Ramalho-Santos, João

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Credit Name
Ramalho-Santos, João
 
Name
Santos, João Ramalho
 
 
 
Scopus Author ID
 
Researcher ID
 
Status
UC Researcher
Biography
João Ramalho-Santos is Professor at the Department of Life Sciences, University of Coimbra, Portugal, where he concluded his Ph.D in Cell Biology in 1997. He was a post-doctoral fellow in Reproductive Biology at Oregon Health & Science University USA (1997-2000), a Visiting Scientist at University of Pittsburgh, USA (2003-2006) and a Fulbright Fellow at University of California San Francisco, USA (2009). He currently is the Head of the Biology of Reproduction and Stem Cells Group at the Center for Neuroscience and Cell Biology at the University of Coimbra where he works on the bioenergetics and metabolism of gametes and stem cells, and on Science Communication and Bioethics issues related both to Assisted Reproduction and metabolism, aging and disease.
He is also Director of the Center for Neuroscience and Cell Biology.
He is Associate Editor of the Journals Reproduction and Human Reproduction, reviewer for over 30 journals and 6 agencies (Including FCT, Portugal, MRC, UK, and DFG, Germany). He is a former member of the National Ethics Council for the Life Sciences (CNECV)
h-Factor 47 (Google Scholar), 38 (ISI)
Citations: 8500 (Google Scholar), 5100 (ISI)
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Publications

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Author:  Ramalho-Santos, J.

Results 1-70 of 70 (Search time: 0.008 seconds).

