Please use this identifier to cite or link to this item: http://hdl.handle.net/10316/11254
DC FieldValueLanguage
dc.contributor.authorSimons, Kai-
dc.contributor.authorVaz, Winchil L. C.-
dc.date.accessioned2009-08-31T07:53:29Z-
dc.date.available2009-08-31T07:53:29Z-
dc.date.issued2004-06-
dc.identifier.citationAnnual review of biophysics and biomolecular structure. 33 (2004) 269-295en_US
dc.identifier.issn1056-8700-
dc.identifier.urihttp://hdl.handle.net/10316/11254-
dc.description.abstractViews of how cell membranes are organized are presently changing. The lipid bilayer that constitutes these membranes is no longer understood to be a homogeneous fluid. Instead, lipid assemblies, termed rafts, have been introduced to provide fluid platforms that segregate membrane components and dynamically compartmentalize membranes. These assemblies are thought to be composed mainly of sphingolipids and cholesterol in the outer leaflet, somehow connected to domains of unknown composition in the inner leaflet. Specific classes of proteins are associated with the rafts. This review critically analyzes what is known of phase behavior and liquid-liquid immiscibility in model systems and compares these data with what is known of domain formation in cell membranes.en_US
dc.language.isoengen_US
dc.publisherAnnual Reviewsen_US
dc.rightsopenAccesseng
dc.subjectSphingolipidsen_US
dc.subjectCholesterolen_US
dc.subjectPhase immiscibilityen_US
dc.subjectDetergent resistanceen_US
dc.subjectMembrane proteinsen_US
dc.titleModel systems, lipid rafts, and cell membranesen_US
dc.typearticleen_US
uc.controloAutoridadeSim-
item.grantfulltextopen-
item.fulltextCom Texto completo-
item.languageiso639-1en-
crisitem.author.deptFaculty of Sciences and Technology-
crisitem.author.parentdeptUniversity of Coimbra-
crisitem.author.researchunitCQC - Coimbra Chemistry Centre-
crisitem.author.parentresearchunitFaculty of Sciences and Technology-
crisitem.author.orcid0000-0002-3797-4330-
Appears in Collections:FCTUC Química - Artigos em Revistas Internacionais
Files in This Item:
File Description SizeFormat
Model systems, lipid rafts, and cell membranes.pdf355.04 kBAdobe PDFView/Open
Show simple item record

Page view(s) 50

439
checked on Sep 15, 2022

Download(s) 50

902
checked on Sep 15, 2022

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.