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Title: Functionalization of nickel nanowires with a fluorophore aiming at new probes for multimodal bioanalysis
Authors: Pinheiro, Paula C. 
Sousa, Célia T. 
Araújo, João P. 
Guiomar, António J. 
Trindade, Tito 
Keywords: Aluminum oxide template; Nickel nanowires; Ferromagnetic; Surface functionalization; Fluorescence; Polyethyleneimine
Issue Date: 15-Nov-2013
Publisher: Elsevier
Citation: PINHEIRO, Paula C. [et al.] - Functionalization of nickel nanowires with a fluorophore aiming at new probes for multimodal bioanalysis. "Journal of Colloid and Interface Science". ISSN 0021-9797. Vol. 410 (2013) p. 21-26
Serial title, monograph or event: Journal of Colloid and Interface Science
Volume: 410
Abstract: This work reports research on the development of bimodal magnetic and fluorescent 1D nanoprobes. First, ferromagnetic nickel nanowires (NiNW) have been prepared by Ni electrodeposition in an anodic aluminum oxide (AAO) template. The highly ordered self-assembled AAO nanoporous templates were fabricated using a two-step anodization method of aluminum foil. The surface of the NiNW were then modified with polyethyleneimine (PEI) which was previously labeled with an organic dye (fluorescein isothiocyanate: FITC) via covalent bonding. The ensuing functionalized NiNW exhibited the characteristic green fluorescence of FITC and could be magnetically separated from aqueous solutions by using a NdFeB magnet. Finally, the interest of these bimodal NiNW as nanoprobes for in vitro cell separation and biolabeling was preliminary assessed in a proof of principle experiment that involved the attachment of biofunctionalized NiNW to blood cells.
ISSN: 0021-9797
DOI: 10.1016/j.jcis.2013.07.065
Rights: openAccess
Appears in Collections:I&D CIEPQPF - Artigos em Revistas Internacionais
FCTUC Ciências da Vida - Artigos em Revistas Internacionais

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