Issue DateTitleAuthor(s)TypeAccess
12001Acrosome components after intracytoplasmic sperm injection: the decondensation frontierRamalho-Santos, João ; Simerly, Calvin R. ; Hewitson, Laura ; Schatten, Gerald articleopenAccess
227-Jun-1997Actividade fusogénica de vírus com envelope lipídico : fusão de membranas promovida pelos vírus influenza e SendaiSantos, João Ramalho de Sousa doctoralThesisembargoedAccess
32012Acute effects of TCDD administration: special emphasis on testicular and sperm mitochondrial functionMota, Paula C. ; Tavares, Renata S. ; Cordeiro, Marília ; Pereira, Susana P. ; Publicover, Stephen J. ; Oliveira, Paulo J. ; Ramalho-Santos, João articleopenAccess
42008Adição de piruvato de sódio e trolox ao diluidor utilizado para congelação de sêmen de garanhões férteis e subférteisSilva, Karen Mascaro Gonçalves da; Gamboa, Sandra Cristina de Oliveira Pinto ; Rodrigues, Ana Sofia ; Santos, João Ramalho ; Guerra, Maria Madalena PessoaarticleopenAccess
52013Anterior positioning of sex chromosomes on the head of human sperm sorted using visible wavelengthsAlçada-Morais, Sofia ; Sousa, Ana Paula ; Paiva, Artur ; Almeida-Santos, Teresa ; Ramalho-Santos, J. articleopenAccess
616-Aug-2019Antioxidant Versus Pro-Apoptotic Effects of Mushroom-Enriched Diets on Mitochondria in Liver DiseaseFontes, Adriana ; Alemany-Pagès, Mireia; Oliveira, Paulo J. ; Ramalho-Santos, João ; Zischka, Hans; Azul, Anabela Marisa articleopenAccess
72018Bridging Health and Social Care with the Citizens – The Case of EIT Health Project “Healiqs4cities” and “Praça Vida+”, in PortugalSá-Moura, Bebiana ; Couceiro, Patrícia ; Catarino, Luis ; Guardado, Diana; Brito, Maja de ; Silva, Bárbara ; Tavares, Rui ; Ramalho-Santos, João ; Teixeira, Ana M. ; Rama, Luís ; Reis, Flávio ; Mota-Pinto, Anabela ; Veríssimo, Manuel ; Gonçalves, Carlos ; Cunha, António ; Malva, João O. articleopenAccess
82018Can we induce spermatogenesis in the domestic cat using an in vitro tissue culture approach?Silva, Andreia F. ; Escada-Rebelo, Sara ; Amaral, Sandra ; Santos Tavares, Renata ; Schlatt, Stefan; Ramalho-Santos, João ; Mota, Paula C. articleopenAccess
92007Characterization of human sperm populations using conventional parameters, surface ubiquitination, and apoptotic markersVarum, Sandra ; Bento, Carla ; Sousa, Ana Paula M. ; Gomes-Santos, Carina S. S. ; Henriques, Paula ; Almeida-Santos, Teresa ; Teodósio, Cristina ; Paiva, Artur ; Ramalho-Santos, João articleopenAccess
102023Comics in Science and Health Communication: Insights From Mutual Collaboration and Framing a Research PracticeTavares, Rui ; Alemany-Pagès, Mireia; Araújo, Sara ; Cohn, Neil; Santos, João Ramalho ; Azul, Anabela Marisa articleopenAccess
11Mar-1993A common mechanism for influenza virus fusion activity and inactivationRamalho-Santos, João ; Nir, Shlomo ; Düzgünes, Nejat ; Carvalho, Arsélio Pato de ; Lima, Maria da Conceição Pedroso de articleopenAccess
122006Comparison between different markers for sperm quality in the cat: Diff-Quik as a simple optical technique to assess changes in the DNA of feline epididymal spermMota, Paula C. ; Ramalho-Santos, João articleopenAccess
13Jun-2016Data on the potential impact of food supplements on the growth of mouse embryonic stem cellsCorreia, Marcelo ; Sousa, Maria I. ; Rodrigues, Ana S. ; Perestrelo, Tânia ; Pereira, Sandro L.; Ribeiro, Marcelo F.; Ramalho-Santos, João articleopenAccess
142015Dichloroacetate, the Pyruvate Dehydrogenase Complex and the Modulation of mESC PluripotencyRodrigues, Ana Sofia ; Correia, Marcelo ; Gomes, Andreia ; Pereira, Sandro L. ; Perestrelo, Tânia ; Sousa, Maria Inês ; Ramalho-Santos, João articleopenAccess
15Jan-2011Differential effects of p,p'-DDE on testis and liver mitochondria: implications for reproductive toxicologyMota, Paula C. ; Cordeiro, Marília ; Pereira, Susana P. ; Oliveira, Paulo J. ; Moreno, António J. ; Ramalho-Santos, João articleopenAccess
1629-Mar-2022Differential Oxygen Exposure Modulates Mesenchymal Stem Cell Metabolism and Proliferation through mTOR SignalingMoniz, Inês ; Ramalho-Santos, João ; Branco, Ana F. articleopenAccess
172015Differentiate or Die: 3-Bromopyruvate and Pluripotency in Mouse Embryonic Stem CellsRodrigues, Ana Sofia ; Pereira, Sandro L. ; Correia, Marcelo ; Gomes, Andreia M. ; Perestrelo, Tânia ; Ramalho-Santos, João articleopenAccess
