Rego, A. Cristina
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Rego, A. Cristina
Name
Rego, A. Cristina
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Rego, Ana Cristina
Rego, A. C.
Rego, A. C.
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UC Researcher
Biography
Ana Cristina Rego (Ph.D.) is Associate Professor at the Faculty of Medicine, University of Coimbra (FMUC), lecturing classes of Biochemistry, Neuroscience and Neurobiology, and is head of the research group ‘Mitochondria and Neurodegenerative Disorders’ (current designation) at the Center for Neuroscience and Cell Biology (CNC), Univ. Coimbra (UC), since 2003. AC Rego initiated as Teaching Assistant in 1997 at FMUC, was Assistant Professor since 1999, and received the Tenure positition in 2004 and the 'Agregação' degree in 2010. AC Rego obtained the Master degree in Cell Biology in 1994 and the Ph.D. in Cell Biology in 1999 at UC, under the supervision of Prof. Catarina R. Oliveira, and was postdoctoral researcher in the Lab of Prof. David G. Nicholls, at the Univ. Dundee, Scotland, UK, and visiting researcher at the Buck Institute, Novato, CA, USA (David Nicholls Lab), from 1998-2000. In 2004-05 AC Rego was the coordinator of the BEB PhD Programme at CNC. The research group coordinated by AC Rego at CNC-UC investigates molecular mechanisms of familial and age-related neurodegenerative disorders, including Huntington’s and Alzheimer’s diseases, focusing on changes in mitochondrial function, dynamics and biogenesis and metabolic deregulation, glutamatergic postsynaptic dysfunction, and related exosomal content. Funding has been garnered by HighQ Foundation (USA), Lundbeck Foundation, ‘Instituto de Investigação Interdisciplinar’ (IIIUC), ‘Fundação para a Ciência e a Tecnologia’ (FCT) and EHDN-European Huntington Disease Network projects, two 1st edition major‘prizes/awards promoted by Santa Casa da Misericórdia de Lisboa’ (SCML) and ‘Fundação Luso Americana para o Desenvolvimento’ (FLAD) , as well as through industry contracts (e.g. TEVA, Sigma-Tau, Mycology Lab). AC Rego holds a H-factor of 44 (i10=98, at Google Scholar) and ~6400 citations, published 117 peer-reviewed articles (92 original publications), 23 book chapters (11 in portuguese) and more than 110 abstracts in research meetings. AC Rego also supervised/co-supervised the work of several post-doctoral fellows and a 'Ciência-FCT' researcher, 18 Ph.D. students and 37 Master students (concluded degrees). AC Rego acts as a reviewer for scientific journals and funding bodies, including Parkinson's UK, Alzheimer’s Research UK, Austrian Science Fund (FWF), Agence Nationale de la Recherche (ANR), Auckland Medical Research Foundation (AMRF), Telethon Fondazione, Israel Science Foundation, Wellcome Trust and Alzheimer’s Association. ACR is member of the ERA-Chair recruitment and monitoring team ERAatUC, at University of Coimbra, member of the board of CNC-UC, Vice-President of the Portuguese Brain Council and President of the Portuguese Society for Neuroscience (SPN).
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Results 1-55 of 55 (Search time: 0.001 seconds).
