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Gonçalves, Nélio
 
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Issue DateTitleAuthor(s)TypeAccess
130-Jan-2013Activation of microglial cells triggers a release of brain-derived neurotrophic factor (BDNF) inducing their proliferation in an adenosine A2A receptor-dependent manner: A2A receptor blockade prevents BDNF release and proliferation of microgliaGomes, Catarina ; Ferreira, Raquel ; George, Jimmy ; Sanches, Rui; Rodrigues, Diana I. ; Gonçalves, Nélio ; Cunha, Rodrigo A. articleopenAccess
22015Adenosine A2A recepto rs role in stress-induced neurobiological modificationsFernandes, Sara Beatriz Gomes masterThesisopenAccess
32018Adenosine A2A Receptors in the Rat Prelimbic Medial Prefrontal Cortex Control Delay-Based Cost-Benefit Decision MakingLeffa, Douglas T; Pandolfo, Pablo; Gonçalves, Nélio ; Machado, Nuno J. ; de Souza, Carolina M; Real, Joana I. ; Silva, Antonio C. ; Silva, Henrique B. ; Köfalvi, Attila ; Cunha, Rodrigo A. ; Ferreira, Samira G. articleopenAccess
4Jun-2016Astrocytic A2A receptors : novel targets to manage brain disordersHenriques, Vanessa Jorge masterThesisembargoedAccess
52013Caffeine and adenosine A 2A receptor inactivation decrease striatal neuropathology in a lentiviral-based model of Machado–Joseph diseaseGonçalves, Nélio ; Simões, Ana T. ; Cunha, Rodrigo A. ; Almeida, Luís Pereira de articleopenAccess
62014Calpain inhibition reduces ataxin-3 cleavage alleviating neuropathology and motor impairments in mouse models of Machado-Joseph diseaseSimões, Ana Teresa ; Gonçalves, Nélio ; Nobre, Rui Jorge ; Duarte, Carlos Bandeira ; Almeida, Luís Pereira de articleembargoedAccess
72012Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado–Joseph diseaseSimões, Ana T. ; Gonçalves, Nélio ; Koeppen, Arnulf ; Déglon, Nicole ; Kügler, Sebastian ; Duarte, Carlos Bandeira ; Almeida, Luís Pereira de articleopenAccess
813-Jan-2021Cancer Stem Cells and Nucleolin as Drivers of CarcinogenesisCarvalho, Laura Sofia ; Gonçalves, Nélio ; Fonseca, Nuno André ; Moreira, João Nuno articleopenAccess
92015Depression as a Glial-Based Synaptic DysfunctionRial, Daniel ; Lemos, Cristina ; Pinheiro, Helena ; Duarte, Joana M. ; Gonçalves, Francisco Q. ; Real, Joana I. ; Prediger, Rui D.; Gonçalves, Nélio ; Gomes, Catarina A. ; Canas, Paula M. ; Agostinho, Paula articleopenAccess
1017-Jun-2016Early synaptic deficits in the APP/PS1 mouse model of Alzheimer's disease involve neuronal adenosine A2A receptorsSilva, Sílvia Viana da ; Haberl, Matthias Georg; Zhang, Pei; Bethge, Philipp; Lemos, Cristina ; Gonçalves, Nélio ; Gorlewicz, Adam; Malezieux, Meryl; Gonçalves, Francisco Q. ; Grosjean, Noëlle; Blanchet, Christophe; Frick, Andreas; Nägerl, U Valentin; Cunha, Rodrigo A. ; Mulle, Christophe articleopenAccess
1129-Nov-2013Gene transfer approaches to study the role of adenosine A2A receptors in Machado-Joseph diseaseGonçalves, Nélio da Mota doctoralThesisopenAccess
