Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/45111
DC Field | Value | Language |
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dc.contributor.author | Marques, Joana | - |
dc.contributor.author | Santos, Teresa M. | - |
dc.contributor.author | Marques, Maria Paula | - |
dc.contributor.author | Braga, Susana S. | - |
dc.date.accessioned | 2017-12-15T18:06:05Z | - |
dc.date.available | 2017-12-15T18:06:05Z | - |
dc.date.issued | 2009 | - |
dc.identifier.uri | https://hdl.handle.net/10316/45111 | - |
dc.description.abstract | The complex Ru([9]aneS(3))(gly)Cl (gly = glycine) was obtained from the reaction of the precursor Ru([9]aneS(3))dmsoCl(2) with glycine and encapsulated into native beta-CD, a hydroxypropylated derivative HPbetaCD, and the methylated cyclodextrins TRIMEB and CRYSMEB. All four inclusion compounds were obtained with a 1:1 host:guest stoichiometry and characterised in the solid-state by powder X-ray diffraction, thermogravimetric analysis (TGA), and (13)C{(1)H} CP/MAS NMR and FTIR spectroscopies. The cytostatic and antiproliferative activity of the complex Ru([9]aneS(3))(gly)Cl and its four CD inclusion compounds was tested on the human osteosarcoma MG-63 cell line and the results compared to the inhibitory effect exerted by the pure cyclodextrins. | por |
dc.language.iso | eng | por |
dc.rights | openAccess | por |
dc.subject | Antineoplastic Agents | por |
dc.subject | Bone Neoplasms | por |
dc.subject | Cell Line, Tumor | por |
dc.subject | Cell Proliferation | por |
dc.subject | Coordination Complexes | por |
dc.subject | Glycine | por |
dc.subject | Humans | por |
dc.subject | Osteosarcoma | por |
dc.subject | beta-Cyclodextrins | por |
dc.title | A glycine ruthenium trithiacyclononane complex and its molecular encapsulation using cyclodextrins | por |
dc.type | article | - |
degois.publication.firstPage | 9812 | por |
degois.publication.issue | 44 | por |
degois.publication.title | Dalton Transactions | por |
dc.peerreviewed | yes | por |
dc.identifier.doi | 10.1039/b915839a | por |
dc.identifier.doi | 10.1039/b915839a | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.openairetype | article | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | open | - |
item.fulltext | Com Texto completo | - |
item.languageiso639-1 | en | - |
crisitem.author.researchunit | QFM-UC – Molecular Physical-Chemistry R&D Unit | - |
crisitem.author.orcid | 0000-0002-7333-9158 | - |
crisitem.author.orcid | 0000-0002-8391-0055 | - |
Appears in Collections: | FCTUC Ciências da Vida - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
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Dalton_09_9812.pdf | 601.22 kB | Adobe PDF | View/Open |
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