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Credit Name
Santana, Isabel
 
Name
Santana, Isabel J.
 
Variants
Santana, Isabel
Santana, I.
 
 
 
Ciência ID
 
Scopus Author ID
 
Status
UC Researcher
Biography
Maria Isabel Jacinto Santana graduated in Medicine at the University of Coimbra in 1984, completed is PhD in Neurology (Alzheimer's Disease) in 1999 and is Full Professor of Neurology at the Faculty of Medicine of the University of Coimbra and co-coordinator of the Neurosciences and Mental Health Group since 2019. She is the director of the Neurology Department at the Centro Hospitalar e Universitário de Coimbra, being head of the Memory/Dementia Clinic and the Neuropsychological Unit and coordinator of the Coimbra Center at the European Alzheimers disease Consortium (EADC). Her main areas of expertise are neurodegenerative diseases in both clinical practise and translational investigation, including 20 years of experience in clinical trials and is a member of the National Ethics Committee for Clinical Investigation (CEIC) since 2017. As an integrated Member of the Center for Neuroscience and Cell Biology (CNC-UC) and head of the clinical/translational research group "Biomarkers in Neuropsychiatric Disorders: from Molecules to Diagnosis and Intervention" of the Center for Innovative Biomedicine and Biotechnology. She participates and/or has participated as Principal investigator in 13 project(s) and as Researcher in 26 project(s) with competitive financial support, received 26 awards and/or honors, is author/co-author of over 250 papers (6492 citations/h factor: 41), 31 books/section(s) of books and of more than 500 oral presentations in national and/or international scientific meetings. She has supervised/co-supervised 10 PhD thesis and 51 MSc dissertations.
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Publications

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Results 1-107 of 107 (Search time: 0.001 seconds).

Issue DateTitleAuthor(s)TypeAccess
120-Mar-2018Addition of the Aβ42/40 ratio to the cerebrospinal fluid biomarker profile increases the predictive value for underlying Alzheimer's disease dementia in mild cognitive impairmentBaldeiras, Inês ; Santana, Isabel ; Leitão, Maria João ; Gens, Helena; Pascoal, Rui; Tábuas-Pereira, Miguel ; Beato-Coelho, José; Duro, Diana ; Almeida, Maria do Rosário ; Oliveira, Catarina Resende de articleopenAccess
210-Dec-2020Alterações Emocionais na Doença de Pequenos Vasos Cerebrais Esporádica e CADASIL: Revisão da literatura e estudo exploratórioSantos, Irina Sofia Reis GomesmasterThesisopenAccess
330-May-2018Aphasia Rapid Test: Estudos de Tradução, Adaptação e Validação para a População PortuguesaTábuas-Pereira, Miguel ; Freitas, Sandra ; Beato-Coelho, José; Ribeiro, Joana; Parra, Joana; Martins, Cristina ; Silva, Miguel; Matos, Maria Assunção; Nogueira, Ana Rita; Silva, Fernando; Sargento-Freitas, João ; Cordeiro, Gustavo ; Cunha, Luís ; Santana, Isabel articleopenAccess
4Sep-2012APOE e transformação hemorrágica após administração de alteplase em doentes com acidente vascular cerebral isquémico agudoPedrosa, Isabel Sofia de Sousa masterThesisopenAccess
52006Association of HFE common mutations with Parkinson's disease, Alzheimer's disease and mild cognitive impairment in a Portuguese cohortGuerreiro, Rita J. ; Brás, José M. ; Santana, Isabel ; Januário, Cristina ; Santiago, Beatriz ; Morgadinho, Ana S. ; Ribeiro, Maria H. ; Hardy, John ; Singleton, Andrew ; Oliveira, Catarina articleopenAccess
6Feb-2023Associations between cortical β-amyloid burden, fornix microstructure and cognitive processing of faces, places, bodies and other visual objects in early Alzheimer's diseaseBourbon-Teles, José ; Jorge, Lília ; Canário, Nádia ; Martins, Ricardo ; Santana, Isabel ; Castelo-Branco, Miguel articleopenAccess
73-Apr-2017Behavioral Symptoms in the Variants of Primary Progressive AphasiaMartins, Marta Oliveira masterThesisembargoedAccess
817-Jul-2014Características clínicas de doentes e portadores da expansão hexanucleotídica no gene C9ORF72Pires, José Guilherme Neri Miranda masterThesisopenAccess
