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Credit Name
Cunha, Rodrigo A.
 
Name
Cunha, Rodrigo A.
 
Variants
Cunha, Rodrigo Antunes
Cunha, Rodrigo Pinto Santos Antunes
Cunha, Rodrigo Pinto Santos Antunes
 
 
 
 
Ciência ID
 
Scopus Author ID
 
Researcher ID
 
Status
UC Researcher
Biography
Rodrigo Antunes Cunha. Concluiu o(a) Doutoramento em Bioquímica em 1994/07 pelo(a) Universidade de Lisboa Faculdade de Ciências, Licenciatura em Bioquímica em 1989/06 pelo(a) Universidade de Lisboa Faculdade de Ciências e Licence em Clinical Research Associate em 1994/12 pelo(a) Rhône-Poulenc Rorer. É Professor Catedrático no(a) Universidade de Coimbra Faculdade de Medicina. Publicou 262 artigos em revistas especializadas. Possui 1 capítulo(s) de livros. Orientou 12 tese(s) de doutoramento e coorientou 25. Recebeu 9 prémio(s) e/ou homenagens. Atua na(s) área(s) de Ciências Médicas e da Saúde com ênfase em Medicina Básica com ênfase em Neurociências. No seu currículo Ciência Vitae os termos mais frequentes na contextualização da produção científica, tecnológica e artístico-cultural são: envelhecimento plasticidade; Alzheimer; memória; plasticidade sináptica; receptores; adenosina.
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Publications
(All)

Results 1-123 of 123 (Search time: 0.002 seconds).

Issue DateTitleAuthor(s)TypeAccess
12014Activation of microglia bolsters synapse formationCristovão, Gonçalo ; Pinto, Maria J. ; Cunha, Rodrigo A. ; Almeida, Ramiro D. ; Gomes, Catarina A. articleopenAccess
230-Jan-2013Activation of microglial cells triggers a release of brain-derived neurotrophic factor (BDNF) inducing their proliferation in an adenosine A2A receptor-dependent manner: A2A receptor blockade prevents BDNF release and proliferation of microgliaGomes, Catarina ; Ferreira, Raquel ; George, Jimmy ; Sanches, Rui; Rodrigues, Diana I. ; Gonçalves, Nélio ; Cunha, Rodrigo A. articleopenAccess
32008Adenosine A2A receptor antagonists exert motor and neuroprotective effects by distinct cellular mechanismsYu, Liqun ; Shen, Hai-Ying ; Coelho, Joana E. ; Araújo, Inês M. ; Huang, Qing-Yuan ; Day, Yuan-Ji ; Rebola, Nelson ; Canas, Paula M. ; Rapp, Erica Kirsten ; Ferrara, Jarrod ; Taylor, Darcie ; Müller, Christa E. ; Linden, Joel ; Cunha, Rodrigo A. ; Chen, Jiang-Fan articleopenAccess
42002Adenosine A2A receptor facilitation of hippocampal synaptic transmission is dependent on tonic A1 receptor inhibitionLopes, L. V. ; Cunha, R. A. ; Kull, B. ; Fredholm, B. B. ; Ribeiro, J. A. articleopenAccess
528-Jul-2023Adenosine A2A Receptor Up-Regulation Pre-Dates Deficits of Synaptic Plasticity and of Memory in Mice Exposed to Aβ1-42 to Model Early Alzheimer's DiseaseLopes, Cátia R. ; Silva, Antonio C. ; Silva, Henrique B. ; Canas, Paula M. ; Agostinho, Paula M. ; Cunha, Rodrigo A. ; Lopes, João Pedro articleopenAccess
62005Adenosine A2A receptors and metabotropic glutamate 5 receptors are co-localized and functionally interact in the hippocampus: a possible key mechanism in the modulation of N-methyl-d-aspartate effectsTebano, M. T. ; Martire, A. ; Rebola, N. ; Pepponi, R. ; Domenici, M. R. ; Grò, M. C. ; Schwarzschild, M. A. ; Chen, J. F. ; Cunha, R. A. ; Popoli, P. articleopenAccess
72021Adenosine A2A Receptors as Biomarkers of Brain DiseasesMoreira-de-Sá, Ana ; Lourenço, Vanessa S. ; Canas, Paula M. ; Cunha, Rodrigo A. articleopenAccess
812-Oct-2023Adenosine A2A receptors control generalization of contextual fear in ratsSimões, Ana P. ; Portes, Marina A.M. ; Lopes, Cátia R. ; Vanz, Felipe; Lourenço, Vanessa S. ; Pliássova, Anna ; Gaspar, Ingride L. ; Silva, Henrique B. ; Tomé, Ângelo R. ; Canas, Paula M. ; Prediger, Rui D.; Cunha, Rodrigo A. articleopenAccess
92018Adenosine A2A Receptors Control Glutamatergic Synaptic Plasticity in Fast Spiking Interneurons of the Prefrontal CortexKerkhofs, Amber; Canas, Paula M. ; Timmerman, A. J.; Heistek, Tim S.; Real, Joana I. ; Xavier, Carolina ; Cunha, Rodrigo A. ; Mansvelder, Huibert D.; Ferreira, Samira G. articleopenAccess
102005Adenosine A2A receptors control the extracellular levels of adenosine through modulation of nucleoside transporters activity in the rat hippocampusPinto-Duarte, António ; Coelho, Joana E. ; Cunha, Rodrigo A. ; Ribeiro, Joaquim Alexandre ; Sebastião, Ana M. articleopenAccess