182013Dioxin-induced acute cardiac mitochondrial oxidative damage and increased activity of ATP-sensitive potassium channels in Wistar ratsPereira, Susana P. ; Pereira, Gonçalo C. ; Pereira, Cláudia V. ; Carvalho, Filipa S. ; Cordeiro, Marília H. ; Mota, Paula C. ; Ramalho-Santos, J. ; Moreno, A. J. M. ; Oliveira, Paulo J. articleopenAccess
192009Dual use of Diff-Quik-like stains for the simultaneous evaluation of human sperm morphology and chromatin statusSousa, Ana Paula M. ; Tavares, Renata S. ; Velez de la Calle, Juan Felipe ; Figueiredo, Helena ; Almeida, Vasco ; Almeida-Santos, Teresa ; Ramalho-Santos, João articleopenAccess
202020Effects of DMSO on the Pluripotency of Cultured Mouse Embryonic Stem Cells (mESCs)Sousa, Maria Inês ; Correia, Bibiana ; Branco, Ana Filipa ; Rodrigues, Ana Sofia ; Ramalho-Santos, João articleopenAccess
212006Effects of hyperglycemia on sperm and testicular cells of Goto-Kakizaki and streptozotocin-treated rat models for diabetesAmaral, Sandra ; Moreno, António J. ; Santos, Maria Sancha ; Seiça, Raquel ; Ramalho-Santos, João articleopenAccess
2217-Jun-2011Energy Metabolism in Human Pluripotent Stem Cells and Their Differentiated CounterpartsVarum, Sandra ; Rodrigues, Ana S. ; Moura, Michelle B. ; Momcilovic, Olga ; Easley, Charles A. ; Ramalho-Santos, João ; Van Houten, Bennett ; Schatten, Gerald articleopenAccess
232013Evaluation of human sperm chromatin status after selection using a modified Diff-Quik stain indicates embryo quality and pregnancy outcomes following in vitro fertilizationTavares, R. S. ; Silva, A. F. ; Lourenço, B. ; Almeida-Santos, T. ; Sousa, A. P. ; Ramalho-Santos, J. articleopenAccess
242006Flow cytometry evaluation of lead and cadmium effects on mouse spermatogenesisOliveira, Helena ; Loureiro, João ; Filipe, Luísa ; Santos, Conceição ; Ramalho-Santos, João ; Sousa, Mário ; Pereira, Maria de Lourdes articleopenAccess
252002Fluorescent probes for monitoring virus fusion kinetics: comparative evaluation of reliabilityNunes-Correia, Isabel ; Eulálio, Ana ; Nir, Shlomo ; Düzgünes, Nejat ; Ramalho-Santos, João ; Lima, Maria C. Pedroso de articleopenAccess
262020Fluorescent probes for the detection of reactive oxygen species in human spermatozoaEscada-Rebelo, Sara ; Mora, Francisca ; Sousa, Ana ; Almeida Santos, Teresa ; Paiva, Artur ; Ramalho-Santos, João articleopenAccess
272008Freeze-dried primate sperm retains early reproductive potential after intracytoplasmic sperm injectionSánchez-Partida, Luis Gabriel ; Simerly, Calvin R. ; Ramalho-Santos, João articleopenAccess
282001Fusion and Infection of Influenza and Sendai Viruses as Modulated by Dextran Sulfate: A Comparative StudyRamalho-Santos, João ; Lima, Maria Pedroso de articleopenAccess
29May-2002Golgi apparatus dynamics during mouse oocyte in vitro maturation: effect of the membrane trafficking inhibitor brefeldin AMoreno, Ricardo D. ; Schatten, Gerald ; Ramalho-Santos, João articleopenAccess
302006Histopathological Effects of Hexavalent Chronium in Mouse KidneyOliveira, H. ; Santos, T. M. ; Ramalho-Santos, J. ; Pereira, M. de Lourdes articleopenAccess
312015I Want More and Better Cells! - An Outreach Project about Stem Cells and Its Impact on the General PopulationAmaral, Sara Varela ; Forte, Teresa ; Ramalho-Santos, João ; Cruz, M. Teresa Girão da articleopenAccess
3210-May-2023In Vitro Evaluation of Biphasic Calcium Phosphate Scaffolds Derived from Cuttlefish Bone Coated with Poly(ester urea) for Bone Tissue RegenerationPereira, Patrícia ; Neto, Ana S.; Rodrigues, Ana Sofia ; Barros, Inês ; Miranda, Catarina O. ; Santos, João Ramalho ; Almeida, Luís Pereira de ; Ferreira, José M. F.; Coelho, Jorge ; Fonseca, Ana C. articleopenAccess
3316-May-2011In Vitro Surfactant Structure-Toxicity Relationships: Implications for Surfactant Use in Sexually Transmitted Infection Prophylaxis and ContraceptionInácio, Ângela S. ; Mesquita, Katia A. ; Baptista, Marta ; Ramalho-Santos, João ; Vaz, Winchil L. C. ; Vieira, Otília V. articleopenAccess
341998The influenza virus hemagglutinin: a model protein in the study of membrane fusionRamalho-Santos, João ; Pedroso de Lima, Maria C. articleopenAccess
352-Dec-2013Inhibition of Mitochondrial Complex III Blocks Neuronal Differentiation and Maintains Embryonic Stem Cell PluripotencySandro, L. Pereira ; Grãos, Mário ; Rodrigues, Ana Sofia ; Anjo, Sandra I. ; Carvalho, Rui A. ; Oliveira, Paulo J. ; Arenas, Ernest ; Ramalho-Santos, João articleopenAccess
