Ferreira, Lino
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Ferreira, Lino
Name
Ferreira, Lino
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Status
UC Researcher
Biography
I did my graduate work in Jonathan Dordick´s lab at Rensselaer Polytechnic Institute (RPI, Albany, NY) in the development of carbohydrate-based hydrogels, chemically crosslinked, using nonaqueous enzyme technology. I did a first postdoc at the Institute of Biomedical Engineering (Porto, Portugal) for 1 year, specifically at the laboratory of Mário Barbosa (2001 George Winter Award from the European Society of Biomaterials). During that time, I contributed for the development of an intervertebral disc prosthesis. I started in the end of 2004 a second postdoc at MIT in the laboratory of Robert Langer (2002 Charles Stark Draper Prize). The major contributions of my postdoc work was to isolate vascular progenitor cells from human embryonic stem cells (hESCs), to develop synthetic stem cell niches for the self-renewal and vascular differentiation of hESCs, nanomaterials for cell tracking, elastomeric materials, antifungal hydrogels and Gecko-inspired medical adhesives. When I started my laboratory at CNC, University of Coimbra, in October 2007, I established the field of Biomaterials and Stem Cell-Based Therapeutics within the institution. Presently, 29 researchers including 2 Senior Researcher, 10 Postdocs, 8 PhD students, 6 Technicians and 3 Master students form the research group. The research work has been published in Nature Methods, Nature Protocols, Science Translational Medicine, Nature Communications, PNAS, ACS nano, Advanced Materials and Cell Stem Cell. My independent work has been distinguished with several awards in international meetings and with the Crioestaminal Prize, in recognition of the best biomedical basic research project carried out in Portugal in 2008, an ERC grant in 2012 and a ERA Chair grant in 2016. In the last 10 years I attracted around 10 million euros in grants.
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Publications
(All)
Results 1-60 of 60 (Search time: 0.002 seconds).
| Issue Date | Title | Author(s) | Type | Access | |
|---|---|---|---|---|---|
| 1 | 26-Aug-2020 | Advances and challenges in retinoid delivery systems in regenerative and therapeutic medicine | Ferreira, Raquel; Napoli, Joseph; Enver, Tariq; Bernardino, Liliana ; Ferreira, Lino | article | openAccess |
| 2 | 2017 | Anti-Inflammatory Strategy for M2 Microglial Polarization Using Retinoic Acid-Loaded Nanoparticles | Machado-Pereira, Marta; Santos, Tiago ; Ferreira, Lino ; Bernardino, Liliana ; Ferreira, Raquel | article | openAccess |
| 3 | 28-Sep-2017 | Antimicrobial peptide-gold nanoscale therapeutic formulation with high skin regenerative potential | Comune, Michela ; Rai, Akhilesh ; Chereddy, Kiran K; Pinto, Sandra; Aday, Sezin; Ferreira, André F; Zonari, Alessandra ; Blersch, Josephine; Cunha, Rodrigo Pinto Antunes da ; Rodrigues, Ricardo; Lerma, Juan ; Simões, Pedro Nuno ; Préat, Veronique; Ferreira, Lino | article | openAccess |
| 4 | 17-Jul-2023 | Author Correction: Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications | Rebelo, Catarina ; Reis, Tiago ; Guedes, Joana ; Saraiva, Cláudia; Rodrigues, Artur Filipe ; Simões, Susana; Bernardino, Liliana ; Peça, João ; Pinho, Sónia L. C.; Ferreira, Lino | article | openAccess |
