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Credit Name
Sousa, Hermínio C. de
 
Name
Sousa, Herminio C. de
 
Variants
de Sousa, Herminio
de Sousa, H.C.
Sousa, H.C. de
Sousa, Hermínio José Cipriano de
 
 
Email
hsousa@eq.uc.pt
 
 
Scopus Author ID
 
Researcher ID
 
Status
UC Researcher
Biography
Hermínio C. de Sousa (HC de Sousa) graduated in Chemical Engineering (5-years Lic. Chem Eng, 1992) from the New University of Lisbon, Portugal. He completed his PhD in 1997, in Chemistry - Physical Chemistry, also at the New University of Lisbon. At the same year he got a Teaching Assistant position at the Chemical Engineering Department, University of Coimbra, Portugal (DEQ-FCTUC), where he currently holds a Tenured Associate Professor position since 2019. He is a Senior Member of the Portuguese Association of Engineers (Portugal) and of the American Institute of Chemical Engineers (AIChE), USA. HC de Sousa has more than 20 years of academic experience in teaching theoretical, theoretical-practical, laboratorial and tutorial/supervision classes at the BSc, MSc and PhD levels. He was also a Visiting Professor/Researcher at the University of Massachusetts-Amherst, USA (2007, 2014), Federal University of Pará, Brazil (2009), UNICAMP, Brazil (2011, 2012), Federal University of Bahia, Brazil (2016, 2017, 2018, 2019), and National University of Colombia, Colombia (2013, 2014, 2017). HC de Sousa is the team leader of the Green and Sustainable Processes Laboratory (GSP), at the Chemical Process Engineering and Forest Products Research Centre of the Chemical Engineering Department of the University of Coimbra (CIEPQPF/DEQ-FCTUC). GSP research strategies and activities are mainly focused on the use of “greener”, sustainable, safer, biomimetic and environmentally-friendly innovative processes for the development of value-added products and materials/nanomaterials which are predominantly envisaged for pharmaceutical/drug delivery and biomedical/tissue engineering applications. However, food, agricultural, nutraceutical, cosmetic, antimicrobial, water treatment, oil & gas, electronics, and low VOC-emission materials/applications are/were also covered. Employed “greener” and sustainable approaches comprise the use of supercritical fluids (e.g., high-pressure, subcritical and supercritical carbon dioxide); of aqueous/ethanolic-based solvent systems; of natural-origin biopolymers and phytochemicals obtained from renewable resources (e.g., from vegetable raw materials and agro-industrial residues/wastes); of ionic liquids (namely of safer/biodegradable ionic liquids), and of “greener”, biomimetic and self-assembly-based synthesis/processing strategies. Several advantageous combinations of these five approaches were/are also implemented. Specific examples of application of the GSP research activities include the development of: nano/microparticles for drug delivery; implants, hydrogels and contact/intraocular lenses for ophthalmic drug delivery; medicated natural-origin wound dressings (namely for diabetic foot ulceration treatment); pre-formed and in-situ forming polymeric implants for prolonged drug/protein release; natural-origin adhesives and bioadhesives; bioactive natural products and their pharmaceutical/biomedical, food, nutraceutical, agricultural and cosmetic formulations/delivery systems; natural-origin flocculants for water treatment; plasticized low-VOC emission PVC/PU materials; and macro-, meso- and microporous silica-based biomaterials (e.g., biomimetic/bioactive biopolymer/silica composite/hybrid biomaterials - drug delivery/hard-tissue applications). More recent research topics include the development of: 1) multifunctional stimuli-responsive and electroactive biomaterials; 2) novel and more efficient materials and nanomaterials for oxygen/CO2/gas capture, storage, delivery and separation; 3) enhanced oil recovery and CO2/water-induced asphaltene precipitation in crude oil reservoirs; 4) improved and eco-friendly agricultural pesticide delivery, biomanagement and pest control (namely for insects/nematodes control); 5) supercritical CO2 as a sterilizing and biocidal agent.
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Publications
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Author:  Sousa, Hermínio C. de

Results 1-40 of 40 (Search time: 0.026 seconds).