112020Adenosine A2A receptors format long-term depression and memory strategies in a mouse model of Angelman syndromeMoreira-de-Sá, Ana ; Gonçalves, Francisco Q. ; Lopes, João P. ; Silva, Henrique B. ; Tomé, Ângelo R. ; Cunha, Rodrigo A. ; Canas, Paula articleopenAccess
122018Adenosine A2A Receptors in the Rat Prelimbic Medial Prefrontal Cortex Control Delay-Based Cost-Benefit Decision MakingLeffa, Douglas T; Pandolfo, Pablo; Gonçalves, Nélio ; Machado, Nuno J. ; de Souza, Carolina M; Real, Joana I. ; Silva, Antonio C. ; Silva, Henrique B. ; Köfalvi, Attila ; Cunha, Rodrigo A. ; Ferreira, Samira G. articleopenAccess
1321-Apr-2023Adenosine A2A Receptors Shut Down Adenosine A1 Receptor-Mediated Presynaptic Inhibition to Promote Implementation of Hippocampal Long-Term PotentiationLopes, Cátia R. ; Gonçalves, Francisco Q. ; Olaio, Simão ; Tomé, Ângelo R. ; Cunha, Rodrigo A. ; Lopes, João Pedro articleopenAccess
1410-Jun-2015Adenosine A2AR blockade prevents neuroinflammation-induced death of retinal ganglion cells caused by elevated pressureMadeira, Maria H. ; Elvas, Filipe ; Boia, Raquel ; Gonçalves, Francisco Q. ; Cunha, Rodrigo A. ; Ambrósio, A. Francisco ; Santiago, Ana Raquel articleopenAccess
152000Adenosine A2AReceptors Regulate the Extracellular Accumulation of Excitatory Amino Acids upon Metabolic Dysfunction in Chick Cultured Retinal CellsRego, Ana Cristina ; Agostinho, Paula ; Melo, Joana ; Cunha, Rodrigo A. ; Oliveira, Catarina R. articleopenAccess
162003Adenosine A3 receptors in the rat hippocampus: Lack of interaction with A1 receptorsLopes, Luísa V. ; Rebola, Nelson ; Costenla, Ana Rita ; Halldner, Linda ; Jacobson, Marlene A. ; Oliveira, Catarina R. ; Richardson, Peter J. ; Fredholm, Bertil B. ; Ribeiro, Joaquim A. ; Cunha, Rodrigo A. articleopenAccess
172013Adenosine A₂A receptors in striatal glutamatergic terminals and GABAergic neurons oppositely modulate psychostimulant action and DARPP-32 phosphorylationShen, Hai-Ying ; Canas, Paula M. ; Garcia-Sanz, Patricia; Lan, Jing-Quan; Boison, Detlev; Moratalla, Rosario; Cunha, Rodrigo A. ; Chen, Jiang-Fan articleopenAccess
182-Nov-2007Adenosine receptor heteromers and their integrative role in striatal functionFerré, Sergi ; Ciruela, Francisco; Quiroz, César; Luján, Rafael; Popoli, Patrizia; Cunha, Rodrigo A. ; Agnati, Luigi F; Fuxe, Kjell; Woods, Amina S; Lluis, Carme; Franco, RafaelarticleopenAccess
1911-Jan-2018Adenosine receptors in inflammatory lung diseasesAlfaro, Tiago Manuel Pombo doctoralThesisopenAccess
202007Anandamide and NADA bi-directionally modulate presynaptic Ca<sup>2+</sup> levels and transmitter release in the hippocampusKöfalvi, A. ; Pereira, M. F. ; Rebola, N. ; Rodrigues, R. J. ; Oliveira, C. R. ; Cunha, R. A. articleopenAccess
212018Anandamide Effects in a Streptozotocin-Induced Alzheimer's Disease-Like Sporadic Dementia in RatsMoreira-Silva, Daniel; Carrettiero, Daniel C.; Oliveira, Adriele S. A.; Rodrigues, Samanta; Dos Santos-Lopes, Joyce; Canas, Paula M. ; Cunha, Rodrigo A. ; Almeida, Maria C.; Ferreira, Tatiana L.articleopenAccess
2228-Sep-2017Antimicrobial peptide-gold nanoscale therapeutic formulation with high skin regenerative potentialComune, Michela ; Rai, Akhilesh ; Chereddy, Kiran K; Pinto, Sandra; Aday, Sezin; Ferreira, André F; Zonari, Alessandra ; Blersch, Josephine; Cunha, Rodrigo Pinto Antunes da ; Rodrigues, Ricardo; Lerma, Juan ; Simões, Pedro Nuno ; Préat, Veronique; Ferreira, Lino articleopenAccess
232021Astrocytes and Adenosine A2A Receptors: Active Players in Alzheimer's DiseaseLopes, Cátia R. ; Cunha, Rodrigo A. ; Agostinho, Paula articleopenAccess
24Jun-2016Astrocytic A2A receptors : novel targets to manage brain disordersHenriques, Vanessa Jorge masterThesisembargoedAccess
252015ATP as a multi-target danger signal in the brainRodrigues, Ricardo J. ; Tomé, Ângelo R. ; Cunha, Rodrigo A. articleopenAccess
262003ATP is released from nerve terminals and from activated muscle fibres on stimulation of the rat phrenic nerveSantos, D. A. ; Salgado, Audrey I. ; Cunha, Rodrigo A. articleopenAccess
272020ATP Signaling Controlling Dyskinesia Through P2X7 ReceptorsFonteles, Analu A.; Neves, Julliana C. S.; Menezes, Ana Paula F.; Pereira, Juliana F.; Silva, Ana Thais A.; Cunha, Rodrigo A. ; Andrade, Geanne M.articleopenAccess
2820-Jul-2020Avaliação do efeito do consumo de cafeína em doentes sob imunoterapia para cancro do pulmãoMarques, Alice Josefa FonsecamasterThesisembargoedAccess