| 5 | 23-Jul-2018 | Author Correction: Osmotic modulation of chromatin impacts on efficiency and kinetics of cell fate modulation | Lima, A.; May, G.; Díaz-Colunga, J.; Pedreiro, S.; Paiva, A. ; Ferreira, L. ; Enver, T.; Iborra, F. J.; Neves, R. Pires das | article | openAccess |
| 6 | 21-Oct-2002 | Biocatalytic Polytransesterification of Inulin with Divinyladipate | Ferreira, Lino ; Gil, Maria H. ; Carvalho, Rui ; Geraldes, Carlos F. G. C. ; Kim, Dae-Yun ; Dordick, Jonathan S. | article | openAccess |
| 7 | 2005 | Biocatalytic synthesis of highly ordered degradable dextran-based hydrogels | Ferreira, Lino ; Gil, Maria H. ; Cabrita, António M. S. ; Dordick, Jonathan S. | article | openAccess |
| 8 | 2004 | Biocompatibility of chemoenzymatically derived dextran-acrylate hydrogels | Ferreira, Lino ; Rafael, Ana ; Lamghari, Meriem ; Barbosa, Mario A. ; Gil, Maria H. ; Cabrita, António M. S. ; Dordick, Jonathan S. | article | openAccess |
| 9 | Sep-2017 | Blue light potentiates neurogenesis induced by retinoic acid-loaded responsive nanoparticles | Santos, Tiago ; Ferreira, Raquel ; Quartin, Emanuel ; Boto, Carlos ; Saraiva, Cláudia ; Bragança, José ; Peça, João ; Rodrigues, Cecília ; Ferreira, Lino ; Bernardino, Liliana | article | openAccess |
| 10 | 2013 | Boron nitride nanotube-mediated stimulation of cell co-culture on micro-engineered hydrogels | Ricotti, Leonardo; Fujie, Toshinori; Vazão, Helena ; Ciofani, Gianni; Marotta, Roberto; Brescia, Rosaria; Filippeschi, Carlo; Corradini, Irene; Matteoli, Michela; Mattoli, Virgilio; Ferreira, Lino ; Menciassi, Arianna | article | openAccess |
| 11 | 4-Dec-2018 | Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming | Gomes, Andreia ; Kurochkin, Ilia; Chang, Betty; Daniel, Michael; Law, Kenneth; Satija, Namita; Lachmann, Alexander; Wang, Zichen; Ferreira, Lino ; Ma'ayan, Avi; Chen, Benjamin K.; Papatsenko, Dmitri; Lemischka, Ihor R; Moore, Kateri A.; Pereira, Carlos Filipe | article | openAccess |
| 12 | 2019 | Derivation of Brain Capillary-like Endothelial Cells from Human Pluripotent Stem Cell-Derived Endothelial Progenitor Cells | Praça, Catarina ; Rosa, Susana C. ; Sevin, Emmanuel; Cecchelli, Romeo; Dehouck, Marie-Pierre ; Ferreira, Lino S. | article | openAccess |
| 13 | 18-Feb-2016 | Drug screening on Hutchinson Gilford progeria pluripotent stem cells reveals aminopyrimidines as new modulators of farnesylation | Blondel, S.; Egesipe, A-L; Picardi, P.; Jaskowiak, A-L; Notarnicola, M.; Ragot, J.; Tournois, J.; Le Corf, A.; Brinon, B.; Poydenot, P.; Georges, P.; Navarro, C.; Pitrez, P. R. ; Ferreira, L. ; Bollot, G.; Bauvais, C.; Laustriat, D.; Mejat, A.; De Sandre-Giovannoli, A.; Levy, N.; Bifulco, M.; Peschanski, M.; Nissan, X. | article | openAccess |
| 14 | 2022 | Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications | Rebelo, Catarina ; Reis, Tiago ; Guedes, Joana ; Saraiva, Cláudia; Rodrigues, Artur Filipe ; Simões, Susana; Bernardino, Liliana ; Peça, João ; Pinho, Sónia L. C.; Ferreira, Lino | article | openAccess |
| 15 | 2023 | Engineering graphene-based electrodes for optical neural stimulation | Rodrigues, Artur Filipe ; Tavares, Ana P. M.; Simões, Susana; Silva, Rui P. F. F.; Sobrino, Tomás; Figueiredo, Bruno R.; Sales, Goreti ; Ferreira, Lino | article | embargoedAccess |