Issue DateTitleAuthor(s)TypeAccess
1Feb-2014Chitosan-based dressings loaded with neurotensin—an efficient strategy to improve early diabetic wound healingMoura, Liane I. F. ; Dias, Ana M. A. ; Leal, Ermelindo C. ; Carvalho, Lina ; Sousa, Hermínio C. de ; Carvalho, Eugénia articleopenAccess
22022Chitosan-xanthan gum PEC-based aerogels: A chemically stable PEC in scCO2Tomé, Luciana I. N. ; Reis, Marco S. ; Sousa, Hermínio C. de ; Braga, Mara E. M. articleembargoedAccess
3Nov-2014Control of the properties of porous chitosan-alginate membranes through the addition of different proportions of Pluronic F68Bueno, Cecilia Zorzi ; Dias, Ana Maria Antunes ; Sousa, Hermínio José Cipriano de ; Braga, Mara Elga Medeiros ; Moraes, Angela Maria articleopenAccess
418-Nov-2013Dexamethasone-loaded poly(ε-caprolactone)/silica nanoparticles composites prepared by supercritical CO2 foaming/mixing and depositionMatos, M. B. C. de ; Piedade, A. P. ; Alvarez-Lorenzo, C. ; Concheiro, A. ; Braga, M. E. M. ; Sousa, H. C. de articleopenAccess
526-Feb-2002Double Critical Phenomena in (Water + Polyacrylamides) SolutionsRebelo, L. P. N. ; Visak, Z. P. ; Sousa, H. C. de ; Szydlowski, J. ; Azevedo, R. Gomes de ; Ramos, A. M. ; Najdanovic-Visak, V. ; Ponte, M. Nunes da ; Klein, J. articleopenAccess
6Sep-2010Effects of drug solubility, state and loading on controlled release in bicomponent electrospun fibersNatu, Mădălina V. ; Sousa, Hermínio C. de ; Gil, M. H. articleopenAccess
72014Effects of Two Phosphonium-Type Ionic Liquids on the Rheological and Thermomechanical Properties of Emulsion Poly(vinyl chloride)-Based Formulations Plasticized with DINP and CITROFOLMarceneiro, Sofia ; Hu, Qingyun ; Dias, Ana M. A. ; Lobo, Irene ; Dias, Isabel ; Pinho, Elizabete de ; Rasteiro, M. Graça ; Sousa, Hermínio C. de articleopenAccess
82011Electrospun Drug-Eluting Fibers for Biomedical ApplicationsNatu, Mădălina V. ; Sousa, Hermínio C. de ; Gil, Maria H. bookPartopenAccess
92020Environmentally-safe scCO2 P. pinaster branches extracts: Composition and propertiesGaspar, Marisa C. ; Sousa, Hermínio C. de ; Seabra, Inês J. ; Braga, Mara E. M. articleembargoedAccess
1011-May-2006Experimental Determination and Correlation of Artemisinin's Solubility in Supercritical Carbon DioxideCoimbra, Patrícia ; Blanco, Miguel R. ; Silva, Hélio S. R. Costa ; Gil, Maria H. ; Sousa, Hermínio C. de articleopenAccess
1128-Aug-2008Fractioned High Pressure Extraction of Anthocyanins from Elderberry ( Sambucus nigra L.) PomaceSeabra, Inês J. ; Braga, Mara E. M. ; Batista, Maria T. P. ; Sousa, Hermínio C. de articleopenAccess
122020Impact of the pinewood nematode on naturally-emitted volatiles and scCO2 extracts from Pinus pinaster branches: a comparison with P. pineaGaspar, M. C. ; Agostinho, B.; Fonseca, L.; Abrantes, I. ; Sousa, H. C. de ; Braga, M. E. M. articleembargoedAccess
1315-Feb-2014Impregnation of cinnamaldehyde into cassava starch biocomposite films using supercritical fluid technology for the development of food active packagingSouza, Ana Cristina de ; Dias, Ana M. A. ; Sousa, Hermínio C. ; Tadini, Carmen C. articleopenAccess
14Aug-2014Improving cell adhesion: development of a biosensor for cell behaviour monitoring by surface grafting of sulfonic groups onto a thermoplastic polyurethaneAlves, P ; Pinto, S. ; Ferreira, P. ; Kaiser, Jean-Pierre ; Bruinink, Arie ; Sousa, Hermínio C. de ; Gil, M. H. articleopenAccess
