Please use this identifier to cite or link to this item: http://hdl.handle.net/10316/5813
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dc.contributor.authorCanotilho, João-
dc.contributor.authorCosta, Felisbela S.-
dc.contributor.authorSousa, Adriano T.-
dc.contributor.authorRedinha, J. Simões-
dc.contributor.authorLeitão, M. Luísa P.-
dc.date.accessioned2008-09-26T17:42:13Z-
dc.date.available2008-09-26T17:42:13Z-
dc.date.issued2000en_US
dc.identifier.citationThermochimica Acta. 344:1-2 (2000) 9-13en_US
dc.identifier.urihttp://hdl.handle.net/10316/5813-
dc.description.abstractThe enthalpy of solution of terfenadine in ethanol/water mixtures, 0-20.5 wt.% of water was determined by calorimetry. A Sudden increase of 1-2 kJ mol-1 in the enthalpy at a concentration value around 0.01 mol kg-1 is observed. This step in the enthalpy is interpreted as due to solute n-mer aggregates formation. The solubility of terfenadine in the cosolvent systems used in the calorimetric studies was determined.en_US
dc.description.urihttp://www.sciencedirect.com/science/article/B6THV-3Y9X8C1-3/1/946cc8e5c8724eb5cab7f1c41b09d0f7en_US
dc.format.mimetypeaplication/PDFen
dc.language.isoengeng
dc.rightsopenAccesseng
dc.subjectCrystal designen_US
dc.subjectCrystallizationen_US
dc.subjectPolymorphismen_US
dc.subjectSolubilityen_US
dc.subjectSolute self-aggregationen_US
dc.subjectSolution enthalpyen_US
dc.subjectTerfenadineen_US
dc.titleEnthalpy of solution of terfenadine in ethanol/water mixturesen_US
dc.typearticleen_US
dc.identifier.doi10.1016/s0040-6031(99)00319-6-
item.fulltextCom Texto completo-
item.languageiso639-1en-
item.grantfulltextopen-
crisitem.author.deptFaculty of Pharmacy-
crisitem.author.researchunitCQC - Coimbra Chemistry Centre-
crisitem.author.parentresearchunitFaculty of Sciences and Technology-
crisitem.author.orcid0000-0001-6045-2330-
Appears in Collections:FFUC- Artigos em Revistas Internacionais
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