| 16 | 2023 | Engineering optical tools for remotely controlled brain stimulation and regeneration | Rodrigues, Artur Filipe ; Rebelo, Catarina; Reis, Tiago ; Simões, Susana; Bernardino, Liliana; Peça, João ; Ferreira, Lino | article; preprint | embargoedAccess |
| 17 | 2002 | Enzymatic synthesis of dextran-containing hydrogels | Ferreira, Lino ; Gil, Maria H. ; Dordick, Jonathan S. | article | openAccess |
| 18 | 11-Mar-2002 | Enzymatic Synthesis of Inulin-Containing Hydrogels | Ferreira, Lino ; Carvalho, Rui ; Gil, Maria H. ; Dordick, Jonathan S. | article | openAccess |
| 19 | 2017 | Erratum: Restoring heart function and electrical integrity: Closing the circuit | Monteiro, Luís Miguel ; Vasques-Nóvoa, Francisco; Ferreira, Lino ; Pinto-do-Ó, Perpétua; Nascimento, Diana Santos | article | openAccess |
| 20 | 2002 | Exquisite Regioselectivity and Increased Transesterification Activity of an Immobilized Bacillus subtilis Protease | Ferreira, Lino ; Ramos, M. A. ; Gil, Maria Helena ; Dordick, Jonathan S. | article | openAccess |
| 21 | 2022 | Extracellular vesicles enriched with an endothelial cell pro-survival microRNA affects skin tissue regeneration | Fernandes, Hugo ; Zonnari, Alessandra; Abreu, Ricardo Cerqueira de ; Aday, Sezin; Barão, Marta ; Albino, Inês ; Lino, Miguel ; Branco, Ana; Seabra, Cátia ; Barata, Tânia; Leal, Ermelindo C. ; Tralhão, José Guilherme; Gonçalves, Lino ; Jong, Alwin de; Peters, Hendrika A.B.; de Vries, Margreet R.; Martins, Paula da Costa ; Quax, Paul H.A.; Ferreira, Lino | article | openAccess |
| 22 | 7-Mar-2019 | Functional characterization of iPSC-derived arterial- and venous-like endothelial cells | Rosa, Susana ; Praça, Catarina ; Pitrez, Patrícia ; Gouveia, Pedro ; Xabier, Aranguren ; Leonardo, Ricotti ; Ferreira, Lino | article | openAccess |
| 23 | 2021 | High-throughput screening of nanoparticles in drug delivery | Tomé, Inês ; Francisco, Vitor ; Fernandes, Hugo ; Ferreira, Lino | article | openAccess |
| 24 | 21-Dec-2020 | A high-throughput screening platform to identify nanocarriers for efficient delivery of RNA-based therapies | Francisco, Vitor ; Rebelo, Catarina; Rodrigues, Artur Filipe ; Blersch, Catarina; Fernandes, Hugo ; Ferreira, Lino | article | openAccess |
| 25 | 8-May-2012 | Histamine modulates microglia function | Ferreira, Raquel ; Santos, Tiago ; Gonçalves, Joana ; Baltazar, Graça ; Ferreira, Lino ; Agasse, Fabienne ; Bernardino, Liliana | article | openAccess |
| 26 | 2008 | Human Embryoid Bodies Containing Nano- and Microparticulate Delivery Vehicles | Ferreira, Lino ; Squier, Trevor ; Park, Hyoungshin ; Choe, Hannah ; Kohane, Daniel S. ; Langer, Robert | article | openAccess |
| 27 | Jan-2011 | Improved Survival, Vascular Differentiation and Wound Healing Potential of Stem Cells Co-Cultured with Endothelial Cells | Pedroso, Dora C. S. ; Tellechea, Ana ; Moura, Liane ; Fidalgo-Carvalho, Isabel ; Duarte, João ; Carvalho, Eugénia ; Ferreira, Lino | article | openAccess |
| 28 | 2021 | Induced pluripotent stem cell-derived vascular networks to screen nano-bio interactions | Estronca, Luís ; Francisco, Vitor ; Pitrez, Patrícia ; Honório, Inês; Carvalho, Lara; Vazão, Helena ; Blersh, Josephine; Rai, Akhilesh ; Nissan, Xavier; Simon, Ulrich; Grãos, Mário ; Saúde, Leonor; Ferreira, Lino | article | openAccess |
| 29 | 21-Oct-2021 | Interindividual heterogeneity affects the outcome of human cardiac tissue decellularization | Tenreiro, Miguel F; Almeida, Henrique V. ; Calmeiro, Tomás; Fortunato, Elvira; Ferreira, Lino ; Alves, Paula M; Serra, Margarida | article | openAccess |
