Please use this identifier to cite or link to this item:
https://hdl.handle.net/10316/101060
Title: | Social, environmental, and epidemiological aspects of leprosy occurrence in children in a hyperendemic region of Brazil | Authors: | da Silva, Fabiane Verônica Sousa, Gutembergue dos Santos Silva, Pãmela Rodrigues de Souza dos Santos, Emerson Soares Machado, R. B. F. Cortela, Denise da Costa Boamorte Ferreira, Silvana Margarida Benevides |
Keywords: | Leprosy; risk factor; contact; child population | Issue Date: | 2021 | Project: | National Council of Science and Technology development (CNPQ), Process number: 435239/2018-0, Call: UNIVERSAL 2018 | Serial title, monograph or event: | Leprosy Review | Volume: | 92 | Issue: | 4 | Abstract: | Introduction This is a case-control study aiming to analyze the predictive factors for the occurrence of leprosy in contacts under 15 years of age, considering aspects related to the socio-environmental and epidemiological conditions in a hyperendemic municipality. Methods Cases (n = 30) consisted of children with leprosy who were household contacts of adults notified with leprosy between 2016 and 2018. The controls (n = 128) comprised neighborhood contacts, without symptoms of leprosy, living within a radius of less than 100 m of the households with cases. Demographic, social, environmental, and epidemiological variables were analyzed. The software SPSS, version 20, was used. Odds Ratio and statistical significance level of p ≤ 0.05 were considered for association analysis. In the logistic regression analysis, the variables with results ≤20% were selected. Results After adjustments, the predictive variables for the occurrence of leprosy were age between 8 and 14 years (OR adjust = 4.5; 95% CI: 1.70; 12.18) and a family history of leprosy (OR adjust = 5.2; 95% CI: 1.95; 14.13). Conclusions The predictive factors studied may favor the occurrence of leprosy in those most vulnerable to this disease in the child population; strategies such as the use of immune chemoprophylaxis are recommended, especially in hyperendemic regions, such as the state of Mato Grosso. | URI: | https://hdl.handle.net/10316/101060 | ISSN: | 2162-8807 | DOI: | 10.47276/lr.92.4.398 | Rights: | openAccess |
Appears in Collections: | FDUC- Artigos em Revistas Internacionais |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Social-environmental-and-epidemiological-aspects-of-leprosy-occurrence-in-children-in-a-hyperendemic-region-of-BrazilLeprosy-Review.pdf | 64.2 kB | Adobe PDF | View/Open |
Page view(s)
43
checked on Mar 26, 2024
Download(s)
38
checked on Mar 26, 2024
Google ScholarTM
Check
Altmetric
Altmetric
This item is licensed under a Creative Commons License