292014Behavioral phenotyping of Parkin-deficient mice: looking for early preclinical features of Parkinson's diseaseRial, Daniel ; Castro, Adalberto A.; Machado, Nuno J. ; Garção, Pedro ; Gonçalves, Francisco Q. ; Silva, Henrique B. ; Tomé, Ângelo R. ; Köfalvi, Attila ; Corti, Olga; Raisman-Vozari, Rita; Cunha, Rodrigo A. ; Prediger, Rui D.articleopenAccess
302004Binding of adenosine receptor ligands to brain of adenosine receptor knock-out mice: evidence that CGS 21680 binds to A 1 receptors in hippocampusHalldner, Linda ; Lopes, Luisa V. ; Daré, Elisabetta ; Lindström, Karin ; Johansson, Björn ; Ledent, Catherine ; Cunha, Rodrigo A. ; Fredholm, Bertil B. articleopenAccess
3120-Aug-2012Blockade of adenosine A2A receptors prevents interleukin-1β-induced exacerbation of neuronal toxicity through a p38 mitogen-activated protein kinase pathwaySimões, Ana Patrícia ; Duarte, João A; Agasse, Fabienne ; Canas, Paula M. ; Tomé, Ângelo R. ; Agostinho, Paula ; Cunha, Rodrigo A. articleopenAccess
322007Blockade of adenosine A2A receptors prevents staurosporine-induced apoptosis of rat hippocampal neuronsSilva, Carla G. ; Porciúncula, Lisiane O. ; Canas, Paula M. ; Oliveira, Catarina R. ; Cunha, Rodrigo A. articleopenAccess
3327-Sep-2016Blunted dynamics of adenosine A2A receptors is associated with increased susceptibility to Candida albicans infection in the elderlyRodrigues, Lisa ; Miranda, Isabel M.; Andrade, Geanne M. ; Mota, Marta ; Cortes, Luísa ; Rodrigues, Acácio G.; Cunha, Rodrigo A. ; Gonçalves, Teresa articleopenAccess
3423-Feb-2022Brain Iron Deficiency Changes the Stoichiometry of Adenosine Receptor Subtypes in Cortico-Striatal Terminals: Implications for Restless Legs SyndromeRodrigues, Matilde S. ; Ferreira, Samira G. ; Quiroz, César; Earley, Christopher J; García-Borreguero, Diego; Cunha, Rodrigo A. ; Ciruela, Francisco ; Köfalvi, Attila ; Ferré, Sergi articleopenAccess
352013Caffeine and adenosine A 2A receptor inactivation decrease striatal neuropathology in a lentiviral-based model of Machado–Joseph diseaseGonçalves, Nélio ; Simões, Ana T. ; Cunha, Rodrigo A. ; Almeida, Luís Pereira de articleopenAccess
362012Caffeine consumption prevents diabetes-induced memory impairment and synaptotoxicity in the hippocampus of NONcZNO10/LTJ miceDuarte, João M. N. ; Agostinho, Paula M. ; Carvalho, Rui A. ; Cunha, Rodrigo A. articleopenAccess
372017Caffeine Controls Glutamatergic Synaptic Transmission and Pyramidal Neuron Excitability in Human NeocortexKerkhofs, Amber; Xavier, Ana C. ; da Silva, Beatriz S.; Canas, Paula M. ; Idema, Sander; Baayen, Johannes C.; Ferreira, Samira G. ; Cunha, Rodrigo A. ; Mansvelder, Huibert D.articleopenAccess
3810-May-2022Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and learning-dependent transcriptionPaiva, Isabel; Cellai, Lucrezia; Meriaux, Céline; Poncelet, Lauranne; Nebie, Ouada; Saliou, Jean-Michel; Lacoste, Anne-Sophie; Papegaey, Anthony; Drobecq, Hervé; Le Gras, Stéphanie; Schneider, Marion; Malik, Enas M; Müller, Christa E. ; Faivre, Emilie; Carvalho, Kevin ; Gomez-Murcia, Victoria; Vieau, Didier; Thiroux, Bryan; Eddarkaoui, Sabiha; Lebouvier, Thibaud; Schueller, Estelle; Tzeplaeff, Laura; Grgurina, Iris; Seguin, Jonathan; Stauber, Jonathan; Lopes, Luísa V. ; Buee, Luc; Buée-Scherrer, Valerie; Cunha, Rodrigo A. ; Ait-Belkacem, Rima; Sergeant, Nicolas; Annicotte, Jean-Sébastien; Boutillier, Anne-Laurence; Blum, DavidarticleopenAccess
392021Candida Extracellular Nucleotide Metabolism Promotes Neutrophils Extracellular Traps EscapeAfonso, Mariana; Mestre, Ana Rita ; Silva, Guilherme ; Almeida, Ana Catarina ; Cunha, Rodrigo A. ; Meyer-Fernandes, José Roberto; Gonçalves, Teresa ; Rodrigues, Lisa articleopenAccess
4029-Jan-2016Candida-host interaction: role of purine and adenosine A2A receptorsRodrigues, Lisa Catarina Oliveira doctoralThesisembargoedAccess
419-Oct-2014Characterization of ecto-5’-nucleotidase (CD73) in the brain – role in adenosine A2A receptor activationAugusto, Elisabete de Oliveira doctoralThesisembargoedAccess
422005Co-localization and functional interaction between adenosine A2A and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatumRodrigues, Ricardo J. ; Alfaro, Tiago M. ; Rebola, Nelson ; Oliveira, Catarina R. ; Cunha, Rodrigo A. articleopenAccess