3620-Jul-2020Insights from qualitative research on NAFLD awareness with a cohort of T2DM patients: time to go public with insulin resistance?Alemany-Pagès, Mireia; Moura-Ramos, Mariana ; Araújo, Sara ; Macedo, Maria Paula ; Ribeiro, Rogério T. ; do Ó, Dulce; Santos, João Ramalho ; Azul, Anabela Marisa articleopenAccess
3719-Jan-1999Interactions of Influenza Virus with Cultured Cells: Detailed Kinetic Modeling of Binding and EndocytosisNunes-Correia, Isabel ; Ramalho-Santos, João ; Nir, Shlomo ; Lima, Maria C. Pedroso de articleopenAccess
382-Feb-2023Isolation of Extracellular Vesicles from Human Follicular Fluid: Size-Exclusion Chromatography versus UltracentrifugationSoares, Maria ; Pinto, Maria M. ; Nobre, Rui J. ; Almeida, Luís Pereira de ; Rasteiro, Maria da Graça ; Santos, Teresa Almeida ; Santos, João Ramalho ; Sousa, Ana Paula articleopenAccess
391992Kinetic modeling of Sendai virus fusion with PC-12 cells. Effect of pH and temperature on fusion and viral inactivationLima, Maria da Conceição Pedroso de ; Ramalho-Santos, João ; Martins, Maria de Fátima ; Carvalho, Arsélio Pato de ; Bairos, Vasco ; Nir, Shlomo articleopenAccess
402003LIS1 association with dynactin is required for nuclear motility and genomic union in the fertilized mammalian oocytePayne, Christopher ; John, Justin C. St. ; Ramalho-Santos, João ; Schatten, Gerald articleopenAccess
412001Membrane Trafficking Machinery Components Associated with the Mammalian Acrosome during SpermiogenesisRamalho-Santos, João ; Moreno, Ricardo D. ; Wessel, Gary M. ; Chan, Edward K. L. ; Schatten, Gerald articleopenAccess
422013Mitochondria and mammalian reproductionRamalho-Santos, J. ; Amaral, Sandra articleopenAccess
43Jun-2023Mitochondria as biological targets for stem cell and organismal senescenceBranco, Ana ; Moniz, Inês ; Santos, João Ramalho articleopenAccess
442013Mitochondria functionality and sperm qualityAmaral, Alexandra ; Lourenço, Bárbara ; Marques, Mónica ; Ramalho-Santos, J. articleopenAccess
4530-Apr-2009Mitochondrial bioenergetics of testicular cells from the domestic cat (Felis catus)--A model for endangered speciesMota, Paula ; Amaral, Sandra ; Martins, Luís ; Pereira, Maria de Lourdes ; Oliveira, Paulo J. ; Ramalho-Santos, João articleopenAccess
46Mar-2004Mouse genetic corneal disease resulting from transgenic insertional mutagenesisRamalho, J. S. ; Gregory-Evans, K. ; Huxley, C. ; Seabra, M. C. articleopenAccess
47Mar-2022Mushrooms on the plate: Trends towards NAFLD treatment, health improvement and sustainable dietsFontes, Adriana ; Ramalho-Santos, João ; Zischka, Hans; Azul, Anabela Marisa de Jesus Rodrigues articleopenAccess
4827-Sep-2023New Insights on Sperm Function in Male Infertility of Unknown Origin: A Multimodal ApproachPacheco, Rita I. ; Cristo, Maria I. ; Anjo, Sandra I. ; Silva, Andreia F. ; Sousa, Maria Inês ; Santos Tavares, Renata ; Sousa, Ana Paula ; Santos, Teresa Almeida ; Moura-Ramos, Mariana ; Caramelo, Francisco ; Manadas, Bruno ; Santos, João Ramalho ; Amaral, Sandra Gomes articleopenAccess
4923-Mar-2011Not All Sperm Are Equal: Functional Mitochondria Characterize a Subpopulation of Human Sperm with Better Fertilization PotentialSousa, Ana Paula ; Amaral, Alexandra ; Baptista, Marta ; Tavares, Renata ; Caballero Campo, Pedro ; Caballero Peregrín, Pedro ; Freitas, Albertina ; Paiva, Artur ; Almeida-Santos, Teresa ; Ramalho-Santos, João articleopenAccess
502013p,p′-DDE activates CatSper and compromises human sperm function at environmentally relevant concentrationsTavares, Renata S. ; Mansell, Steven ; Barratt, Christopher L. R. ; Wilson, Stuart M. ; Publicover, Stephen J. ; Ramalho-Santos, João articleopenAccess
512009Parabens in male infertility--Is there a mitochondrial connection?Tavares, Renata S. ; Martins, Fátima C. ; Oliveira, Paulo J. ; Ramalho-Santos, João ; Peixoto, Francisco P. articleopenAccess
5227-Sep-1996Partial fusion activity of influenza virus toward liposomes and erythrocyte ghosts is distinct from viral inactivationRamalho-Santos, João ; Lima, Maria C. Pedroso de ; Nir, Shlomo articleopenAccess
538-Aug-2017Pluri-IQ: Quantification of Embryonic Stem Cell Pluripotency through an Image-Based Analysis SoftwarePerestrelo, Tânia ; Chen, Weitong; Correia, Marcelo ; Le, Christopher; Pereira, Sandro ; Rodrigues, Ana S. ; Sousa, Maria I. ; Ramalho-Santos, João ; Wirtz, DenisarticleopenAccess