9May-2023Cerebellar and subcortical atrophy contribute to psychiatric symptoms in frontotemporal dementiaBussy, Aurélie; Levy, Jake P.; Best, Tristin; Patel, Raihaan; Cupo, Lani; Van Langenhove, Tim; Nielsen, Jørgen E.; Pijnenburg, Yolande; Waldö, Maria Landqvist; Remes, Anne M.; Schroeter, Matthias L.; Santana, Isabel ; Pasquier, Florence; Otto, Markus; Danek, Adrian; Levin, Johannes; Le Ber, Isabelle; Vandenberghe, Rik; Synofzik, Matthis; Moreno, Fermin; de Mendonça, Alexandre; Sánchez-Valle, Raquel ; Laforce, Robert; Langheinrich, Tobias; Gerhard, Alexander; Graff, Caroline; Butler, Chris R.; Sorbi, Sandro; Jiskoot, Lize; Seelaar, Harro; van Swieten, John C.; Finger, Elizabeth; Tartaglia, Maria Carmela; Masellis, Mario; Tiraboschi, Pietro; Galimberti, Daniela; Borroni, Barbara; Rowe, James B.; Bocchetta, Martina; Rohrer, Jonathan D. ; Devenyi, Gabriel A.; Chakravarty, M. Mallar; Ducharme, SimonarticleopenAccess
1030-Jan-2020Cerebrospinal fluid lipocalin 2 as a novel biomarker for the differential diagnosis of vascular dementiaLlorens, Franc; Hermann, Peter; Villar-Piqué, Anna; Diaz-Lucena, Daniela; Nägga, Katarina; Hansson, Oskar; Santana, Isabel ; Schmitz, Matthias; Schmidt, Christian; Varges, Daniela; Goebel, Stefan; Dumurgier, Julien; Zetterberg, Henrik; Blennow, Kaj; Paquet, Claire; Baldeiras, Inês ; Ferrer, Isidro; Zerr, IngaarticleopenAccess
112016Clinical validation of Alzheimer's disease assessment scale - cognitive sub-scale (ADAS-cog) - for the portuguese populationNogueira, Joana masterThesisopenAccess
1223-Nov-2019Clinical validation of the Lumipulse G cerebrospinal fluid assays for routine diagnosis of Alzheimer's diseaseLeitão, Maria João ; Spínola, Anuschka da Silva ; Santana, Isabel ; Olmedo, Veronica; Nadal, Alicia; Le Bastard, Nathalie; Baldeiras, Inês articleopenAccess
132022Cognitive composites for genetic frontotemporal dementia: GENFI-CogPoos, Jackie M; Moore, Katrina M; Nicholas, Jennifer; Russell, Lucy L; Peakman, Georgia; Convery, Rhian S; Jiskoot, Lize C; van der Ende, Emma; van den Berg, Esther; Papma, Janne M; Seelaar, Harro; Pijnenburg, Yolande A L; Moreno, Fermin; Sánchez-Valle, Raquel ; Borroni, Barbara; Laforce, Robert; Masellis, Mario; Tartaglia, Carmela; Graff, Caroline; Galimberti, Daniela; Rowe, James B; Finger, Elizabeth; Synofzik, Matthis; Vandenberghe, Rik; de Mendonça, Alexandre; Tiraboschi, Pietro; Santana, Isabel ; Ducharme, Simon; Butler, Chris; Gerhard, Alexander; Levin, Johannes; Danek, Adrian; Otto, Markus; Le Ber, Isabel; Pasquier, Florence; van Swieten, John C; Rohrer, Jonathan D. articleopenAccess
142021Cognitive Trajectories Following Acute Infection in Older Patients With and Without Cognitive Impairment: An 1-Year Follow-Up StudySilva, Ana Rita ; Regueira, Patrícia; Cardoso, Ana Luísa ; Baldeiras, Inês ; Santana, Isabel ; Cerejeira, Joaquim articleopenAccess
152021Combined Structural MR and Diffusion Tensor Imaging Classify the Presence of Alzheimer's Disease With the Same Performance as MR Combined With Amyloid Positron Emission Tomography: A Data Integration ApproachAgostinho, Daniel ; Caramelo, Francisco ; Moreira, Ana Paula ; Santana, Isabel ; Abrunhosa, Antero ; Castelo Branco, Miguel articleopenAccess
16Nov-2018Congenital heart disease: New challengesSantana, Isabel articleopenAccess
1728-Oct-2019Contributos para o estudo do Funcionamento Cognitivo e Emocional na Doença de Pequenos Vasos CerebraisAntónio, Inês Guedes Santos PatríciomasterThesisopenAccess
18Mar-2013Correlação entre localização e atividade epileptogénica : comparação entre epilepsias focais por tumores benignos e displasias corticais focaisBrás, Ana Catarina Branquinho masterThesisopenAccess
192018Data driven diagnostic classification in Alzheimer's disease based on different reference regions for normalization of PiB-PET images and correlation with CSF concentrations of Aβ speciesOliveira, Francisco ; Leuzy, Antoine; Castelhano, J. ; Chiotis, Konstantinos; Hasselbalch, Steen Gregers; Rinne, Juha; Mendonça, Alexandre de ; Otto, Markus; Lleó, Alberto ; Santana, Isabel ; Johansson, Jarkko; Anderl-Straub, Sarah; Arnim, Christine; Beer, Ambros; Blesa, Rafael ; Fortea, Juan; Sanna-Kaisa, Herukka; Portelius, Erik; Pannee, Josef; Zetterberg, Henrik; Blennow, Kaj; Moreira, Ana P. ; Abrunhosa, Antero ; Nordberg, Agneta; Castelo-Branco, Miguel articleopenAccess
202022Data-driven staging of genetic frontotemporal dementia using multi-modal MRIMcCarthy, Jillian; Borroni, Barbara; Sánchez-Valle, Raquel ; Moreno, Fermin; Laforce, Robert; Graff, Caroline; Synofzik, Matthis; Galimberti, Daniela; Rowe, James B; Masellis, Mario; Tartaglia, Maria Carmela; Finger, Elizabeth; Vandenberghe, Rik; de Mendonça, Alexandre; Tagliavini, Fabrizio ; Santana, Isabel ; Butler, Chris; Gerhard, Alex; Danek, Adrian; Levin, Johannes; Otto, Markus; Frisoni, Giovanni; Ghidoni, Roberta; Sorbi, Sandro; Jiskoot, Lize C; Seelaar, Harro; van Swieten, John C; Rohrer, Jonathan D. ; Iturria-Medina, Yasser; Ducharme, SimonarticleopenAccess