432023Coffee consumption decreases the connectivity of the posterior Default Mode Network (DMN) at restPicó-Pérez, Maria; Magalhães, Ricardo; Esteves, Madalena; Vieira, Rita; Castanho, Teresa C.; Amorim, Liliana; Sousa, Mafalda ; Coelho, Ana; Moreira, Pedro S.; Cunha, Rodrigo A. ; Sousa, NunoarticleopenAccess
442009Control by adenosine A2A receptors of dopamine uptake in rat striatum and pre-frontal cortexSilveirinha, Vasco de Casimiro Lousada masterThesisopenAccess
4523-Jan-2020Control of glutamate release by complexes of adenosine and cannabinoid receptorsKöfalvi, Attila ; Moreno, Estefanía; Cordomí, Arnau; Cai, Ning-Sheng; Fernández-Dueñas, Victor; Ferreira, Samira G. ; Guixà-González, Ramón; Sánchez-Soto, Marta; Yano, Hideaki; Casadó-Anguera, Verònica; Cunha, Rodrigo A. ; Sebastião, Ana Maria; Ciruela, Francisco ; Pardo, Leonardo; Casadó, Vicent; Ferré, Sergi articleopenAccess
462021Crosstalk Between ATP-P2X7 and Adenosine A2A Receptors Controlling Neuroinflammation in Rats Subject to Repeated Restraint StressDias, Liliana ; Lopes, Cátia R. ; Gonçalves, Francisco Q. ; Nunes, Ana R. ; Pochmann, Daniela ; Machado, Nuno J. ; Tomé, Ângelo R. ; Agostinho, Paula ; Cunha, Rodrigo A. articleopenAccess
472008Different cellular sources and different roles of adenosine: A1 receptor-mediated inhibition through astrocytic-driven volume transmission and synapse-restricted A2A receptor-mediated facilitation of plasticityCunha, Rodrigo A. articleopenAccess
482007Differential glutamate-dependent and glutamate-independent adenosine A1 receptor-mediated modulation of dopamine release in different striatal compartmentsBorycz, Janusz ; Pereira, M. Fátima ; Melani, Alessia ; Rodrigues, Ricardo J. ; Köfalvi, Attila ; Panlilio, Leigh ; Pedata, Felicita ; Goldberg, Steven R. ; Cunha, Rodrigo A. ; Ferré, Sergi articleopenAccess
499-Apr-2023Downregulation of Sirtuin 1 Does Not Account for the Impaired Long-Term Potentiation in the Prefrontal Cortex of Female APPswe/PS1dE9 Mice Modelling Alzheimer's DiseaseLopes, Cátia R. ; Silva, Joana S; Santos, Joana ; Rodrigues, Matilde S. ; Madeira, Daniela ; Oliveira, Andreia ; Moreira-de-Sá, Ana ; Lourenço, Vanessa S. ; Gonçalves, Francisco Q. ; Silva, Henrique B. ; Simões, Ana Patrícia; Rolo, Anabela P. ; Canas, Paula M. ; Tomé, Ângelo R. ; Palmeira, Carlos M. ; Lopes, João Pedro ; Cunha, Rodrigo A. ; Agostinho, Paula M. ; Ferreira, Samira G. articleopenAccess
506-Jul-2005Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampusRodrigues, Ricardo J. ; Almeida, Teresa ; Richardson, Peter J. ; Oliveira, Catarina R. ; Cunha, Rodrigo A. articleopenAccess
5117-Jun-2016Early synaptic deficits in the APP/PS1 mouse model of Alzheimer's disease involve neuronal adenosine A2A receptorsSilva, Sílvia Viana da ; Haberl, Matthias Georg; Zhang, Pei; Bethge, Philipp; Lemos, Cristina ; Gonçalves, Nélio ; Gorlewicz, Adam; Malezieux, Meryl; Gonçalves, Francisco Q. ; Grosjean, Noëlle; Blanchet, Christophe; Frick, Andreas; Nägerl, U Valentin; Cunha, Rodrigo A. ; Mulle, Christophe articleopenAccess
522003Ecto-AMP Deaminase Blunts the ATP-Derived Adenosine A2A Receptor Facilitation of Acetylcholine Release at Rat Motor Nerve EndingsMagalhães-Cardoso, M. Teresa ; Pereira, M. Fátima ; Oliveira, Laura ; Ribeiro, J. A. ; Cunha, Rodrigo A. ; Correia-de-Sá, Paulo articleopenAccess
53Apr-2011Effect of caffeine consumption on the evolution of sarcoidosisCosta, Inês Sofia Marques Henriques Castanheira da masterThesisopenAccess
5413-Dec-2011Effect of Purines in the Developing Hippocampus - Consequences for the Establishment of Circuits Related to Learning and MemorySilva, Carla Sofia Gomes da doctoralThesisopenAccess
554-Jan-2023Effects of Chronic Caffeine Consumption on Synaptic Function, Metabolism and Adenosine Modulation in Different Brain AreasLopes, Cátia R. ; Oliveira, Andreia; Gaspar, Ingride L. ; Rodrigues, Matilde S. ; Santos, Joana ; Szabó, Eszter; Silva, Henrique B. ; Tomé, Ângelo R. ; Canas, Paula M. ; Agostinho, Paula M. ; Carvalho, Rui A. ; Cunha, Rodrigo A. ; Simões, Ana Patrícia ; Lopes, João Pedro ; Ferreira, Samira G. articleopenAccess
562018Elevated Pressure Changes the Purinergic System of Microglial CellsRodrigues-Neves, Ana C. ; Aires, Inês D. ; Vindeirinho, Joana R. ; Boia, Raquel ; Madeira, Maria H. ; Gonçalves, Francisco Q. ; Cunha, Rodrigo A. ; Santos, Paulo ; Ambrósio, Francisco ; Santiago, Ana R. articleopenAccess
