and/or scaffolds. The results indicate that thickness, roughness, porosity and liquid uptake of the membranes increase with the amount of surfactant used, while their mechanical properties and stability in aqueous media decrease. Other important properties such as color and surface hydrophilicity (water contact angle) are not significantly altered or did not present a clear tendency of variation with the increase of the amount of surfactant added to the polyelectrolyte complexes, such as real density, average pore diameter, total pore volume and surface area. The prepared biomaterials were not cytotoxic to L929 cells. In conclusion, it is possible to tune the physicochemical properties of chitosan-alginate polyelectrolyte complexes, through the variation of the proportion of surfactant (Pluronic F68) added to the mixture, so as to enable the desired application of these biomaterials.pt
dc.language.isoengpt
dc.rightsopenAccesspt
dc.titleControl of the properties of porous chitosan-alginate membranes through the addition of different proportions of Pluronic F68pt
dc.typearticle-
degois.publication.firstPage117-25pt
degois.publication.lastPage125pt
dc.peerreviewedyespt
dc.identifier.doi10.1016/j.msec.2014.08.014pt
degois.publication.volume44pt
dc.date.embargo2014-11-01*
dc.date.periodoembargo0pt
dc.identifier.pmid25280687-
item.fulltextCom Texto completo-
item.languageiso639-1en-
item.grantfulltextopen-
crisitem.author.deptFaculty of Sciences and Technology-
crisitem.author.deptFaculty of Sciences and Technology-
crisitem.author.parentdeptUniversity of Coimbra-
crisitem.author.parentdeptUniversity of Coimbra-
crisitem.author.researchunitCIEPQPF – Chemical Process Engineering and Forest Products Research Centre-
crisitem.author.researchunitCIEPQPF – Chemical Process Engineering and Forest Products Research Centre-
crisitem.author.orcid0000-0002-2629-7805-
crisitem.author.orcid0000-0003-4142-4021-
Appears in Collections:I&D CIEPQPF - Artigos em Revistas Internacionais
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