212011Defeito cognitivo ligeiro e doença de Alzheimer : conversão ou progressão?Carmo, João Filipe Guia Alves do masterThesisopenAccess
222010Defeito cognitivo ligeiro e psicopatologiaGonçalves, José Alves Grilo masterThesisopenAccess
232015Defeito cognitivo ligeiro:análise comparativa dos resultados nos testes de recordação selectiva livre e guiada (TRSLG), memória lógica (ML, WMS-III) e memória visuo-espacial (TBMV-VR)Bernardino, Sandra Isabel Teixeira masterThesisopenAccess
2430-Oct-2013Desempenho cognitivo não credível no declínio cognitivo ligeiro: estudos com o Test of Memory Malingering (TOMM) e o Rey-15Item Memory Test (Rey15-IMT)Jesus, Sara Adriana Silva de masterThesisopenAccess
25Feb-2012Determinação do estado redox do líquido céfalo-raquídeo na doença de AlzheimerSardo, Ana Isabel Franganito masterThesisopenAccess
262011Dieta mediterrânica e doença de AlzheimerPereira, Carolina Duarte masterThesisopenAccess
272021Disease-related cortical thinning in presymptomatic granulin mutation carriersBorrego-Écija, Sergi; Sala-Llonch, Roser; van Swieten, John; Borroni, Barbara; Moreno, Fermín; Masellis, Mario; Tartaglia, Carmela; Graff, Caroline; Galimberti, Daniela; Laforce, Robert; Rowe, James B; Finger, Elizabeth; Vandenberghe, Rik; Tagliavini, Fabrizio ; de Mendonça, Alexandre; Santana, Isabel ; Synofzik, Matthis; Ducharme, Simon; Levin, Johannes; Danek, Adrian; Gerhard, Alex; Otto, Markus; Butler, Chris; Frisoni, Giovanni; Sorbi, Sandro; Heller, Carolin; Bocchetta, Martina; Cash, David M; Convery, Rhian S; Moore, Katrina M; Rohrer, Jonathan D. ; Sánchez-Valle, Raquel ; Castelo-Branco, Miguel ; Almeida, Maria do Rosário ; Afonso, Sónia ; Leitão, Maria João ; GENFI Genetic FTD InitiativearticleopenAccess
28Mar-2012Displasia cortical focal e epilepsia : comparação de EEG interictal e ictal com a localização da lesãoPatrocínio, João Pedro Silva Lima masterThesisopenAccess
292016Domain-specific functional organization: neurocognitive characterization of a case of hemi-prosopometamorphopsiaFreixo, Andreia masterThesisopenAccess
3023-Oct-2017A Double Dissociation between Acting on and Knowing How to Act on ToolsValério, Daniela Filipa Codinha masterThesisclosedAccess
31Aug-2022Dual PET-fMRI reveals a link between neuroinflammation, amyloid binding and compensatory task-related brain activity in Alzheimer’s diseaseCanário, Nádia ; Jorge, Lília ; Martins, Ricardo ; Santana, Isabel ; Castelo Branco, Miguel articleopenAccess
3228-Nov-2018Early Transcranial Color-Coded Sonography as a predictor of Hemorrhagic Transformation after ThrombectomyCosta, André Jorge AssunçãomasterThesisembargoedAccess
332011Envelhecimento e défice cognitivo : estudos de adaptação, validação e normalização do Montreal Cognitive Assessment (MoCA)Freitas, Sandra doctoralThesisopenAccess
342015Epidemiologia da Demência e da Doença de Alzheimer em Portugal: Estimativas da Prevalência e dos Encargos Financeiros com a MedicaçãoSantana, Isabel ; Farinha, Filipa ; Freitas, Sandra ; Rodrigues, Vítor ; Carvalho, ÁlvaroarticleopenAccess
35Mar-2010Epidemiologia da demência em PortugalFarinha, Filipa Margarida Cardoso masterThesisopenAccess
365-Jan-2019Erlangen Score as a tool to predict progression from mild cognitive impairment to dementia in Alzheimer's diseaseBaldeiras, Inês ; Santana, Isabel ; Leitão, Maria João ; Vieira, Daniela ; Duro, Diana; Mroczko, Barbara; Kornhuber, Johannes; Lewczuk, PiotrarticleopenAccess
372017Escala de Avaliação da Doença de Alzheimer – Subescala cognitiva (ADAS-Cog): Dados normativo para a população portuguesaNogueira, Joana ; Freitas, Sandra ; Duro, Diana ; Tábuas-Pereira, Miguel ; Guerreiro, Manuela ; Almeida, Jorge ; Santana, Isabel articleopenAccess
38Mar-2012Estudo da personalidade e de sintomas psicopatológicos na epilepsia de lobo temporal por esclerose mesialAndrade, Mariana Lacerda Moreira de Noronha e masterThesisopenAccess
392012Estudo de validação da versão portuguesa da Escala de Avaliação da Incapacidade Funcional na Demência (Disability Assessment for Dementia - DAD)Galhardo, Joana Rita Leonardo masterThesisopenAccess
402010Estudo de validação do Teste de Recordação Selectiva de Buschke – Buschke Selective Reminding TestAfonso, Ana Cristina de Sousa Faria workingPaperopenAccess
41Jan-2016Estudos de adaptação e aplicação de uma Escala de Gravidade da Afasia de causa vascularSilva, Miguel Neves Correia da masterThesisopenAccess
4231-Oct-2014Estudos de validação do Montreal Cognitive Assessment (MoCA) na esclerose múltipla: análise da equivalência das versões alternativas 2 e 3 e exploração do perfil de desempenho cognitivoSantiago, Joana Sofia Marques masterThesisopenAccess
