Rego, A. Cristina
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Credit Name
Rego, A. Cristina
Name
Rego, A. Cristina
Variants
Rego, Ana Cristina
Rego, A. C.
Rego, A. C.
Unidade de I&D
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Status
UC Researcher
Biography
Ana Cristina Rego (Ph.D.) is Associate Professor at the Faculty of Medicine, University of Coimbra (FMUC), lecturing classes of Biochemistry, Neuroscience and Neurobiology, and is head of the research group ‘Mitochondria and Neurodegenerative Disorders’ (current designation) at the Center for Neuroscience and Cell Biology (CNC), Univ. Coimbra (UC), since 2003. AC Rego initiated as Teaching Assistant in 1997 at FMUC, was Assistant Professor since 1999, and received the Tenure positition in 2004 and the 'Agregação' degree in 2010. AC Rego obtained the Master degree in Cell Biology in 1994 and the Ph.D. in Cell Biology in 1999 at UC, under the supervision of Prof. Catarina R. Oliveira, and was postdoctoral researcher in the Lab of Prof. David G. Nicholls, at the Univ. Dundee, Scotland, UK, and visiting researcher at the Buck Institute, Novato, CA, USA (David Nicholls Lab), from 1998-2000. In 2004-05 AC Rego was the coordinator of the BEB PhD Programme at CNC. The research group coordinated by AC Rego at CNC-UC investigates molecular mechanisms of familial and age-related neurodegenerative disorders, including Huntington’s and Alzheimer’s diseases, focusing on changes in mitochondrial function, dynamics and biogenesis and metabolic deregulation, glutamatergic postsynaptic dysfunction, and related exosomal content. Funding has been garnered by HighQ Foundation (USA), Lundbeck Foundation, ‘Instituto de Investigação Interdisciplinar’ (IIIUC), ‘Fundação para a Ciência e a Tecnologia’ (FCT) and EHDN-European Huntington Disease Network projects, two 1st edition major‘prizes/awards promoted by Santa Casa da Misericórdia de Lisboa’ (SCML) and ‘Fundação Luso Americana para o Desenvolvimento’ (FLAD) , as well as through industry contracts (e.g. TEVA, Sigma-Tau, Mycology Lab). AC Rego holds a H-factor of 44 (i10=98, at Google Scholar) and ~6400 citations, published 117 peer-reviewed articles (92 original publications), 23 book chapters (11 in portuguese) and more than 110 abstracts in research meetings. AC Rego also supervised/co-supervised the work of several post-doctoral fellows and a 'Ciência-FCT' researcher, 18 Ph.D. students and 37 Master students (concluded degrees). AC Rego acts as a reviewer for scientific journals and funding bodies, including Parkinson's UK, Alzheimer’s Research UK, Austrian Science Fund (FWF), Agence Nationale de la Recherche (ANR), Auckland Medical Research Foundation (AMRF), Telethon Fondazione, Israel Science Foundation, Wellcome Trust and Alzheimer’s Association. ACR is member of the ERA-Chair recruitment and monitoring team ERAatUC, at University of Coimbra, member of the board of CNC-UC, Vice-President of the Portuguese Brain Council and President of the Portuguese Society for Neuroscience (SPN).
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Results 1-17 of 17 (Search time: 0.05 seconds).
| Issue Date | Title | Author(s) | Type | Access | |
|---|---|---|---|---|---|
| 1 | Feb-2015 | Activation of IGF-1 and Insulin Signaling Pathways Ameliorate Mitochondrial Function and Energy Metabolism in Huntington’s Disease Human Lymphoblasts | Naia, Luana ; Ferreira, I. Luísa ; Cunha-Oliveira, Teresa ; Duarte, Ana I. ; Ribeiro, Márcio ; Rosenstock, Tatiana R. ; Laço, Mário N. ; Ribeiro, Maria J. ; Oliveira, Catarina R. ; Saudou, Frédéric ; Humbert, Sandrine ; Rego, A. Cristina | article | openAccess |
| 2 | 1-Jan-2023 | Apoe4 and Alzheimer's Disease Pathogenesis-Mitochondrial Deregulation and Targeted Therapeutic Strategies | Pires, Mariana ; Rego, A. Cristina | article | openAccess |
| 3 | 2003 | Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis | Gil, Joana ; Almeida, Sandra ; Oliveira, Catarina R. ; Rego, A. Cristina | article | openAccess |