| Issue Date | Title | Author(s) | Type | Access | |
|---|---|---|---|---|---|
| 1 | 27-Sep-2018 | 2B or not 2B that is the question about the synaptic proteasome in glutamatergic synapses | Águas, Rodolfo das Neves | masterThesis | openAccess |
| 2 | Feb-2015 | Activation of IGF-1 and Insulin Signaling Pathways Ameliorate Mitochondrial Function and Energy Metabolism in Huntington’s Disease Human Lymphoblasts | Naia, Luana ; Ferreira, I. Luísa ; Cunha-Oliveira, Teresa ; Duarte, Ana I. ; Ribeiro, Márcio ; Rosenstock, Tatiana R. ; Laço, Mário N. ; Ribeiro, Maria J. ; Oliveira, Catarina R. ; Saudou, Frédéric ; Humbert, Sandrine ; Rego, A. Cristina | article | openAccess |
| 3 | Sep-2016 | Amyloid-beta peptide-evoked Src signaling and redox changes in hippocampal cells | Fão, Lígia Vanessa Rocha | masterThesis | openAccess |
| 4 | 14-Jun-2017 | Autophagy in Neurodegeneration: Latest developments on eating ourselves out of disease | Figueiredo, Pedro Xavier Pinto de | masterThesis | openAccess |
| 5 | Feb-2015 | Aβ and NMDAR activation cause mitochondrial dysfunction involving ER calcium release | Ferreira, Ildete Luísa ; Ferreiro, Elisabete ; Schmidt, Jeannette ; Cardoso, João M. ; Pereira, Cláudia M. F. ; Carvalho, Ana Luísa ; Oliveira, Catarina R. ; Rego, A. Cristina | article | openAccess |
| 6 | 2013 | Aβ-mediated changes in CREB and ERK activity in cultured cortical neurons: involvement of NMDA receptors | Rosa, Valeria de | masterThesis | openAccess |
| 7 | Sep-2011 | Bioenergetic dysfunction in Huntington's disease human cybrids | Ferreira, I. Luísa ; Cunha-Oliveira, Teresa ; Nascimento, Maria V. ; Ribeiro, Márcio ; Proença, M. Teresa ; Januário, Cristina ; Oliveira, Catarina R. ; Rego, A. Cristina | article | openAccess |
| 8 | 2012 | Changes in transcription factors related to mitochondrial biogenesis and antioxidant defense in alzheimer’s disease models | Caldeira, Gladys Tarcila Lima | masterThesis | openAccess |
| 9 | 10-Feb-2015 | Characterization of human stem cells and therapeutic strategies involving IGF-1 and shRNA in Huntington's disease | Lopes, Carla Maria Nunes | doctoralThesis | embargoedAccess |
| 10 | 2016 | Characterization of mitochondrial function and dynamics in models of Machado-Joseph disease | Almeida, Filipa Luísa Lourenço de | masterThesis | embargoedAccess |
| 11 | 19-Jul-2018 | Characterization of the postsynaptic density in a transgenic mouse model of Huntington’s disease | Passos, Diogo André Malheiro | masterThesis | embargoedAccess |
| 12 | 26-Apr-2019 | Chronic stress triggers divergent dendritic alterations in immature neurons of the adult hippocampus, depending on their ultimate terminal fields | Dioli, Chrysoula; Patrício, Patrícia; Sousa, Nuno; Kokras, Nikolaos; Dalla, Christina; Guerreiro, Sara ; Santos-Silva, Miguel A.; Rego, Ana Cristina ; Pinto, Luísa ; Ferreiro, Elisabete ; Sotiropoulos, Ioannis | article | openAccess |
| 13 | Feb-2012 | Consequences of mitochondrial dysfunction in Huntington's Disease and protection via phosphorylation pathways | Cunha-Oliveira, Teresa ; Ferreira, Ildete L. ; Rego, A. Cristina | bookPart | openAccess |
| 14 | 31-Aug-2018 | Coriolus versicolor biomass increases dendritic arborization of newly-generated neurons in mouse hippocampal dentate gyrus | Ferreiro, Elisabete ; Pita, Inês R. ; Mota, Sandra ; Valero, Jorge ; Ferreira, Nuno R. ; Fernandes, Tito; Calabrese, Vittorio; Fontes-Ribeiro, Carlos A. ; Pereira, Frederico C. ; Rego, Ana Cristina | article | openAccess |
| 15 | Sep-2012 | Disruption of striatal glutamatergic/GABAergic homeostasis following acute methamphetamine in mice | Pereira, Frederico ; Cunha-Oliveira, Teresa ; Viana, Sofia ; Travassos, Ana Sofia ; Nunes, Sara ; Silva, Carlos ; Prediger, Rui ; Rego, Ana Cristina ; Ali, Syed ; Fontes Ribeiro, Carlos Alberto | article | closedAccess |