54May-2020Publicly stressing the role of mitochondria in NAFLD with(in) a sports eventAlemany-Pagès, Mireia; Tavares, Rui Miguel dos Santos ; Varela Amaral, Sara; Barros-Viegas, Ana Teresa ; Oliveira, Paulo J. ; Santos, João Ramalho de Sousa ; Azul, Anabela Marisa de Jesus Rodrigues articleembargoedAccess
552008The quantification of lipid and protein oxidation in stallion spermatozoa and seminal plasma: Seasonal distinctions and correlations with DNA strand breaks, classical seminal parameters and stallion fertilityMorte, Maria Inês ; Rodrigues, Ana Margarida ; Soares, Diana ; Rodrigues, Ana Sofia ; Gamboa, Sandra ; Ramalho-Santos, João articleopenAccess
5616-Mar-1999Role of a Transbilayer pH Gradient in the Membrane Fusion Activity of the Influenza Virus Hemagglutinin: Use of the R18 Assay to Monitor Membrane MergingRamalho-Santos, João ; Lima, Maria C. Pedroso de articleopenAccess
572004The role of target membrane sialic acid residues in the fusion activity of the influenza virus: the effect of two types of ganglioside on the kinetics of membrane mergingRamalho-Santos, João ; Lima, Maria C. Pedroso de articleopenAccess
581-Sep-2008Seminal traits, suitability for semen preservation and fertility in the native Portuguese horse breeds Puro Sangue Lusitano and Sorraia: Implications for stallion classification and assisted reproductionGamboa, Sandra ; Machado-Faria, Manuel ; Ramalho-Santos, João articleopenAccess
591998Sendai Virus Fusion Activity as Modulated by Target Membrane ComponentsNunes-Correia, Isabel ; Ramalho-Santos, João ; Pedroso de Lima, Maria C. articleopenAccess
602004Simultaneous analysis of cytoskeletal patterns and chromosome positioning in human fertilization failuresRamalho-Santos, João ; Amaral, Alexandra ; Brito, Raquel ; Freitas, Mariana ; Santos, Teresa Almeida articleopenAccess
612005SNARE proteins and caveolin-1 in stallion spermatozoa: possible implications for fertilityGamboa, Sandra ; Ramalho-Santos, João articleopenAccess
622000SNAREs in Mammalian Sperm: Possible Implications for FertilizationRamalho-Santos, João ; Moreno, Ricardo D. ; Sutovsky, Peter ; Chan, Anthony Wing-Sang ; Hewitson, Laura ; Wessel, Gary M. ; Simerly, Calvin R. ; Schatten, Gerald articleopenAccess
63Aug-2008Surfactants as microbicides and contraceptive agents: a systematic in vitro studyVieira, Otília V. ; Hartmann, Diego O. ; Cardoso, Carla M. P. ; Oberdoerfer, Daniel ; Baptista, Marta ; Santos, Manuel A. S. ; Almeida, Luis ; Ramalho-Santos, João: articleopenAccess
642008Testicular aging involves mitochondrial dysfunction as well as an increase in UCP2 levels and proton leakAmaral, Sandra ; Mota, Paula ; Rodrigues, Ana Sofia ; Martins, Luís ; Oliveira, Paulo J. ; Ramalho-Santos, João articleopenAccess
652009Testicular mitochondrial alterations in untreated streptozotocin-induced diabetic ratsAmaral, Sandra ; Mota, Paula C. ; Lacerda, Beatriz ; Alves, Marco ; Pereira, Maria de Lourdes ; Oliveira, Paulo J. ; Ramalho-Santos, João articleopenAccess
666-Sep-2021Unhealthy lifestyles, environment, well-being and health capability in rural neighbourhoods: a community-based cross-sectional studyAzul, Anabela Marisa ; Almendra, Ricardo ; Quatorze, Marta; Loureiro, Adriana ; Reis, Flávio ; Tavares, Rui ; Mota-Pinto, Anabela ; Cunha, António ; Rama, Luís ; Malva, João Oliveira ; Santana, Paula ; Santos, João Ramalho ; HeaLIQs4Cities, consortiumarticleopenAccess
679-Aug-2021Using Data Mining to Assist in Predicting Reproductive Outcomes Following Varicocele EmbolizationSousa, Ana Paula ; Santos-Pereira, Judith; Freire, Maria José; Parada, Belmiro ; Almeida Santos, Teresa ; Bernardino, Jorge; Ramalho-Santos, João articleopenAccess
682013UVB irradiation as a tool to assess ROS-induced damage in human spermatozoaAmaral, S. ; Redmann, K. ; Sanchez, V. ; Mallidis, C. ; Ramalho-Santos, J. ; Schlatt, S. articleopenAccess
692002VAMP/synaptobrevin as an acrosomal marker for human spermRamalho-Santos, João ; Terada, Yukihiro ; Schatten, Gerald articleopenAccess
702-Sep-2010Xenografting as a tool to preserve endangered species: outcomes and challenges in model systemsMota, Paula C. ; Ramalho-Santos, João ; Schlatt, StefanarticleopenAccess

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