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Title: Assessment of Human Pharmaceuticals in Drinking Water Catchments, Tap and Drinking Fountain Waters
Authors: Pereira, André 
Silva, Liliana 
Laranjeiro, Célia 
Pena, Angelina 
Keywords: environmental contaminants; pharmaceuticals; chemicals; Portugal; occurrence and fate
Issue Date: 2021
Project: UIDB/50006/2020 
Serial title, monograph or event: Applied Sciences (Switzerland)
Volume: 11
Issue: 15
Abstract: The occurrence of pharmaceuticals in water catchments and drinking waters raises potential risks to public health. Therefore, after addressing the major aquatic contamination pathway, the wastewater treatment plants (WWTPs), and, subsequently, surface waters, 18 human pharmaceuticals from 6 therapeutic groups (antibiotics, lipid regulators, selective serotonin reuptake inhibitors, non-steroidal anti-inflammatory drugs (NSAIDs) and hormones) were analyzed in drinking water catchments, tap and drinking fountain waters. This was performed by solid phase extraction (SPE) and liquid chromatography coupled with tandem mass detection (LC-MS/MS). The 97 samples analyzed were collected from 31 different sites in the center of Portugal. All samples presented concentrations below the method detection limits (MDLs) that ranged between 1.13 to 5.45 ng L1. The achieved results contributed to a better knowledge on the Portuguese and European context of drinking water, since there is a knowledge gap regarding this matrix. Comparing our data with other studies, published worldwide, we can observe that median concentrations of pharmaceuticals were reported in the low ng L1 levels, values close to our MDLs. Consequently, it is unlikely that, in light of the current knowledge, the presence of pharmaceuticals in drinking water presents a threat to human health.
ISSN: 2076-3417
DOI: 10.3390/app11157062
Rights: openAccess
Appears in Collections:FFUC- Artigos em Revistas Internacionais

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