4328-Nov-2019Evaluation of Human Cerebrospinal Fluid Malate Dehydrogenase 1 as a Marker in Genetic Prion Disease PatientsZerr, Inga; Villar-Piqué, Anna; Schmitz, Vanda Edit; Poleggi, Anna; Pocchiari, Maurizio; Sánchez-Valle, Raquel ; Calero, Miguel; Calero, Olga; Baldeiras, Inês ; Santana, Isabel ; Kovacs, Gabor G.; Llorens, Franc; Schmitz, MatthiasarticleopenAccess
4411-Aug-2020Face-Specific Perceptual Distortions Reveal A View- and Orientation-Independent Face TemplateAlmeida, Jorge ; Freixo, Andreia ; Tábuas-Pereira, Miguel ; Herald, Sarah B.; Valério, Daniela ; Schu, Guilherme ; Duro, Diana ; Cunha, Gil ; Bukhari, Qasim; Duchaine, Brad; Santana, Isabel articleopenAccess
452004Frontotemporal dementia and mitochondrial DNA transitionsGrazina, Manuela ; Silva, Filipe ; Santana, Isabel ; Santiago, Beatriz ; Mendes, Cândida ; Simões, Marta; Oliveira, Miguel ; Cunha, Luís ; Oliveira, Catarina articleopenAccess
462006Genetic basis of Alzheimer's dementia: role of mtDNA mutationsGrazina, M. ; Pratas, J. ; Silva, F. ; Oliveira, S. ; Santana, I. ; Oliveira, C. articleopenAccess
472023Genetic forms of primary progressive aphasia within the GENetic Frontotemporal dementia Initiative (GENFI) cohort: comparison with sporadic primary progressive aphasiaSamra, Kiran; MacDougall, Amy M.; Bouzigues, Arabella; Bocchetta, Martina; Cash, David M.; Greaves, Caroline V.; Convery, Rhian S.; Hardy, Chris; van Swieten, John C.; Seelaar, Harro; Jiskoot, Lize C.; Moreno, Fermin; Sánchez-Valle, Raquel ; Laforce, Robert; Graff, Caroline; Masellis, Mario; Tartaglia, Maria Carmela; Rowe, James B.; Borroni, Barbara; Finger, Elizabeth; Synofzik, Matthis; Galimberti, Daniela; Vandenberghe, Rik; de Mendonça, Alexandre; Butler, Chris R.; Gerhard, Alexander; Ducharme, Simon; Le Ber, Isabelle; Santana, Isabel ; Pasquier, Florence; Levin, Johannes; Otto, Markus; Sorbi, Sandro; Warren, Jason D.; Rohrer, Jonathan D. ; Russell, Lucy L.articleopenAccess
482010Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APPGuerreiro, Rita João ; Baquero, Miquel ; Blesa, Rafael ; Boada, Mercè ; Brás, José Miguel ; Bullido, Maria. J. ; Calado, Ana ; Crook, Richard ; Ferreira, Carla; Frank, Ana ; Gómez-Isla, Teresa ; Hernández, Isabel ; Lleó, Alberto ; Machado, Álvaro ; Martínez- Lage, Pablo ; Masdeu, José ; Molina-Porcel, Laura ; Molinuevo, José L. ; Pastor, Pau ; Pérez-Tur, Jordi ; Relvas, Rute ; Oliveira, Catarina Resende ; Ribeiro, Maria Helena ; Rogaeva, Ekaterina ; Sá, Alfredo ; Samaranch, Lluís ; Sánchez-Valle, Raquel ; Santana, Isabel ; Tàrraga, Lluís ; Valdivieso, Fernando ; Singleton, Andrew ; Hardy, John ; Clarimón, Jordi articleopenAccess
493-Mar-2010Genetic Variability in CLU and Its Association with Alzheimer's DiseaseGuerreiro, Rita J. ; Beck, John ; Gibbs, J. Raphael ; Santana, Isabel ; Rossor, Martin N. ; Schott, Jonathan M. ; Nalls, Michael A. ; Ribeiro, Helena ; Santiago, Beatriz ; Fox, Nick C. ; Oliveira, Catarina ; Collinge, John ; Mead, Simon ; Singleton, Andrew ; Hardy, John articleopenAccess
50May-2011Glaucoma e doença de AlzheimerBrito, Sergio Filipe Seco da Silva masterThesisopenAccess
512023Hemispheric Patterns of Recruitment of Object Processing Regions in Early Alzheimer's Disease: A Study Along the Entire Ventral StreamCanário, Nádia ; Jorge, Lília P. ; Santana, Isabel J. ; Castelo-Branco, Miguel articleopenAccess
526-Mar-2019Impact of vitamin D in patients with epilepsySaraiva, Ana Margarida RajãomasterThesisembargoedAccess
532021Impairment of episodic memory in genetic frontotemporal dementia: A GENFI studyPoos, Jackie M; Russell, Lucy L; Peakman, Georgia; Bocchetta, Martina; Greaves, Caroline V; Jiskoot, Lize C; van der Ende, Emma L; Seelaar, Harro; Papma, Janne M; van den Berg, Esther; Pijnenburg, Yolande A L; Borroni, Barbara; Sánchez-Valle, Raquel ; Moreno, Fermin; Laforce, Robert; Graff, Caroline; Synofzik, Matthias; Galimberti, Daniela; Rowe, James B; Masellis, Mario; Tartaglia, Carmela; Finger, Elizabeth; Vandenberghe, Rik; de Medonça, Alexandre; Tagliavini, Fabrizio ; Butler, Chris R; Santana, Isabel ; Ber, Isabelle Le; Gerhard, Alex; Ducharme, Simon; Levin, Johannes; Danek, Adrian; Otto, Markus; Sorbi, Sandro; Pasquier, Florence; van Swieten, John C; Rohrer, Jonathan D. articleopenAccess