15Jul-2011In vitro and in vivo evaluation of an intraocular implant for glaucoma treatmentNatu, Mădălina V. ; Gaspar, Manuel N. ; Ribeiro, Carlos A. Fontes ; Cabrita, António M. ; Sousa, Hermínio C. de ; Gil, M. H. articleopenAccess
162013Influence of natamycin loading methods on the physical characteristics of alginate active filmsBierhalz, Andrea C.K. ; Silva, Mariana A. da ; Sousa, Hermínio C. de ; Braga, Mara E. M. ; Kieckbusch, Theo G. articleopenAccess
17Jan-2013Influence of polymer processing technique on long term degradation of poly(ε-caprolactone) constructsNatu, Mădălina V. ; Sousa, Hermínio C. de ; Gil, M. H. articleopenAccess
18Jan-2014Neurotensin-loaded collagen dressings reduce inflammation and improve wound healing in diabetic miceMoura, Liane I. F. ; Dias, Ana M. A. ; Suesca, Edward ; Casadiegos, Sergio ; Leal, Ermelindo C. ; Fontanilla, Marta R. ; Carvalho, Lina ; Sousa, Hermínio C. de ; Carvalho, Eugénia articleopenAccess
1928-Mar-2023Novel Oxygen- and Curcumin-Laden Ionic Liquid@Silica Nanocapsules for Enhanced Antimicrobial Photodynamic TherapyHenriques, Joana F. ; Pina, João ; Braga, Mara E. M. ; Dias, Ana M. A. ; Coimbra, Patrícia ; Sousa, Herminio C. de articleopenAccess
201-Feb-2015Osteogenic poly(ε-caprolactone)/poloxamine homogeneous blends prepared by supercritical foamingMatos, Maria B. C. de ; Puga, Ana M. ; Alvarez-Lorenzo, Carmen ; Concheiro, Angel ; Braga, Mara E. M. ; Sousa, Hermínio C. de articleopenAccess
212001Phase behavior of (polyacrylamides + water) solutions: concentration, pressure and isotope effectsAzevedo, R. Gomes de ; Rebelo, L. P. N. ; Ramos, A. M. ; Szydlowski, J. ; Sousa, H. C. de ; Klein, J. articleopenAccess
222011A poly(ε-caprolactone) device for sustained release of an anti-glaucoma drugNatu, Mădălina V. ; Gaspar, Manuel N. ; Ribeiro, Carlos A. Fontes ; Correia, Ilídio J. ; Silva, Daniela ; Sousa, Hermínio C. de ; Gil, M. H. articleclosedAccess
239-Nov-2019Porous poly(ε-caprolactone) implants: A novel strategy for efficient intraocular drug deliveryBoia, Raquel ; Dias, Paulo A. N.; Martins, Joana M.; Galindo-Romero, Caridad; Aires, Inês D. ; Vidal-Sanz, Manuel; Agudo-Barriuso, Marta; Sousa, Hermínio C. de ; Ambrósio, António Francisco ; Braga, Mara E. M. ; Santiago, Ana Raquel articleopenAccess
242008Preparation and characterization of flurbiprofen-loaded poly(3-hydroxybutyrate-co-3-hydroxyvalerate) microspheresCoimbra, Patrícia A. ; Sousa, Hermínio C. de ; Gil, Maria H. articleopenAccess
2520-Nov-2003Pressure, Isotope, and Water Co-solvent Effects in Liquid−Liquid Equilibria of (Ionic Liquid + Alcohol) SystemsNajdanovic-Visak, Vesna ; Esperança, José M. S. S. ; Rebelo, Luís P. N. ; Ponte, Manuel Nunes da ; Guedes, Henrique J. R. ; Seddon, Kenneth R. ; Sousa, Hermínio C. de ; Szydlowski, Jerzy articleopenAccess
26Jul-2013Recent advances on the development of wound dressings for diabetic foot ulcer treatment--a reviewMoura, Liane I. F. ; Dias, Ana M. A. ; Carvalho, Eugénia ; Sousa, Hermínio C. de articleopenAccess
2713-Jan-2005Solubility of Acetazolamide in Supercritical Carbon Dioxide in the Presence of Ethanol as a CosolventDuarte, Ana Rita C. ; Santiago, Susana ; Sousa, Hermínio C. de ; Duarte, Catarina M. M. articleopenAccess