57Aug-2003Enhanced adenosine A2A receptor facilitation of synaptic transmission in the hippocampus of aged ratsRebola, Nelson ; Sebastião, Ana M. ; Mendonça, Alexandre de ; Oliveira, Catarina R. ; Ribeiro, J. A. ; Cunha, Rodrigo A. articleopenAccess
5823-Jul-2013Exercise attenuates levodopa-induced dyskinesia in 6-hydroxydopamine-lesioned miceJr., A. S. Aguiar ; Moreira, E. L. G. ; Hoeller, A. A. ; Oliveira, P. A. ; Córdova, F. M. ; Glaser, V. ; Walz, R. ; Cunha, R. A. ; Leal, R. B. ; Latini, A. ; Prediger, R. D. S. articleopenAccess
59Nov-2019G protein-coupled receptor 37 (GPR37) emerges as an important modulator of adenosinergic transmission in the striatumMorato, Xavier; Cunha, Rodrigo A. ; Ciruela, Francisco articleopenAccess
601-Sep-2008GABA release by basket cells onto Purkinje cells, in rat cerebellar slices, is directly controlled by presynaptic purinergic receptors, modulating Ca2+ influxDonato, Roberta ; Rodrigues, Ricardo J. ; Takahashi, Michiko ; Tsai, Ming Chi ; Soto, David ; Miyagi, Kana ; Villafuertes, Rosa Gomez ; Cunha, Rodrigo A. ; Edwards, Frances A. articleopenAccess
6129-Nov-2013Gene transfer approaches to study the role of adenosine A2A receptors in Machado-Joseph diseaseGonçalves, Nélio da Mota doctoralThesisopenAccess
6220-Feb-2018Glutamate-induced and NMDA receptor-mediated neurodegeneration entails P2Y1 receptor activationSimões, Ana P. ; Silva, Carla G. ; Marques, Joana M. ; Pochmann, Daniela ; Porciúncula, Lisiane O. ; Ferreira, Sofia ; Oses, Jean P.; Beleza, Rui de O. ; Real, Joana I. ; Köfalvi, Attila ; Bahr, Ben A. ; Lerma, Juan ; Cunha, Rodrigo A. ; Rodrigues, Ricardo J. articleopenAccess
632006Heterodimeric adenosine receptors: a device to regulate neurotransmitter releaseCiruela, F. ; Ferré, S. ; Casadó, V. ; Cortés, A. ; Cunha, R. ; Lluis, C. ; Franco, R. articleopenAccess
642018Impact of Caffeine Consumption on Type 2 Diabetes-Induced Spatial Memory Impairment and Neurochemical Alterations in the HippocampusDuarte, João M. N. ; Skoug, Cecilia; Silva, Henrique B. ; Carvalho, Rui A. ; Gruetter, Rolf; Cunha, Rodrigo A. articleopenAccess
652007Increase of cannabinoid CB1 receptor density in the hippocampus of streptozotocin-induced diabetic ratsDuarte, João M. N. ; Nogueira, Célia ; Mackie, Ken ; Oliveira, Catarina R. ; Cunha, Rodrigo A. ; Köfalvi, Attila articleopenAccess
66Sep-2021Increased ATP release and CD73-mediated adenosine A2A receptor activation mediate convulsion-associated neuronal damage and hippocampal dysfunctionAugusto, Elisabete de Oliveira ; Gonçalves, Francisco Q.; Real, Joana E. ; Silva, Henrique B.; Pochmann, Daniela ; Silva, Tiago S.; Matos, Marco; Gonçalves, Nélio da Mota ; Tomé, Ângelo R. ; Chen, Jiang-Fan ; Canas, Paula M.; Cunha, Rodrigo A. articleopenAccess
67Mar-2023Increased ATP Release and Higher Impact of Adenosine A2A Receptors on Corticostriatal Plasticity in a Rat Model of Presymptomatic Parkinson's DiseaseGonçalves, Francisco Q. ; Matheus, Filipe C.; Silva, Henrique B. ; Real, Joana I. ; Rial, Daniel ; Rodrigues, Ricardo J. ; Oses, Jean-Pierre; Silva, Antonio C. ; Gonçalves, Nélio ; Prediger, Rui D.; Tomé, Ângelo R. ; Cunha, Rodrigo A. articleopenAccess
685-Apr-2023Increased Synaptic ATP Release and CD73-Mediated Formation of Extracellular Adenosine in the Control of Behavioral and Electrophysiological Modifications Caused by Chronic StressDias, Liliana ; Pochmann, Daniela ; Lemos, Cristina ; Silva, Henrique B. ; Real, Joana I. ; Gonçalves, Francisco Q. ; Rial, Daniel ; Gonçalves, Nélio ; Simões, Ana Patrícia ; Ferreira, Samira G. ; Agostinho, Paula M. ; Cunha, Rodrigo A. ; Tomé, Ângelo R. articleopenAccess
692006Interaction between P2X and nicotinic acetylcholine receptors in glutamate nerve terminals of the rat hippocampusRodrigues, Ricardo ; Almeida, Teresa ; Mendonça, Alexandre de ; Cunha, Rodrigo articleopenAccess