5417-Nov-2020Increased C-X-C Motif Chemokine Ligand 12 Levels in Cerebrospinal Fluid as a Candidate Biomarker in Sporadic Amyotrophic Lateral SclerosisAndrés-Benito, Pol; Povedano, Mònica; Domínguez, Raúl; Marco, Carla; Colomina, Maria J.; López-Pérez, Óscar; Santana, Isabel ; Baldeiras, Inês ; Martínez-Yelámos, Sergio; Zerr, Inga; Llorens, Franc; Fernández-Irigoyen, Joaquín; Santamaría, Enrique; Ferrer, IsidroarticleopenAccess
5523-Jan-2021Investigating the Spatial Associations Between Amyloid-β Deposition, Grey Matter Volume, and Neuroinflammation in Alzheimer's DiseaseJorge, Lília ; Martins, Ricardo Filipe Alves ; Canário, Nádia ; Xavier, Carolina; Abrunhosa, Antero José Pena Afonso de ; Santana, Isabel ; Castelo-Branco, Miguel articleopenAccess
562021Knowing how to do it or doing it? A double dissociation between tool-gesture production and tool-gesture knowledgeValério, Daniela ; Santana, Isabel ; Sousa, Diana Aguiar de; Schu, Guilherme ; Leal, Gabriela; Pavão Martins, Isabel; Almeida, Jorge articleembargoedAccess
57Apr-2023Language impairment in the genetic forms of behavioural variant frontotemporal dementiaSamra, Kiran; MacDougall, Amy M.; Bouzigues, Arabella; Bocchetta, Martina; Cash, David M.; Greaves, Caroline V.; Convery, Rhian S.; van Swieten, John C.; Seelaar, Harro; Jiskoot, Lize; Moreno, Fermin; Sánchez-Valle, Raquel ; Laforce, Robert; Graff, Caroline; Masellis, Mario; Tartaglia, Maria Carmela; Rowe, James B.; Borroni, Barbara; Finger, Elizabeth; Synofzik, Matthis; Galimberti, Daniela; Vandenberghe, Rik; de Mendonça, Alexandre; Butler, Christopher R.; Gerhard, Alexander; Ducharme, Simon; Le Ber, Isabelle; Tiraboschi, Pietro; Santana, Isabel ; Pasquier, Florence; Levin, Johannes; Otto, Markus; Sorbi, Sandro; Rohrer, Jonathan D. ; Russell, Lucy L; Genetic FTD Initiative (GENFI)articleopenAccess
5825-Oct-2019Lower CSF Amyloid-Beta1-42 Predicts a Higher Mortality Rate in Frontotemporal DementiaVieira, Daniela ; Durães, João; Baldeiras, Inês; Santiago, Beatriz ; Duro, Diana; Lima, Marisa ; Leitão, Maria João ; Tábuas-Pereira, Miguel ; Santana, Isabel articleopenAccess
59Mar-2012A metamemória na progressão do défice cognitivo ligeiro para a doença de AlzheimerLopes, Lisete Cachinho masterThesisopenAccess
602016MicroRNA deregulation and chemotaxis and phagocytosis impairment in Alzheimer's diseaseGuedes, Joana R. ; Santana, Isabel ; Cunha, Catarina ; Duro, Diana ; Almeida, Maria R. ; Cardoso, Ana M. ; Lima, Maria C. Pedroso de ; Cardoso, Ana L. articleopenAccess
61Apr-2016Mini-mental state examination: Avaliação dos novos dados normativos no rastreio e diagnóstico do défice cognitivoSantana, Isabel ; Duro, Diana ; Lemos, Raquel; Costa, Vanessa ; Pereira, Miguel; Simões, Mário R. ; Freitas, Sandra articleopenAccess
622004Mitochondria dysfunction of Alzheimer's disease cybrids enhances Aβ toxicityCardoso, Sandra M. ; Santana, Isabel ; Swerdlow, Russell H. ; Oliveira, Catarina R. articleopenAccess
632012Mitochondrial DNA involvement in frontotemporal lobar degeneration : analysis of sequence variants in MTND genesFernandes, Ana Sofia Cleto masterThesisopenAccess
64May-2013Mitochondrial DNA variants in complex V coding genes contributing to frontotemporal lobar degerationAbrantes, João Paulo Fernandes masterThesisopenAccess
652018Montreal Cognitive Assessment (MoCA) as a screening test for cognitive dysfunction in Multiple SclerosisFreitas, Sandra ; Batista, Sónia ; Afonso, Ana, C. ; Simões, Mário Rodrigues ; Sousa, Lívia de ; Cunha, Luís ; Santana, Isabel articleopenAccess
6617-Jul-2014Montreal Cognitive Assessment (MoCA): estudo de validação no défice cognitivo ligeiro vascularFerreira, Paulo Ricardo Alves masterThesisopenAccess
672013Montreal Cognitive Assessment (MoCA): Validation study for Mild Cognitive Impairment and Alzheimer´s DiseaseFreitas, Sandra ; Simões, Mário Rodrigues ; Alves, Lara ; Santana, Isabel articleopenAccess
68Mar-2023Motor symptoms in genetic frontotemporal dementia: developing a new module for clinical rating scalesSamra, Kiran; MacDougall, Amy M.; Peakman, Georgia; Bouzigues, Arabella; Bocchetta, Martina; Cash, David M.; Greaves, Caroline V.; Convery, Rhian S.; van Swieten, John C.; Jiskoot, Lize; Seelaar, Harro; Moreno, Fermin; Sánchez-Valle, Raquel ; Laforce, Robert; Graff, Caroline; Masellis, Mario; Tartaglia, Carmela; Rowe, James B.; Borroni, Barbara; Finger, Elizabeth; Synofzik, Matthis; Galimberti, Daniela; Vandenberghe, Rik; de Mendonça, Alexandre; Butler, Chris R.; Gerhard, Alexander; Ducharme, Simon; Le Ber, Isabelle; Tiraboschi, Pietro; Santana, Isabel ; Pasquier, Florence; Levin, Johannes; Otto, Markus; Sorbi, Sandro; Rohrer, Jonathan D. ; Russell, Lucy L.articleopenAccess