282015Solubility of all-trans retinoic acid in supercritical carbon dioxideRosa, António B. S. ; Marceneiro, Sofia ; Braga, Mara E. M. ; Dias, Ana M. A. ; Sousa, Hermínio C. de articleopenAccess
292006Solubility of dense CO2 in two biocompatible acrylate copolymersDuarte, A. R. C.; Sousa, A. R. Sampaio de; Sousa, H. C. de ; Gil, M. H. M. ; Jespersen, H. T.; Duarte, C. M. M.articleopenAccess
3014-Aug-2008Solubility of Diflunisal in Supercritical Carbon DioxideCoimbra, Patrícia ; Fernandes, Daniel ; Gil, Maria H. ; Sousa, Hermínio C. de articleopenAccess
3113-May-2004Solubility of Flurbiprofen in Supercritical Carbon DioxideDuarte, Ana Rita C. ; Coimbra, Patrícia ; Sousa, Hermínio C. de ; Duarte, Catarina M. M. articleopenAccess
322008Solubility of Irgacure® 2959 photoinitiator in supercritical carbon dioxide: Experimental determination and correlationCoimbra, Patrícia ; Fernandes, Daniel ; Ferreira, Paula ; Gil, Maria H. ; Sousa, Hermínio C. de articleopenAccess
332006Sorption and diffusion of dense carbon dioxide in a biocompatible polymerDuarte, Ana Rita C. ; Martins, Carlos ; Coimbra, Patrícia ; Gil, Maria H. M. ; Sousa, Hermínio C. de ; Duarte, Catarina M. M. articleopenAccess
342007Supercritical fluid impregnation of a biocompatible polymer for ophthalmic drug deliveryDuarte, Ana Rita C. ; Simplicio, Ana Luísa ; Vega-González, Arlette ; Subra-Paternault, Pascale ; Coimbra, Patrícia ; Gil, M. H. ; Sousa, Hermínio C. de ; Duarte, Catarina M. M. articleopenAccess
352008Supercritical solvent impregnation of ophthalmic drugs on chitosan derivativesBraga, Mara E. M. ; Pato, Maria T. Vaz ; Silva, Hélio S. R. Costa ; Ferreira, Elisabeth I. ; Gil, Maria H. ; Duarte, Catarina M. M. ; Sousa, Hermínio C. de articleopenAccess
36Nov-2008Supercritical solvent impregnation of poly(ɛ-caprolactone)/poly(oxyethylene-b-oxypropylene-b-oxyethylene) and poly(ɛ-caprolactone)/poly(ethylene-vinyl acetate) blends for controlled release applicationsNatu, Mădălina V. ; Gil, M. H. ; Sousa, Hermínio C. de articleopenAccess
3715-Oct-2013Surface grafting of carboxylic groups onto thermoplastic polyurethanes to reduce cell adhesionAlves, P. ; Ferreira, P. ; Kaiser, Jean-Pierre ; Salk, Natalie ; Bruinink, Arie ; Sousa, Hermínio C. de ; Gil, M. H. articleopenAccess
382023Transcriptome analysis reveals the high ribosomal inhibitory action of 1,4-naphthoquinone on Meloidogyne luci infective second-stage juvenilesCardoso, Joana M. S. ; Esteves, Ivânia ; Egas, Conceição ; Braga, Mara E. M. ; Sousa, Herminio C. de ; Abrantes, Isabel ; Maleita, Carla articleopenAccess
3915-Sep-2021Using High-Pressure Technology to Develop Antioxidant-Rich Extracts from Bravo de Esmolfe Apple ResiduesBordalo, Mário; Seabra, Inês J. ; Silva, Andreia Bento; Terrasso, Ana Paula; Brito, Catarina ; Serra, Margarida; Bronze, Maria R.; Duarte, Catarina M. M. ; Braga, Mara E. M. ; de Sousa, Herminio C. ; Serra, Ana TeresaarticleopenAccess
402013Wound dressings loaded with an anti-inflammatory jucá (Libidibia ferrea) extract using supercritical carbon dioxide technologyDias, A.M.A. ; Rey-Rico, A. ; Oliveira, R.A. ; Marceneiro, S. ; Alvarez-Lorenzo, C. ; Concheiro, A. ; Júnior, R.N.C. ; Braga, M. E. M. ; Sousa, H.C. de articleopenAccess