7015-Nov-2022Istradefylline protects from cisplatin-induced nephrotoxicity and peripheral neuropathy while preserving cisplatin antitumor effectsDewaeles, Edmone; Carvalho, Kévin; Fellah, Sandy; Sim, Jaewon; Boukrout, Nihad; Caillierez, Raphaelle; Ramakrishnan, Hariharan; Van der Hauwaert, Cynthia; Vijaya Shankara, Jhenkruthi; Martin, Nathalie; Massri, Noura; Launay, Agathe; Folger, Joseph K; Schutter, Clémentine de; Larrue, Romain; Loison, Ingrid; Goujon, Marine; Jung, Matthieu; Le Gras, Stéphanie; Gomez-Murcia, Victoria; Faivre, Emilie; Lemaire, Julie; Garat, Anne; Beauval, Nicolas; Maboudou, Patrice; Gnemmi, Viviane; Gibier, Jean-Baptiste; Buée, Luc; Abbadie, Corinne; Glowacki, Francois; Pottier, Nicolas; Perrais, Michael; Cunha, Rodrigo A. ; Annicotte, Jean-Sébastien; Laumet, Geoffroy; Blum, David; Cauffiez, ChristellearticleopenAccess
7118-Nov-2009Key modulatory role of presynaptic adenosine A2A receptors in cortical neurotransmission to the striatal direct pathwayQuiroz, César; Luján, Rafael; Uchigashima, Motokazu; Simões, Ana Patrícia ; Lerner, Talia N.; Borycz, Janusz ; Kachroo, Anil; Canas, Paula M. ; Orru, Marco; Schwarzschild, Michael A.; Rosin, Diane L.; Kreitzer, Anatol C.; Cunha, Rodrigo A. ; Watanabe, Masahiko; Ferré, Sergi articleopenAccess
725-Apr-2023Lateral septum adenosine A2A receptors control stress-induced depressive-like behaviors via signaling to the hypothalamus and habenulaWang, Muran; Li, Peijun; Li, Zewen; Silva, Beatriz S. da ; Zheng, Wu; Xiang, Zhenghua; He, Yan; Xu, Tao; Cordeiro, Cristina; Deng, Lu; Dai, Yuwei; Ye, Mengqian; Lin, Zhiqing; Zhou, Jianhong; Zhou, Xuzhao; Ye, Fenfen; Cunha, Rodrigo A. ; Chen, Jiang-Fan ; Guo, WeiarticleopenAccess
732005Long-term Effect of Convulsive Behavior on the Density of Adenosine A1 and A2A Receptors in the Rat Cerebral CortexRebola, Nelson ; Porciúncula, Lisiane O. ; Lopes, Luísa V. ; Oliveira, Catarina R. ; Soares-da-Silva, Patrício ; Cunha, Rodrigo A. articleopenAccess
742014Mitochondria in glutamatergic nerve terminals are selectively affected by exposure to Aβ1-42 modeling early Alzheimer's diseaseAmorim, João Filipe Alves masterThesisopenAccess
751-Sep-2008Modification of adenosine modulation of acetylcholine release in the hippocampus of aged ratsRodrigues, Ricardo J. ; Canas, Paula M. ; Lopes, Luísa V. ; Oliveira, Catarina R. ; Cunha, Rodrigo A. articleopenAccess
761-Sep-2008Modification upon aging of the density of presynaptic modulation systems in the hippocampusCanas, Paula M. ; Duarte, João M. N. ; Rodrigues, Ricardo J. ; Köfalvi, Attila ; Cunha, Rodrigo A. articleopenAccess
772009N-acyldopamines control striatal input terminals via novel ligand-gated cation channelsFerreira, Samira G. ; Lomaglio, Tonia ; Avelino, Antonio ; Cruz, Francisco ; Oliveira, Catarina R. ; Cunha, Rodrigo A. ; Köfalvi, Attila articleopenAccess
785-Apr-2017Neurobiology of the circadian clock: Metabolism control & Implications for Alzheimer´s diseaseSilva, Antonio Manuel Carvalho da doctoralThesisopenAccess
7918-May-2021Neuromodulation and neuroprotective effects of chlorogenic acids in excitatory synapses of mouse hippocampal slicesFernandes, Mara Yone D.; Dobrachinski, Fernando; Silva, Henrique B. ; Lopes, João Pedro ; Gonçalves, Francisco Q. ; Soares, Felix A A; Porciúncula, Lisiane O. ; Andrade, Geanne M; Cunha, Rodrigo A. ; Tomé, Ângelo R. articleopenAccess
8023-Sep-2007Neuromodulatory and neuroprotective roles of synaptic P2 receptorsRodrigues, Ricardo Jorge Alves doctoralThesisopenAccess
812018Neuronal Adenosine A2A Receptors Are Critical Mediators of Neurodegeneration Triggered by ConvulsionsCanas, Paula M. ; Porciúncula, Lisiane O. ; Simões, Ana Patrícia ; Augusto, Elisabete de Oliveira ; Silva, Henrique B. ; Machado, Nuno J. ; Gonçalves, Nélio ; Alfaro, Tiago M. ; Gonçalves, Francisco Q. ; Araújo, Inês M. ; Real, Joana I. ; Coelho, Joana E. ; Andrade, Geanne M. ; Almeida, Ramiro D. ; Chen, Jiang-Fan ; Köfalvi, Attila ; Agostinho, Paula ; Cunha, Rodrigo A. articleopenAccess
827-Aug-2020Neuronal adenosine A2A receptors signal ergogenic effects of caffeineAguiar, Aderbal S. ; Speck, Ana Elisa ; Canas, Paula M. ; Cunha, Rodrigo A. articleopenAccess
832005Neuroprotection by adenosine in the brain: From A1 receptor activation to A2A receptor blockadeCunha, Rodrigo articleopenAccess
8430-Nov-2009Neuroprotection by adenosine receptors in aged rats - role of neuroinflammationCanas, Paula Margarida Gomes doctoralThesisopenAccess
852014Nicotinic α7 receptor activation selectively potentiates the function of NMDA receptors in glutamatergic terminals of the nucleus accumbensZappettini, Stefania ; Grilli, Massimo ; Olivero, Guendalina; Chen, Jiayang ; Padolecchia, Cristina; Pittaluga, Anna ; Tomé, Ângelo R. ; Cunha, Rodrigo A. ; Marchi, Mario articleopenAccess