695-Jan-2023Network structure and transcriptomic vulnerability shape atrophy in frontotemporal dementiaShafiei, Golia; Bazinet, Vincent; Dadar, Mahsa; Manera, Ana L.; Collins, D. Louis; Dagher, Alain; Borroni, Barbara; Sánchez-Valle, Raquel ; Moreno, Fermin; Laforce, Robert; Graff, Caroline; Synofzik, Matthis; Galimberti, Daniela; Rowe, James B.; Masellis, Mario; Tartaglia, Maria Carmela; Finger, Elizabeth; Vandenberghe, Rik; de Mendonça, Alexandre; Tagliavini, Fabrizio ; Santana, Isabel ; Butler, Chris; Gerhard, Alex; Danek, Adrian; Levin, Johannes; Otto, Markus; Sorbi, Sandro; Jiskoot, Lize C.; Seelaar, Harro; van Swieten, John C.; Rohrer, Jonathan D. ; Misic, Bratislav; Ducharme, SimonarticleopenAccess
7022-Dec-2017Neural correlates of theory of mind impairment in multiple sclerosisBaptista, Sónia Raquel Marques doctoralThesisembargoedAccess (2 years)
71May-2023Neuropsychiatric symptoms in genetic frontotemporal dementia: developing a new module for Clinical Rating ScalesSamra, Kiran; Macdougall, Amy; Peakman, Georgia; Bouzigues, Arabella; Bocchetta, Martina; Cash, David M.; Greaves, Caroline V.; Convery, Rhian S.; van Swieten, John C.; Jiskoot, Lize C.; Seelaar, Harro; Moreno, Fermin; Sánchez-Valle, Raquel ; Laforce, Robert; Graff, Caroline; Masellis, Mario; Tartaglia, Maria Carmela; Rowe, James B.; Borroni, Barbara; Finger, Elizabeth; Synofzik, Matthis; Galimberti, Daniela; Vandenberghe, Rik; de Mendonca, Alexandre; Butler, Christopher R.; Gerhard, Alexander; Ducharme, Simon; Le Ber, Isabelle; Tiraboschi, Pietro; Santana, Isabel ; Pasquier, Florence; Levin, Johannes; Otto, Markus; Sorbi, Sandro; Rohrer, Jonathan D. ; Russell, Lucy L.articleopenAccess
72May-2021Neuropsychological features of progranulin-associated frontotemporal dementia: a nested case-control studyLima, Marisa ; Tábuas-Pereira, Miguel ; Duro, Diana ; Durães, João ; Vieira, Daniela ; Baldeiras, Inês ; Almeida, Maria do Rosário ; Santana, Isabel articleopenAccess
7313-Dec-2018Obesity as a risk factor for Alzheimer's disease: the role of adiponectinLetra, Liliana Rita Velindro doctoralThesisopenAccess
74Mar-2010ParassóniasGarcia, Ana Rita de Meira masterThesisopenAccess
752022Plasma Lipocalin 2 in Alzheimer's disease: potential utility in the differential diagnosis and relationship with other biomarkersHermann, Peter; Villar-Piqué, Anna; Schmitz, Matthias; Schmidt, Christian; Varges, Daniela; Goebel, Stefan; Bunck, Timothy; Lindemann, Hanna; Bogner, Carla; Santana, Isabel ; Baldeiras, Inês; Riggert, Joachim; Zerr, Inga; Llorens, FrancarticleopenAccess
7610-Jun-2023Population Pharmacokinetic Analysis of Perampanel in Portuguese Patients Diagnosed with Refractory EpilepsySilva, Rui ; Colom, Helena; Bicker, Joana ; Almeida, Anabela ; Silva, Ana; Sales, Francisco ; Santana, Isabel ; Falcão, Amílcar ; Fortuna, Ana articleopenAccess
7719-Jul-2017Predicting progression of mild cognitive impairment to dementia using neuropsychological data: a supervised learning approach using time windowsPereira, Telma; Lemos, Luís; Cardoso, Sandra; Silva, Dina; Rodrigues, Ana ; Santana, Isabel ; Mendonça, Alexandre de; Guerreiro, Manuela ; Madeira, Sara C.articleopenAccess
782013Premorbid IQ influence on screening tests' scores in healthy patients and patients with cognitive impairmentAlves, Lara ; Simões, Mário Rodrigues ; Martins, Cristina ; Freitas, Sandra ; Santana, Isabel articleopenAccess
7930-May-2019Presurgical Evaluation of Memory Function in Epilepsy PatientsGonçalves, Carolina Barreto RodriguesmasterThesisembargoedAccess
80Mar-2012Processamento emocional :|binfluência de variáveis demográficasAbreu, Ana Carolina Canteiro masterThesisopenAccess
8131-Oct-2014Processamento emocional no defeito cognitivo ligeiroAntunes, Bárbara Ruivo masterThesisopenAccess
8215-Aug-2023Prodromal language impairment in genetic frontotemporal dementia within the GENFI cohortSamra, Kiran; MacDougall, Amy M.; Bouzigues, Arabella; Bocchetta, Martina; Cash, David M.; Greaves, Caroline V.; Convery, Rhian S.; van Swieten, John C.; Jiskoot, Lize; Seelaar, Harro; Moreno, Fermin; Sánchez-Valle, Raquel ; Laforce, Robert; Graff, Caroline; Masellis, Mario; Tartaglia, Maria Carmela; Rowe, James B.; Borroni, Barbara; Finger, Elizabeth; Synofzik, Matthis; Galimberti, Daniela; Vandenberghe, Rik; de Mendonça, Alexandre; Butler, Chris R.; Gerhard, Alex; Ducharme, Simon; Le Ber, Isabelle; Tiraboschi, Pietro; Santana, Isabel ; Pasquier, Florence; Levin, Johannes; Otto, Markus; Sorbi, Sandro; Rohrer, Jonathan D. ; Russell, Lucy L.; Duro, Diana ; Leitão, Maria João ; Almeida, Maria do Rosário ; Afonso, Sónia articleopenAccess