| 4 | 2004 | FK506 prevents mitochondrial-dependent apoptotic cell death induced by 3-nitropropionic acid in rat primary cortical cultures | Almeida, Sandra ; Domingues, António ; Rodrigues, Luís ; Oliveira, Catarina R. ; Rego, A. Cristina | article | openAccess |
| 5 | 2001 | Glutamate regulates the viability of retinal cells in culture | Rego, A. Cristina ; Santos, Maria Sancha ; Areias, Filipe ; Proença, Teresa ; Oliveira, Catarina R. | article | openAccess |
| 6 | 1999 | Glutamate-mediated inhibition of oxidative phosphorylation in cultured retinal cells | Rego, Ana Cristina ; Sancha Santos, Maria ; Oliveira, Catarina Resende | article | openAccess |
| 7 | 8-Mar-2017 | Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's Disease | Naia, Luana ; Cunha-Oliveira, Teresa ; Rodrigues, Joana ; Rosenstock, Tatiana R. ; Oliveira, Ana ; Ribeiro, Márcio ; Carmo, Catarina ; Oliveira-Sousa, Sofia I. ; Duarte, Ana I. ; Hayden, Michael R. ; Rego, A. Cristina | article | openAccess |
| 8 | Sep-2014 | Insulin and IGF-1 improve mitochondrial function in a PI-3K/Akt-dependent manner and reduce mitochondrial generation of reactive oxygen species in Huntington’s disease knock-in striatal cells | Ribeiro, Márcio ; Rosenstock, Tatiana R. ; Oliveira, Ana M. ; Oliveira, Catarina R. ; Rego, A. Cristina | article | openAccess |
| 9 | 5-Nov-2020 | Microbial BMAA elicits mitochondrial dysfunction, innate immunity activation, and Alzheimer's disease features in cortical neurons | Silva, Diana F. ; Candeias, Emanuel ; Esteves, Ana Raquel Fernandes ; Magalhães, João Duarte ; Ferreira, I. Luísa ; Nunes-Costa, Daniela ; Rego, Ana Cristina ; Empadinhas, Nuno ; Cardoso, Sandra M. | article | openAccess |
| 10 | 16-Nov-2020 | Mitochondrial dynamics and mitophagy in cellular models of Parkinson's Disease | Santos, Bruno Miguel Sequeira dos | masterThesis | openAccess |
| 11 | 3-Oct-2023 | Mitochondrial Dysfunction and Decreased Cytochrome c in Cell and Animal Models of Machado-Joseph Disease | Almeida, Filipa ; Ferreira, Ildete L. ; Naia, Luana ; Marinho, Daniela ; Vilaça-Ferreira, Ana Catarina; Costa, Marta D.; Duarte-Silva, Sara; Maciel, Patrícia ; Rego, A. Cristina | article | openAccess |
| 12 | 22-Jul-2019 | Mitochondrial respiratory chain complexes and antioxidant enzymes analyses in diabetes and chronic periodontitis-derived human blood mononuclear cells | Fokt, Olga | masterThesis | embargoedAccess |
| 13 | 24-Mar-2021 | Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling | Naia, Luana Carvalho ; Pinho, Catarina M.; Dentoni, Giacomo; Liu, Jianping; Leal, Nuno Santos; Ferreira, Duarte M. S.; Schreiner, Bernadette; Filadi, Riccardo; Fão, Lígia ; Connolly, Niamh M. C.; Forsell, Pontus; Nordvall, Gunnar; Shimozawa, Makoto; Greotti, Elisa; Basso, Emy; Theurey, Pierre; Gioran, Anna; Joselin, Alvin; Arsenian-Henriksson, Marie; Nilsson, Per; Rego, A. Cristina ; Ruas, Jorge L.; Park, David; Bano, Daniele; Pizzo, Paola; Prehn, Jochen H. M.; Ankarcrona, Maria | article | openAccess |
| 14 | 9-Nov-2021 | Neuroprotection of retinal ganglion cells by the sigma-1 receptor agonist pridopidine in models of experimental glaucoma | Geva, Michal; Gershoni-Emek, Noga; Naia, Luana ; Ly, Philip; Mota, Sandra ; Rego, Ana Cristina ; Hayden, Michael R. ; Levin, Leonard A. | article | openAccess |
| 15 | Aug-2023 | Reduction of class I histone deacetylases ameliorates ER-mitochondria cross-talk in Alzheimer's disease | Marinho, Daniela ; Ferreira, Ildete L. ; Lorenzoni, Ricardo ; Cardoso, Sandra M. ; Santana, Isabel ; Rego, A. Cristina | article | openAccess |
| 16 | Sep-2013 | Reprint of: Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of abuse | Perfeito, Rita ; Cunha-Oliveira, Teresa ; Rego, Ana Cristina | article | openAccess |
| 17 | 25-Jan-2017 | Role of lysine deacetylases on transcription regulation and mitochondrial function in Huntington's disease | Naia, Luana Carvalho | doctoralThesis | openAccess |