Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/12612
DC Field | Value | Language |
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dc.contributor.author | Urbano, M. | - |
dc.contributor.author | Rosa, A. | - |
dc.contributor.author | Gomes, D. | - |
dc.contributor.author | Camacho, E. | - |
dc.contributor.author | Calhau, C. A. | - |
dc.contributor.author | Leitão, M. | - |
dc.date.accessioned | 2010-02-26T09:38:14Z | - |
dc.date.available | 2010-02-26T09:38:14Z | - |
dc.date.issued | 2008 | - |
dc.identifier.citation | Revista Española de Enfermedades Digestivas. 100:8 (2008) 462-465 | en_US |
dc.identifier.issn | 1130-0108 | - |
dc.identifier.uri | https://hdl.handle.net/10316/12612 | - |
dc.description.abstract | OBJECTIVE: To evaluate the clinical usefulness of single-brush cytology performed at ERCP as initial method for detecting pancreatobiliary malignancy, ensuring a very close relationship between endoscopists, cytotechnicians, and cytopathologists. STUDY DESIGN: All 125 cytodiagnoses considered in this study correspond to the first brushing for each patient, collected by one of the three members of a fixed team of endoscopists in the presence of the same cytotechnician. Smears were fixed immediately with Merckofix spray, stained with Papanicolau, and analyzed by the same cytopathologist in a laboratory exclusively devoted to gastrointestinal cytopathology located at the endoscopy unit. RESULTS: Of 125 cytological diagnoses 94 were considered benign, 4 suspicious, and 27 malignant. These findings were compared to the final diagnosis of 45 malignant and 80 benign lesions obtained either by surgical pathology or after at least one year of clinical follow-up. The comparison yielded 30 true positives, 78 true negatives, 1 false positive and 16 false negative results, which corresponds to a sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of 65.2, 98.7, 96.8, 83, and 86.4%, respectively. CONCLUSION: Results seem to confirm the usefulness of an effective team approach to ERCP-directed brush cytology for the diagnosis of pancreatobiliary malignancy. However, sensitivity continues to be rather low | en_US |
dc.description.abstract | Objetivo: evaluar la utilidad clínica de la citología con cepillo único durante la CPRE como método inicial de detección de los cánceres pancreaticobiliares, garantizando una relación muy cer- cana entre endoscopistas, citotécnicos y citopatólogos. Diseño del estudio: los 125 citodiagnósticos considerados por este estudio corresponden al primer cepillado de cada pacien- te, realizado por uno de los tres miembros de un equipo fijo de endoscopistas en presencia del mismo citotécnico. Los frotis se fi- jaron inmediatamente con Merckofix® en aerosol, se tiñeron con Papanicolau y se analizaron por un mismo citopatólogo en un la- boratorio exclusivamente dedicado a la citopatología digestiva y situado en la unidad de endoscopia. Resultados: de los 125 diagnósticos citológicos, 94 se conside- raron benignos, 4 sospechosos y 27 malignos. Estos hallazgos se compararon con el diagnóstico final de 45 lesiones malignas y 80 le- siones benignas, obtenido mediante patología quirúrgica o con un año al menos de seguimiento clínico. La comparación arrojó 30 posi- tivos verdaderos, 78 negativos verdaderos, 1 positivo falso y 16 nega- tivos falsos, lo que corresponde a una sensibilidad, una especificidad, un valor pronóstico positivo, un valor pronóstico negativo y una pre- cisión del 65,2, el 98,7, el 96,8, el 83 y el 86,4%, respectivamente. Conclusión: los resultados parecen confirmar la utilidad de un abordaje en equipo eficaz de la citología con cepillo guiada por CPRE para el diagnóstico del cáncer pancreaticobiliar. Sin embar- go, la sensibilidad sigue siendo más bien baja | - |
dc.language.iso | eng | en_US |
dc.publisher | Grupo Aran | en_US |
dc.rights | openAccess | en_US |
dc.subject | Pancreatic malignancy | en_US |
dc.subject | Biliary malignancy | en_US |
dc.subject | Endoscopic retrograde cholangiopancreatography (ERCP) | en_US |
dc.subject | Brush cytology | en_US |
dc.subject | Diagnosis | en_US |
dc.title | Team approach to ERCP-directed single-brush cytology for the diagnosis of malignancy | en_US |
dc.type | article | en_US |
dc.identifier.doi | 10.4321/S1130-01082008000800003 | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.openairetype | article | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | open | - |
item.fulltext | Com Texto completo | - |
item.languageiso639-1 | en | - |
Appears in Collections: | FMUC Medicina - Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
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Team approach to ERCP.pdf | 248.72 kB | Adobe PDF | View/Open |
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