8619-Nov-2021NMR metabonomics applied to synaptosomes and slices to profile metabolic alterations in neurodegenerative and neuroprotection mechanismsOliveira, Andreia Filipa SimõesmasterThesisopenAccess
872014Overexpression of Adenosine A2A Receptors in Rats: Effects on Depression, Locomotion, and AnxietyCoelho, Joana E. ; Alves, Pedro; Canas, Paula M. ; Valadas, Jorge S.; Shmidt, Tatiana; Batalha, Vânia L.; Ferreira, Diana G.; Ribeiro, Joaquim A. ; Bader, Michael; Cunha, Rodrigo A. ; Couto, Frederico Simões do; Lopes, Luísa V. articleopenAccess
8820-Apr-2017O papel do sistema adenosinérgico em modelos animais de estresse crónico e depressãoMachado, Nuno Miguel de Jesus doctoralThesisopenAccess
8919-Nov-2013O papel dos receptores de adenosina A2A em astrócitos - implicações para a actividade glutamatérgicaMatos, Marco António Paisana doctoralThesisopenAccess
9026-Mar-2021PATHOPHYSIOLOGICAL ROLE OF ADENOSINERGIC MODULATION WITHIN THE BASOLATERAL COMPLEX OF THE AMYGDALAPliassova, Anna VladimirovnadoctoralThesisembargoedAccess
9119-Dec-2014Pathophysiology of Hippocampal CA3 Neurons in the APP/PS1 Mouse Model of Alzheimer’s DiseaseSilva, Sílvia Margarida Viana da doctoralThesisembargoedAccess
922000Pertussis toxin prevents presynaptic inhibition by kainate receptors of rat hippocampal [3H]GABA releaseCunha, Rodrigo A. ; Malva, João O. ; Ribeiro, J. A. articleopenAccess
9316-May-2018Physio-pathological role of ecto-5’-nucleotidase – a new target for neuroprotectionGonçalves, Francisco Manuel QueirozdoctoralThesisopenAccess
942008Potential therapeutic interest of adenosine A2A receptors in psychiatric disordersCunha, Rodrigo A. ; Ferré, Sergi ; Vaugeois, Jean-Marie ; Chen, Jiang-Fan articleopenAccess
952014Presynaptic A2A adenosine receptors dampen CB1 cannabinoid receptor-mediated inhibition of corticostriatal glutamatergic transmissionFerreira, S. G. ; Gonçalves, F. Q. ; Marques, J. M. ; Tomé, Â. R. ; Rodrigues, R. J. ; Nunes-Correia, I. ; Ledent, C. ; Harkany, T. ; Venance, L. ; Cunha, R. A. ; Köfalvi, A. articleembargoedAccess
962012Presynaptic A₂A adenosine receptors control CB₁ cannabinoid receptor-mediated effects at the corticostriatal nerve terminalsFerreira, Samira Cardoso Lopes doctoralThesisclosedAccess
972004Presynaptic kainate receptors modulating glutamatergic transmission in the rat hippocampus are inhibited by arachidonic acidCunha, Rodrigo A. ; Ribeiro, J. A. ; Malva, João O. articleopenAccess
982003Presynaptic Modulation Controlling Neuronal Excitability and Epileptogenesis: Role of Kainate, Adenosine and Neuropeptide Y ReceptorsMalva, João O. ; Silva, Ana P. ; Cunha, Rodrigo A. articleopenAccess
99Oct-2020Prolonged caffeine intake decreases alveolar bone damage induced by binge-like ethanol consumption in adolescent female ratsMaia, Cristiane; Pinheiro, Bruno Gonçalves; Soares da Silva, Carla Cristiane; Cunha, Rodrigo A. ; Souza-Monteiro, Deiweson; Martins Ferreira, Maria Karolina; Schmidt, Tuany Rafaeli; de Souza Balbinot, Gabriela; Collares, Fabrício Mezzomo; Martins, Manoela Domingues; Lima, Rafael RodriguesarticleopenAccess
100Apr-2014Prolonged nicotine exposure down-regulates presynaptic NMDA receptors in dopaminergic terminals of the rat nucleus accumbensSalamone, Alessia ; Zappettini, Stefania ; Grilli, Massimo ; Guendalina, Paula ; Tomé, Ângelo R. ; Chen, Jiayang ; Pittaluga, Anna ; Cunha, Rodrigo A. ; Marchi, Mario articleopenAccess
1012012Pulmonary extracellular adenosine triphosphate in hypersensitivity pneumonitis and sarcoidosis : a preliminary studyRosa, Beatriz Simões de Carvalho Rama masterThesisopenAccess
10227-Apr-2012Purinergic control of neuroinflammation and neuroprotection by the blockade of P2 receptors under excitotoxic conditions in the hippocampusSimões, Ana Patrícia Figueiredo Rocha doctoralThesisopenAccess
1032003Purinergic P2 receptors trigger adenosine release leading to adenosine A2A receptor activation and facilitation of long-term potentiation in rat hippocampal slicesAlmeida, T. ; Rodrigues, R. J. ; Mendonça, A. de ; Ribeiro, J. A. ; Cunha, R. A. articleopenAccess
10421-Jan-2016Purines control neuron-glia interaction during neuroinflammationGeorge, Jimmy doctoralThesisopenAccess
1052005Recovery of hippocampal metabolism from hypoxia - role of the adenosine A1 receptorDuarte, J. M. ; Cunha, R. A. ; Carvalho, R. A. conferenceObjectopenAccess