8325-Apr-2016Prognosis of Early-Onset vs. Late-Onset Mild Cognitive Impairment: Comparison of Conversion Rates and Its PredictorsTábuas-Pereira, Miguel ; Baldeiras, Inês ; Duro, Diana ; Santiago, Beatriz ; Ribeiro, Maria Helena ; Leitão, Maria João ; Oliveira, Catarina ; Santana, Isabel articleopenAccess
844-Jan-2021Progression of Behavioral Disturbances and Neuropsychiatric Symptoms in Patients With Genetic Frontotemporal DementiaBenussi, Alberto; Premi, Enrico; Gazzina, Stefano; Brattini, Chiara; Bonomi, Elisa; Alberici, Antonella; Jiskoot, Lize; van Swieten, John C; Sánchez-Valle, Raquel ; Moreno, Fermin; Laforce, Robert; Graff, Caroline; Synofzik, Matthis; Galimberti, Daniela; Masellis, Mario; Tartaglia, Carmela; Rowe, James B; Finger, Elizabeth; Vandenberghe, Rik; de Mendonça, Alexandre; Tagliavini, Fabrizio ; Santana, Isabel ; Ducharme, Simon; Butler, Chris R; Gerhard, Alexander; Levin, Johannes; Danek, Adrian; Otto, Markus; Frisoni, Giovanni; Ghidoni, Roberta; Sorbi, Sandro; Le Ber, Isabelle; Pasquier, Florence; Peakman, Georgia; Todd, Emily; Bocchetta, Martina; Rohrer, Jonathan D. ; Borroni, Barbara; Afonso, Sónia ; Leitão, Maria João ; et al.articleopenAccess
852014Psychometric properties of the Montreal Cognitive Assessment (MoCA): An analysis using the Rasch modelFreitas, Sandra ; Gerardo, Prieto ; Simões, Mário Rodrigues ; Santana, Isabel articleopenAccess
862023Reconsidering the role of blood-brain barrier in Alzheimer's disease: From delivery to targetSousa, João André; Bernardes, Catarina; Bernardo-Castro, Sara ; Lino, Miguel ; Albino, Inês ; Ferreira, Lino; Brás, José ; Guerreiro, Rita; Tábuas-Pereira, Miguel ; Baldeiras, Inês ; Santana, Isabel ; Sargento-Freitas, João articleopenAccess
87Aug-2023Reduction of class I histone deacetylases ameliorates ER-mitochondria cross-talk in Alzheimer's diseaseMarinho, Daniela ; Ferreira, Ildete L. ; Lorenzoni, Ricardo ; Cardoso, Sandra M. ; Santana, Isabel ; Rego, A. Cristina articleopenAccess
8819-Feb-2015Regulação genética do receptor 5-HT2A na Demência FrontotemporalLuís, Daniela Filipa Ribeiro doctoralThesisembargoedAccess
893-Apr-2023Resective Epilepsy Surgery and Respective Histopathological Diagnoses: A Retrospective Cohort StudyJesus-Ribeiro, Joana ; Rebelo, Olinda ; Bento, Conceição; Pereira, Cristina Maria Gonçalves ; Robalo, Conceição ; Rito, Manuel; Pereira, Ricardo; Costa, José Augusto; Melo, Joana Barbosa ; Freire, António ; Santana, Isabel ; Sales, Francisco articleopenAccess
902019Retinal texture biomarkers may help to discriminate between Alzheimer's, Parkinson's, and healthy controlsNunes, Ana ; Silva, Gilberto ; Duque, Cristina; Januário, Cristina ; Santana, Isabel ; Ambrósio, António ; Castelo-Branco, Miguel ; Bernardes, Rui articleopenAccess
912015Scaling cognitive domains of the Montreal Cognitive Assessment (MoCA): An analysis using the Partial Credit ModelFreitas, Sandra ; Prieto, Gerardo ; Simões, Mário Rodrigues ; Santana, Isabel articleopenAccess
922019Semi-quantification and grading of amyloid PET: A project of the European Alzheimer's Disease Consortium (EADC)Chincarini, A.; Peira, E.; Morbelli, S.; Pardini, M.; Bauckneht, M.; Arbizu, J.; Castelo-Branco, Miguel ; Büsing, K. A.; de Mendonça, A.; Didic, M.; Dottorini, M.; Engelborghs, S.; Ferrarese, C.; Frisoni, G. B.; Garibotto, V.; Guedj, E.; Hausner, L.; Hugon, J.; Verhaeghe, J.; Mecocci, P.; Musarra, M.; Queneau, M.; Riverol, M.; Santana, Isabel ; Guerra, U. P.; Nobili, F.articleopenAccess
932013TeLPI Performance in subjects with Mild Cognitive Impairment and Alzheimer`s Disease: A validation studyAlves, Lara ; Simões, Mário Rodrigues ; Martins, Cristina ; Freitas, Sandra ; Santana, Isabel articleopenAccess
94May-2023Temporal dynamics predict symptom onset and cognitive decline in familial frontotemporal dementiaWhiteside, David J.; Malpetti, Maura; Jones, P Simon; Ghosh, Boyd C. P.; Coyle-Gilchrist, Ian; van Swieten, John C.; Seelaar, Harro; Jiskoot, Lize; Borroni, Barbara; Sánchez-Valle, Raquel ; Moreno, Fermin; Laforce, Robert; Graff, Caroline; Synofzik, Matthis; Galimberti, Daniela; Masellis, Mario; Tartaglia, Maria Carmela; Finger, Elizabeth; Vandenberghe, Rik; de Mendonça, Alexandre; Tagliavini, Fabrizio ; Butler, Chris R.; Santana, Isabel ; Ber, Isabelle Le; Gerhard, Alexander; Ducharme, Simon; Levin, Johannes; Danek, Adrian; Otto, Markus; Sorbi, Sandro; Pasquier, Florence; Bouzigues, Arabella; Russell, Lucy L.; Rohrer, Jonathan D. ; Rowe, James B.; Rittman, TimothyarticleopenAccess