12Apr-2021GMP-grade nanoparticle targeted to nucleolin downregulates tumor molecular signature, blocking growth and invasion, at low systemic exposureFonseca, Nuno A.; Gregório, Ana C.; Mendes, Vera M.; Lopes, Rui; Abreu, Teresa ; Gonçalves, Nélio ; Manadas, Bruno ; Lacerda, Manuela ; Figueiredo, Paulo; Pereira, Marta; Gaspar, Manuela; Colelli, Fabiana; Pesce, Daniela; Signorino, Giacomo; Focareta, Laura; Fucci, Alessandra; Cardile, Francesco; Pisano, Claudio; Cruz, Tony ; Almeida, Luís; Moura, Vera ; Simões, Sérgio; Moreira, João N. articleembargoedAccess
13Sep-2021Increased ATP release and CD73-mediated adenosine A2A receptor activation mediate convulsion-associated neuronal damage and hippocampal dysfunctionAugusto, Elisabete de Oliveira ; Gonçalves, Francisco Q.; Real, Joana E. ; Silva, Henrique B.; Pochmann, Daniela ; Silva, Tiago S.; Matos, Marco; Gonçalves, Nélio da Mota ; Tomé, Ângelo R. ; Chen, Jiang-Fan ; Canas, Paula M.; Cunha, Rodrigo A. articleopenAccess
14Mar-2023Increased ATP Release and Higher Impact of Adenosine A2A Receptors on Corticostriatal Plasticity in a Rat Model of Presymptomatic Parkinson's DiseaseGonçalves, Francisco Q. ; Matheus, Filipe C.; Silva, Henrique B. ; Real, Joana I. ; Rial, Daniel ; Rodrigues, Ricardo J. ; Oses, Jean-Pierre; Silva, Antonio C. ; Gonçalves, Nélio ; Prediger, Rui D.; Tomé, Ângelo R. ; Cunha, Rodrigo A. articleopenAccess
155-Apr-2023Increased Synaptic ATP Release and CD73-Mediated Formation of Extracellular Adenosine in the Control of Behavioral and Electrophysiological Modifications Caused by Chronic StressDias, Liliana ; Pochmann, Daniela ; Lemos, Cristina ; Silva, Henrique B. ; Real, Joana I. ; Gonçalves, Francisco Q. ; Rial, Daniel ; Gonçalves, Nélio ; Simões, Ana Patrícia ; Ferreira, Samira G. ; Agostinho, Paula M. ; Cunha, Rodrigo A. ; Tomé, Ângelo R. articleopenAccess
162018Neuronal Adenosine A2A Receptors Are Critical Mediators of Neurodegeneration Triggered by ConvulsionsCanas, Paula M. ; Porciúncula, Lisiane O. ; Simões, Ana Patrícia ; Augusto, Elisabete de Oliveira ; Silva, Henrique B. ; Machado, Nuno J. ; Gonçalves, Nélio ; Alfaro, Tiago M. ; Gonçalves, Francisco Q. ; Araújo, Inês M. ; Real, Joana I. ; Coelho, Joana E. ; Andrade, Geanne M. ; Almeida, Ramiro D. ; Chen, Jiang-Fan ; Köfalvi, Attila ; Agostinho, Paula ; Cunha, Rodrigo A. articleopenAccess
1729-Apr-2022Nucleolin Overexpression Predicts Patient Prognosis While Providing a Framework for Targeted Therapeutic Intervention in Lung CancerFernandes, Ângela Valério ; Fonseca, Nuno A. ; Gonçalves, Nélio ; Cruz, Ana F. ; Pereira, Marta I. ; Gregório, Ana C. ; Moura, Vera ; Ladeirinha, Ana F. ; Alarcão, Ana ; Gonçalves, Joana ; Abrunhosa, Antero ; Melo, Joana B. ; Carvalho, Lina ; Simões, Sérgio ; Moreira, João N. articleopenAccess
1818-Jun-2021The Enhanced Efficacy of Intracellular Delivery of Doxorubicin/C6-Ceramide Combination Mediated by the F3 Peptide/Nucleolin System Is Supported by the Downregulation of the PI3K/Akt PathwayCruz, Ana F. ; Caleiras, Mariana B. ; Fonseca, Nuno A. ; Gonçalves, Nélio ; Mendes, Vera M. ; Sampaio, Susana F. ; Moura, Vera ; Melo, Joana B. ; Almeida, Ramiro D. ; Manadas, Bruno ; Simões, Sérgio Paulo ; Moreira, João N. articleopenAccess