1062012Regulation of Mitochondrial Function in Ischemia/Reperfusion: Looking for Therapeutic Strategies in Fatty LiversVarela, Ana Teresa Inácio Ferreira doctoralThesisopenAccess
1072001Regulation of the Ecto-Nucleotidase Pathway in Rat Hippocampal Nerve TerminalsCunha, R. A. articleopenAccess
1082014Role of microglia adenosine A(2A) receptors in retinal and brain neurodegenerative diseasesSantiago, Ana R. ; Baptista, Filipa I. ; Santos, Paulo ; Cristovão, Gonçalo ; Ambrósio, A. Francisco ; Cunha, Rodrigo A. ; Gomes, Catarina A. articleopenAccess
109Apr-2019Signaling by adenosine receptors-Homeostatic or allostatic control?Cunha, Rodrigo A. articleopenAccess
1102022Simultaneous Alteration of the Circadian Variation of Memory, Hippocampal Synaptic Plasticity, and Metabolism in a Triple Transgenic Mouse Model of Alzheimer's DiseaseCarvalho da Silva, António M ; Lemos, Cristina ; Silva, Henrique Bernardo ; Ferreira, Ildete L. ; Tomé, Ângelo R.; Rego, A. Cristina ; Cunha, Rodrigo A. articleopenAccess
11110-Oct-2013Spatial memory impairments in a prediabetic rat modelSoares, E. ; Prediger, R. D. ; Nunes, S. ; Castro, A. A. ; Viana, S .D. ; Lemos, C. ; Souza, C. M. De ; Agostinho, P. ; Cunha, R. A. ; Carvalho, E. ; Ribeiro, C. A. Fontes ; Reis, F. ; Pereira, F. C. articleopenAccess
1122003Subcellular localization of adenosine A1 receptors in nerve terminals and synapses of the rat hippocampusRebola, Nelson ; Pinheiro, Paulo C. ; Oliveira, Catarina R. ; Malva, João O. ; Cunha, Rodrigo A. articleopenAccess
1132011Synaptic localization of the amyloid precursor protein in the rat hippocampusRodrigues, Diana Isabel Queirós Guedes masterThesisopenAccess
11414-Oct-2020The Coffee-Acrylamide Apparent Paradox: An Example of Why the Health Impact of a Specific Compound in a Complex Mixture Should Not Be Evaluated in IsolationNehlig, Astrid; Cunha, Rodrigo A. articleopenAccess
11516-Jul-2018The exercise sex gap and the impact of the estrous cycle on exercise performance in miceAguiar, Aderbal S. ; Speck, Ana Elisa ; Amaral, Inês M. ; Canas, Paula M. ; Cunha, Rodrigo A. articleopenAccess
11625-Aug-2017The Parkinson's disease-associated GPR37 receptor interacts with striatal adenosine A2A receptor controlling its cell surface expression and function in vivoMorató, Xavier; Luján, Rafael; López-Cano, Marc; Gandía, Jorge; Stagljar, Igor; Watanabe, Masahiko; Cunha, Rodrigo A. ; Fernández-Dueñas, Víctor; Ciruela, Francisco articleopenAccess
11716-Nov-2018THE ROLE OF ADENOSINE A2A RECEPTOR IN THE MIGRATION OF CORTICAL PRINCIPAL NEURONSMorais, Patrícia Sofia Alçada Tomás de doctoralThesisembargoedAccess
11829-Jan-2019The role of P2 receptors in the migration of medial ganglionic eminence-derived interneuronsFerreira, Sofia Alexandra Ramos doctoralThesisembargoedAccess
119Dec-2023The striatum drives the ergogenic effects of caffeinede Bem Alves, Ana Cristina; Speck, Ana Elisa ; Farias, Hémelin Resende; Martins, Leo Meira; Dos Santos, Naiara Souza; Pannata, Gabriela; Tavares, Ana Paula Gomes ; de Oliveira, Jade; Tomé, Ângelo R. ; Cunha, Rodrigo A. ; Aguiar, Aderbal S. articleopenAccess
1202002Transducing system operated by adenosine A2A receptors to facilitate acetylcholine release in the rat hippocampusRebola, Nelson ; Oliveira, Catarina R. ; Cunha, Rodrigo A. articleopenAccess
1215-Oct-2017Treatment with A2A receptor antagonist KW6002 and caffeine intake regulate microglia reactivity and protect retina against transient ischemic damageBoia, Raquel ; Elvas, Filipe ; Madeira, Maria H. ; Aires, Inês D. ; Rodrigues-Neves, Ana C. ; Tralhão, Pedro ; Szabó, Eszter C; Baqi, Younis; Müller, Christa E. ; Tomé, Ângelo R. ; Cunha, Rodrigo A. ; Ambrósio, Francisco ; Santiago, Ana R. articleopenAccess
1222006Trkb receptors modulation of glutamate release is limited to a subset of nerve terminals in the adult rat hippocampusPereira, Daniela B. ; Rebola, Nelson ; Rodrigues, Ricardo J. ; Cunha, Rodrigo A. ; Carvalho, Arsélio P. ; Duarte, Carlos B. articleopenAccess
1237-Aug-2019Validation of an LC-MS/MS Method for the Quantification of Caffeine and Theobromine Using Non-Matched Matrix Calibration CurveMendes, Vera M. ; Coelho, Margarida ; Tomé, Ângelo R. ; Cunha, Rodrigo A. ; Manadas, Bruno articleopenAccess

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