| 16 | 2016 | Dominant-Negative Effects of Adult-Onset Huntingtin Mutations Alter the Division of Human Embryonic Stem Cells-Derived Neural Cells | Lopes, Carla ; Aubert, Sophie ; Bourgois-Rocha, Fany ; Barnat, Monia ; Rego, Ana Cristina ; Déglon, Nicole ; Perrier, Anselme L. ; Humbert, Sandrine | article | openAccess |
| 17 | 8-Mar-2012 | Drugs of abuse induce apoptotic features in PC12 cells. | Oliveira, M. Teresa ; Rego, A. Cristina ; Macedo, Tice R. ; Oliveira, Catarina R. | article | openAccess |
| 18 | Jan-2014 | Dysfunctional synapse in Alzheimer’s disease – a focus on NMDA receptors | Mota, Sandra I. ; Ferreira, Ildete L. ; Rego, A. Cristina | article | openAccess |
| 19 | 2016 | Early mitochondrial modifications in YAC128 transgenic model of Huntington’s disease | Maranga, Carina Sofia Barradas | masterThesis | embargoedAccess |
| 20 | 9-Mar-2012 | Efeito crónico da heroína e do peróxido de hidrogénio em células PC12 | Cunha-Oliveira, Teresa ; Rego, A. Cristina ; Morgadinho, M. Teresa ; Macedo, Tice R. ; Oliveira, Catarina R. | article | openAccess |
| 21 | 2011 | Excitotoxicidade em células granulares do cerebelo que expressam ataxina-3 mutante - relevância para a patogénese da doença de Machado-Joseph | Sousa, Sofia Isabel Oliveira | masterThesis | openAccess |
| 22 | 8-Mar-2012 | Expression of NR1/NR2B N-Methyl-d-Aspartate Receptors Enhances Heroin Toxicity in HEK293 Cells | Domingues, António ; Cunha-Oliveira, Teresa ; Laço, Mário L. N. ; Macedo, Tice ; Oliveira, Catarina R. ; Rego, A. Cristina | article | openAccess |
| 23 | 15-Nov-2012 | Glutathione redox cycle dysregulation in Huntington’s disease knock-in striatal cells | Ribeiro, Márcio ; Rosenstock, Tatiana ; Cunha-Oliveira, Teresa ; Ferreira, Ildete ; Oliveira, Catarina R. ; Rego, Ana Cristina | article | openAccess |
| 24 | 8-Mar-2017 | Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's Disease | Naia, Luana ; Cunha-Oliveira, Teresa ; Rodrigues, Joana ; Rosenstock, Tatiana R. ; Oliveira, Ana ; Ribeiro, Márcio ; Carmo, Catarina ; Oliveira-Sousa, Sofia I. ; Duarte, Ana I. ; Hayden, Michael R. ; Rego, A. Cristina | article | openAccess |
| 25 | 2015 | Increasesd brain levels of hydrogen peroxide in a transgenic mouse model of Huntington's disease | Laço, Mário Luís Nôro | masterThesis | embargoedAccess |
| 26 | Sep-2014 | Insulin and IGF-1 improve mitochondrial function in a PI-3K/Akt-dependent manner and reduce mitochondrial generation of reactive oxygen species in Huntington’s disease knock-in striatal cells | Ribeiro, Márcio ; Rosenstock, Tatiana R. ; Oliveira, Ana M. ; Oliveira, Catarina R. ; Rego, A. Cristina | article | openAccess |
| 27 | 2012 | Interplay between Alpha-Synuclein and Oxidative Stress in Parkinson´s Disease Cell Models | Perfeito, Rita Catarina Gonçalves | doctoralThesis | openAccess |
| 28 | 2012 | Investigação do mtDNA nas doenças de Huntington e Parkinson | Fernandes, Sabrina | masterThesis | openAccess |
| 29 | 2015 | Limited Effect of Chronic Valproic Acid Treatment in a Mouse Model of Machado-Joseph Disease | Esteves, Sofia; Duarte-Silva, Sara; Naia, Luana ; Neves-Carvalho, Andreia; Teixeira-Castro, Andreia ; Rego, Ana Cristina ; Silva-Fernandes, Anabela; Maciel, Patrícia | article | openAccess |
| 30 | 2013 | Medical Toxicology of Drugs of Abuse | Cunha-Oliveira, Teresa ; Rego, Ana Cristina ; Carvalho, Félix ; Oliveira, Catarina R. | bookPart | openAccess |
| 31 | 6-Sep-2019 | Mitochondrial characterization in Huntington's Disease fibroblasts and iPSC-derived cells | Beatriz, Margarida Fernandes | masterThesis | embargoedAccess |
| 32 | 7-Jul-2017 | Mitochondrial function analysis in diabetes and chronic periodontitis-derived human blood cells: role of resistin | Costa, Ana Solange Gomes | masterThesis | embargoedAccess |
| 33 | 22-Jul-2019 | Mitochondrial respiratory chain complexes and antioxidant enzymes analyses in diabetes and chronic periodontitis-derived human blood mononuclear cells | Fokt, Olga | masterThesis | embargoedAccess |