952022The Assessment of Cognitive Reserve: A Systematic Review of the Most Used Quantitative Measurement Methods of Cognitive Reserve for AgingNogueira, Joana ; Gerardo, Bianca Salguinho ; Santana, Isabel ; Simões, Mário R. ; Freitas, Sandra articleopenAccess
9615-Mar-2023The Benson Complex Figure Test detects deficits in visuoconstruction and visual memory in symptomatic familial frontotemporal dementia: A GENFI studyJiskoot, Lize C.; Russell, Lucy L.; Peakman, Georgia; Convery, Rhian S.; Greaves, Caroline V.; Bocchetta, Martina; Poos, Jackie M.; Seelaar, Harro; Giannini, Lucia A. A.; van Swieten, John C.; van Minkelen, Rick; Pijnenburg, Yolande A. L.; Rowe, James B.; Borroni, Barbara; Galimberti, Daniela; Masellis, Mario; Tartaglia, Carmela; Finger, Elizabeth; Butler, Chris R.; Graff, Caroline; Laforce, Robert; Sánchez-Valle, Raquel ; de Mendonça, Alexandre; Moreno, Fermin; Synofzik, Matthis; Vandenberghe, Rik; Ducharme, Simon; le Ber, Isabelle; Levin, Johannes; Otto, Markus; Pasquier, Florence; Santana, Isabel ; Cash, David M.; Thomas, David; Rohrer, Jonathan D. articleopenAccess
977-Apr-2021The Clock Drawing Test in the detection of cognitive impairment: Validation studies for the Portuguese populationDuro, Diana Filipa Dias doctoralThesisembargoedAccess
982018The Quadruple Helix-Based Innovation Model of Reference Sites for Active and Healthy Ageing in Europe: The Ageing@Coimbra Case StudyMalva, João O. ; Amado, Alda ; Rodrigues, Alexandra; Mota-Pinto, Anabela ; Cardoso, Ana F.; Teixeira, Ana M. ; Todo-Bom, Ana ; Devesa, António; Ambrósio, António ; Cunha, António L.; Gomes, Bárbara ; Dantas, Carina; Abreu, Cidalina ; Santana, Isabel ; Bousquet, Jean ; Apóstolo, João ; Santos, Lúcia; Meneses de Almeida, Lúcio; Illario, Maddalena; Veríssimo, Rafaela ; Rodrigues, Vitor ; Veríssimo, Manuel T. articleopenAccess
992015The relevance of sociodemographic and health variables on MMSE normative dataFreitas, Sandra ; Simões, Mário Rodrigues ; Alves, Lara ; Santana, Isabel articleopenAccess
1002020The Retinal Inner Plexiform Synaptic Layer Mirrors Grey Matter Thickness of Primary Visual Cortex with Increased Amyloid β Load in Early Alzheimer's DiseaseJorge, Lília; Canário, Nádia; Martins, Ricardo ; Santiago, Beatriz ; Santana, Isabel ; Quental, Hugo ; Ambrósio, Francisco ; Bernardes, Rui ; Castelo-Branco, Miguel articleopenAccess
1012021The Revised Self-Monitoring Scale detects early impairment of social cognition in genetic frontotemporal dementia within the GENFI cohortFranklin, Hannah D; Russell, Lucy L; Peakman, Georgia; Greaves, Caroline V; Bocchetta, Martina; Nicholas, Jennifer; Poos, Jackie; Convery, Rhian S; Cash, David M; van Swieten, John; Jiskoot, Lize; Moreno, Fermin; Santana, Isabel ; Almeida, M. R.; Afonso, S.articleopenAccess
10229-Jan-2022The Road to Personalized Medicine in Alzheimer's Disease: The Use of Artificial IntelligenceSilva-Spínola, Anuschka; Baldeiras, Inês E. ; Arrais, Joel P. ; Santana, Isabel articleopenAccess
10320-Sep-2018Toulouse-Piéron Cancellation Test: Validation and normalization studies in cognitive declineNeves, Marisa Pedroso de Lima Marta masterThesisembargoedAccess
104Oct-2014Validation studies of the clock drawing test in mild cognitive impairmentCarneiro, Diogo Fernando Reis masterThesisopenAccess
10522-Mar-2016Verbal Memory and Visual Perception in early Alzheimer’s disease: Contribution of new diagnostic tools for new classification criteriaOliveira, Raquel Maria Baptista Lemos Guerra de doctoralThesisopenAccess
10630-Oct-2018Visuoconstructional impairment in Mild Cognitive Impairment: Diagnostic utility and predictive value in the progression to Alzheimer’s diseaseGerardo, Bianca Salguinho masterThesisopenAccess
1072019White matter hyperintensities in progranulin-associated frontotemporal dementia: A longitudinal GENFI studySudre, Carole H.; Bocchetta, Martina; Heller, Carolin; Convery, Rhian; Neason, Mollie; Moore, Katrina M.; Cash, David M.; Thomas, David L.; Woollacott, Ione O. C.; Foiani, Martha; Heslegrave, Amanda; Shafei, Rachelle; Greaves, Caroline; van Swieten, John; Moreno, Fermin; Sánchez-Valle, Raquel ; Borroni, Barbara; Laforce, Robert; Masellis, Mario; Tartaglia, Maria Carmela; Graff, Caroline; Galimberti, Daniela; Rowe, James B; Finger, Elizabeth; Synofzik, Matthis; Vandenberghe, Rik; de Mendonça, Alexandre; Tagliavini, Fabrizio ; Santana, Isabel ; Ducharme, Simon; Butler, Chris; Gerhard, Alex; Levin, Johannes; Danek, Adrian; Frisoni, Giovanni B; Sorbi, Sandro; Otto, Markus; Zetterberg, Henrik; Ourselin, Sebastien; Cardoso, M Jorge; Rohrer, Jonathan D. articleopenAccess