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Credit Name
Rego, A. Cristina
 
Name
Rego, A. Cristina
 
Variants
Rego, Ana Cristina
Rego, A. C.
 
 
 
Ciência ID
 
Status
UC Researcher
Biography
Ana Cristina Rego (Ph.D.) is Associate Professor at the Faculty of Medicine, University of Coimbra (FMUC), lecturing classes of Biochemistry, Neuroscience and Neurobiology, and is head of the research group ‘Mitochondria and Neurodegenerative Disorders’ (current designation) at the Center for Neuroscience and Cell Biology (CNC), Univ. Coimbra (UC), since 2003. AC Rego initiated as Teaching Assistant in 1997 at FMUC, was Assistant Professor since 1999, and received the Tenure positition in 2004 and the 'Agregação' degree in 2010. AC Rego obtained the Master degree in Cell Biology in 1994 and the Ph.D. in Cell Biology in 1999 at UC, under the supervision of Prof. Catarina R. Oliveira, and was postdoctoral researcher in the Lab of Prof. David G. Nicholls, at the Univ. Dundee, Scotland, UK, and visiting researcher at the Buck Institute, Novato, CA, USA (David Nicholls Lab), from 1998-2000. In 2004-05 AC Rego was the coordinator of the BEB PhD Programme at CNC. The research group coordinated by AC Rego at CNC-UC investigates molecular mechanisms of familial and age-related neurodegenerative disorders, including Huntington’s and Alzheimer’s diseases, focusing on changes in mitochondrial function, dynamics and biogenesis and metabolic deregulation, glutamatergic postsynaptic dysfunction, and related exosomal content. Funding has been garnered by HighQ Foundation (USA), Lundbeck Foundation, ‘Instituto de Investigação Interdisciplinar’ (IIIUC), ‘Fundação para a Ciência e a Tecnologia’ (FCT) and EHDN-European Huntington Disease Network projects, two 1st edition major‘prizes/awards promoted by Santa Casa da Misericórdia de Lisboa’ (SCML) and ‘Fundação Luso Americana para o Desenvolvimento’ (FLAD) , as well as through industry contracts (e.g. TEVA, Sigma-Tau, Mycology Lab). AC Rego holds a H-factor of 44 (i10=98, at Google Scholar) and ~6400 citations, published 117 peer-reviewed articles (92 original publications), 23 book chapters (11 in portuguese) and more than 110 abstracts in research meetings. AC Rego also supervised/co-supervised the work of several post-doctoral fellows and a 'Ciência-FCT' researcher, 18 Ph.D. students and 37 Master students (concluded degrees). AC Rego acts as a reviewer for scientific journals and funding bodies, including Parkinson's UK, Alzheimer’s Research UK, Austrian Science Fund (FWF), Agence Nationale de la Recherche (ANR), Auckland Medical Research Foundation (AMRF), Telethon Fondazione, Israel Science Foundation, Wellcome Trust and Alzheimer’s Association. ACR is member of the ERA-Chair recruitment and monitoring team ERAatUC, at University of Coimbra, member of the board of CNC-UC, Vice-President of the Portuguese Brain Council and President of the Portuguese Society for Neuroscience (SPN).
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Publications

Refined By:
Type:  masterThesis

Results 1-22 of 22 (Search time: 3.12 seconds).

Issue DateTitleAuthor(s)TypeAccess
127-Sep-20182B or not 2B that is the question about the synaptic proteasome in glutamatergic synapsesÁguas, Rodolfo das Neves masterThesisopenAccess
2Sep-2016Amyloid-beta peptide-evoked Src signaling and redox changes in hippocampal cellsFão, Lígia Vanessa Rocha masterThesisopenAccess
314-Jun-2017Autophagy in Neurodegeneration: Latest developments on eating ourselves out of diseaseFigueiredo, Pedro Xavier Pinto de masterThesisopenAccess
42013Aβ-mediated changes in CREB and ERK activity in cultured cortical neurons: involvement of NMDA receptorsRosa, Valeria de masterThesisopenAccess
52009Cell therapy in brain neurodegenerative movement disorders :a clinical perspectiveRibeiro, Ana Cláudia Saraiva masterThesisopenAccess
62012Changes in transcription factors related to mitochondrial biogenesis and antioxidant defense in alzheimer’s disease modelsCaldeira, Gladys Tarcila Lima masterThesisopenAccess
72016Characterization of mitochondrial function and dynamics in models of Machado-Joseph diseaseAlmeida, Filipa Luísa Lourenço de masterThesisembargoedAccess
819-Jul-2018Characterization of the postsynaptic density in a transgenic mouse model of Huntington’s diseasePassos, Diogo André Malheiro masterThesisembargoedAccess
92016Early mitochondrial modifications in YAC128 transgenic model of Huntington’s diseaseMaranga, Carina Sofia Barradas masterThesisembargoedAccess
102011Excitotoxicidade em células granulares do cerebelo que expressam ataxina-3 mutante - relevância para a patogénese da doença de Machado-JosephSousa, Sofia Isabel Oliveira masterThesisopenAccess
112015Increasesd brain levels of hydrogen peroxide in a transgenic mouse model of Huntington's diseaseLaço, Mário Luís Nôro masterThesisembargoedAccess
122012Investigação do mtDNA nas doenças de Huntington e ParkinsonFernandes, Sabrina masterThesisopenAccess
1324-Feb-2021Linking mitochondrial Src and hippocampal dendritic changes in Alzheimer's diseaseNeves, Laura Alexandrina SequeiramasterThesisopenAccess
146-Sep-2019Mitochondrial characterization in Huntington's Disease fibroblasts and iPSC-derived cellsBeatriz, Margarida FernandesmasterThesisembargoedAccess
1516-Nov-2020Mitochondrial dynamics and mitophagy in cellular models of Parkinson's DiseaseSantos, Bruno Miguel Sequeira dosmasterThesisopenAccess
167-Jul-2017Mitochondrial function analysis in diabetes and chronic periodontitis-derived human blood cells: role of resistinCosta, Ana Solange Gomes masterThesisembargoedAccess
1722-Jul-2019Mitochondrial respiratory chain complexes and antioxidant enzymes analyses in diabetes and chronic periodontitis-derived human blood mononuclear cellsFokt, Olga masterThesisembargoedAccess
18Jul-2010Peripheral and cerebral metabolic features in an animal model of huntington's disease expressing full-length mutant huntingtinLopes, Carla Maria Nunes masterThesisopenAccess
192012Pyruvate dehydrogenase and mitochondrial function in Huntington’s disease – influence of insulin/IGF and histone deacetylase inhibitorsRodrigues, Joana Cristina P. masterThesisopenAccess
20Mar-2013Role of alpha-synuclein in neurodegenerationNoronha, Carolina de Freitas masterThesisopenAccess
212013Role of selective kinases and GDNF on iron-mediated alpha-synuclein phosphorylation-relevance to Parkinson's diseaseSantos, Paulo André Ribeiro dos masterThesisopenAccess
222015The role of GHSR1 in dentate gyrus adult neurogenesisDias, Inês Saragoça masterThesisopenAccess