| 34 | 2012 | Mitochondrial- and endoplasmic reticulum-associated oxidative stress in Alzheimer's disease: from pathogenesis to biomarkers | Ferreiro, E. ; Baldeiras, I. ; Ferreira, I. L. ; Costa, R. O. ; Rego, A. C. ; Pereira, C. F. ; Oliveira, C. R. | article | openAccess |
| 35 | 27-Feb-2013 | Molecular Cascades in Midbrain Dopaminenergic Neuron Development: Emphasis on Wnts | Oliveira, Ana Catarina Henriques | doctoralThesis | openAccess |
| 36 | 2011 | Molecular interaction between cocaine and opioids. Implications on Speedball's toxicity | Cunha-Oliveira, T. ; Silva, L. ; Silva, A. M. ; Santos, M. S. ; Garrido, J. ; Borges, F. ; Rego, A. C. ; Oliveira, C. R. | conferenceObject | openAccess |
| 37 | 5-Apr-2017 | Neurobiology of the circadian clock: Metabolism control & Implications for Alzheimer´s disease | Silva, Antonio Manuel Carvalho da | doctoralThesis | openAccess |
| 38 | 2012 | Neurotoxicity of cocaine | Cunha-Oliveira, Teresa ; Rego, A. Cristina ; Oliveira, Catarina R. | bookPart | openAccess |
| 39 | 8-Mar-2012 | Neurotoxicity of heroin-cocaine combinations in rat cortical neurons | Cunha-Oliveira, Teresa ; Rego, A. Cristina ; Garrido, Jorge ; Borges, Fernanda ; Macedo, Tice ; Oliveira, Catarina R. | article | openAccess |
| 40 | 9-May-2013 | NMDA receptors-associated events and oxidative stress in models of Alzheimer's Disease | Mota, Sandra Isabel Freitas | doctoralThesis | openAccess |
| 41 | 28-Aug-2014 | Oxidative Stress and Drugs of Abuse: An Update | Cunha-Oliveira, Teresa ; Rego, A. Cristina ; Oliveira, Catarina R. | article | openAccess |
| 42 | 9-Jul-2014 | Oxidative stress in Huntington's disease knock-in striatal cells | Ribeiro, Márcio José do Coito | doctoralThesis | openAccess |
| 43 | Jul-2010 | Peripheral and cerebral metabolic features in an animal model of huntington's disease expressing full-length mutant huntingtin | Lopes, Carla Maria Nunes | masterThesis | openAccess |
| 44 | 2012 | Pyruvate dehydrogenase and mitochondrial function in Huntington’s disease – influence of insulin/IGF and histone deacetylase inhibitors | Rodrigues, Joana Cristina P. | masterThesis | openAccess |
| 45 | Sep-2013 | Reprint of: Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of abuse | Perfeito, Rita ; Cunha-Oliveira, Teresa ; Rego, Ana Cristina | article | openAccess |
| 46 | 1-Nov-2012 | Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease-resemblance to the effect of amphetamine drugs of abuse | Perfeito, Rita ; Cunha-Oliveira, Teresa ; Rego, Ana Cristina | article | openAccess |
| 47 | Mar-2013 | Role of alpha-synuclein in neurodegeneration | Noronha, Carolina de Freitas | masterThesis | openAccess |
| 48 | 11-Apr-2013 | Role of Brain-Derived Neurotrophic Factor and Mitochondrial Function in Huntington's Disease | Silva, Ana Cristina Rosa da | doctoralThesis | openAccess |
| 49 | 25-Jan-2017 | Role of lysine deacetylases on transcription regulation and mitochondrial function in Huntington's disease | Naia, Luana Carvalho | doctoralThesis | openAccess |
| 50 | 2013 | Role of selective kinases and GDNF on iron-mediated alpha-synuclein phosphorylation-relevance to Parkinson's disease | Santos, Paulo André Ribeiro dos | masterThesis | openAccess |
| 51 | Sep-2019 | Shaping the Nrf2-ARE-related pathways in Alzheimer's and Parkinson's diseases | Fão, Lígia ; Mota, Sandra ; Rego, Ana Cristina | article | openAccess |
| 52 | 17-Dec-2012 | Studies on the activity of ataxin-3 and miyochondrial dysfunction in models of Machado-Joseph disease | Laço, Mário Luís Nôro | doctoralThesis | openAccess |
| 53 | 2015 | The role of GHSR1 in dentate gyrus adult neurogenesis | Dias, Inês Saragoça | masterThesis | openAccess |
| 54 | 8-Mar-2012 | Toxic Effects of Opioid and Stimulant Drugs on Undifferentiated PC12 Cells | Oliveira, M. Teresa ; Rego, A. Cristina ; Morgadinho, M. Teresa ; Macedo, Tice R. ; Oliveira, Catarina R. | article | openAccess |
| 55 | 2012 | Valosin-containing protein (VCP/p97) is an activator of wild-type ataxin-3 | Laço, Mário N. ; Cortes, Luísa ; Travis, Sue M.; Paulson, Henry L.; Rego, A. Cristina | article | openAccess |