Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/47457
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Fialho, Renata | - |
dc.contributor.author | Pereira, Marco | - |
dc.contributor.author | Bucur, Mihaela | - |
dc.contributor.author | Fisher, Martin | - |
dc.contributor.author | Whale, Richard | - |
dc.contributor.author | Rusted, Jennifer | - |
dc.date.accessioned | 2018-02-05T11:36:43Z | - |
dc.date.available | 2018-02-05T11:36:43Z | - |
dc.date.issued | 2016 | - |
dc.identifier.citation | Fialho, R., Pereira, M., Bucur, M., Fisher, M., Whale, R., & Rusted, J. (2016). Cognitive impairment in HIV and HCV co-infected patients: A systematic review and meta-analysis. AIDS Care, 28(12), 1481-1494. doi:10.1080/09540121.2016.1191614 | por |
dc.identifier.uri | https://hdl.handle.net/10316/47457 | - |
dc.description.abstract | Cognitive impairment has been well documented in human immunodeficiency virus (HIV) and hepatitis C virus (HCV) mono-infections. However, in the context of HIV/HCV co-infection the research is more limited. The aim of this systematic review was to describe the characteristics of cognitive impairment in HIV/HCV co-infection and to examine the differences in cognitive performance between HIV/HCV and HIV and HCV mono-infected patients. Of the 437 records initially screened, 24 papers met the inclusion criteria and were included in the systematic review. Four studies were included in the meta-analysis. Most studies indicated that HIV/HCV co-infected patients had a higher level of cognitive impairment than HIV mono-infected patients. Meta-analysis also indicated that HIV mono-infected patients had a significantly lower global deficit score than co-infected patients. The results also indicated that co-infected patients were more likely to be impaired in information processing speed than HIV mono-infected patients. These findings can be challenged by biasing factors such as the small number of included studies, heterogeneity of the samples and a large diversity of methodological procedures. Future research with consistent and comprehensive neuropsychological batteries and covering a greater diversity of risk factors is needed, in order to clarify the effects of both viruses on cognitive function and the mechanisms that underlie these effects. Because cognitive impairments may pose significant challenges to medication adherence, quality of life and overall functioning, such knowledge may have important implications to the planning and implementation of effective interventions aimed at optimising the clinical management of these infections. | por |
dc.language.iso | eng | por |
dc.rights | openAccess | por |
dc.subject | Cognitive Dysfunction | por |
dc.subject | Coinfection | por |
dc.subject | Female | por |
dc.subject | HIV Infections | por |
dc.subject | Hepatitis C, Chronic | por |
dc.subject | Humans | por |
dc.subject | Male | por |
dc.subject | Mental Processes | por |
dc.title | Cognitive impairment in HIV and HCV co-infected patients: a systematic review and meta-analysis | por |
dc.type | article | por |
degois.publication.firstPage | 1481 | por |
degois.publication.lastPage | 1494 | por |
degois.publication.issue | 12 | por |
degois.publication.title | AIDS Care | por |
dc.relation.publisherversion | http://www.tandfonline.com/doi/full/10.1080/09540121.2016.1191614 | por |
dc.peerreviewed | yes | por |
dc.identifier.doi | 10.1080/09540121.2016.1191614 | - |
degois.publication.volume | 28 | por |
item.openairetype | article | - |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | open | - |
item.fulltext | Com Texto completo | - |
crisitem.author.researchunit | Center for Research in Neuropsychology and Cognitive Behavioral Intervention | - |
crisitem.author.orcid | 0000-0002-6086-2329 | - |
Appears in Collections: | FPCEUC - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
2016 Cognitive impairment in HIV HCV.pdf | 839.7 kB | Adobe PDF | View/Open |
SCOPUSTM
Citations
10
checked on Mar 25, 2024
WEB OF SCIENCETM
Citations
10
9
checked on Mar 2, 2024
Page view(s) 5
1,217
checked on Mar 26, 2024
Download(s) 50
495
checked on Mar 26, 2024
Google ScholarTM
Check
Altmetric
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.