| 30 | 2017 | Intracellular delivery of more than one protein with spatio-temporal control | Lino, Miguel M. ; Simões, Susana ; Pinho, Sónia ; Ferreira, Lino | article | openAccess |
| 31 | 21-Apr-2020 | A light-triggerable formulation to control the stability of pro-angiogenic transcription factor hypoxia inducible factor-1α (HIF-1α) | Blersch, Josephine; Francisco, Vitor ; Rebelo, Catarina; Jiménez-Balsa, Adrián ; Antunes, Helena; Pinto, Sandra; Simões, Susana ; Rai, Akhilesh ; Ferreira, Lino | article | openAccess |
| 32 | 23-May-2018 | Light-triggerable formulations for the intracellular controlled release of biomolecules | Lino, Miguel ; Ferreira, Lino | article | openAccess |
| 33 | 10-Nov-2015 | Lysophosphatidic acid enhances survival of human CD34(+) cells in ischemic conditions | Kostic, Ivana; Fidalgo-Carvalho, Isabel ; Aday, Sezin; Vazão, Helena ; Carvalheiro, Tiago; Grãos, Mário ; Duarte, António; Cardoso, Carla; Gonçalves, Lino ; Carvalho, Lina ; Paiva, Artur ; Ferreira, Lino | article | openAccess |
| 34 | 2018 | MicroRNA-124-loaded nanoparticles increase survival and neuronal differentiation of neural stem cells in vitro but do not contribute to stroke outcome in vivo | Saraiva, Cláudia; Talhada, Daniela; Rai, Akhilesh ; Ferreira, Raquel; Ferreira, Lino ; Bernardino, Liliana ; Ruscher, Karsten | article | openAccess |
| 35 | 5-Jun-2018 | Modulation of Angiogenic Activity by Light-Activatable miRNA-Loaded Nanocarriers | Lino, Miguel M. ; Simões, Susana ; Vilaça, Andreia ; Antunes, Helena ; Zonari, Alessandra ; Ferreira, Lino | article | openAccess |
| 36 | 2018 | A nanoformulation for the preferential accumulation in adult neurogenic niches | Praça, Catarina ; Rai, Akhilesh ; Santos, Tiago ; Cristovão, Ana C.; Pinho, Sonia L.; Cecchelli, Romeo; Dehouck, Marie-Pierre ; Bernardino, Liliana Inácio ; Ferreira, Lino S. | article | openAccess |
| 37 | 13-Apr-2018 | Nanoparticles Conjugated with Photocleavable Linkers for the Intracellular Delivery of Biomolecules | Jiménez-Balsa, Adrián ; Pinto, Sandra ; Quartin, Emanuel ; Lino, Miguel M. ; Francisco, Vitor ; Ferreira, Lino | article | openAccess |
| 38 | 1-Jun-2020 | Native and engineered extracellular vesicles for cardiovascular therapeutics | Abreu, Ricardo Cerqueira de ; Fernandes, Hugo ; Martins, Paula Costa; Sahoo, Susmita; Emanueli, Costanza; Ferreira, Lino | article | openAccess |
| 39 | 16-Sep-2019 | A near infrared light-triggerable modular formulation for the delivery of small biomolecules | Francisco, Vitor ; Lino, Miguel ; Ferreira, Lino | article | openAccess |
| 40 | 8-May-2018 | Osmotic modulation of chromatin impacts on efficiency and kinetics of cell fate modulation | Lima, A. ; May, G.; Díaz-Colunga, J.; Pedreiro, S.; Paiva, A. ; Ferreira, L. ; Enver, T.; Iborra, F. J.; Neves, R. Pires das | article | openAccess |
| 41 | 18-Sep-2020 | Permeability of the blood-brain barrier through the phases of ischaemic stroke and relation with clinical outcome: protocol for a systematic review | Bernardo-Castro, Sara; Donato, Helena ; Ferreira, Lino ; Sargento-Freitas, João | article | openAccess |
| 42 | Feb-2023 | A Polymeric Nanoparticle Formulation for Targeted mRNA Delivery to Fibroblasts | Rodrigues, Artur Filipe ; Rebelo, Catarina ; Simões, Susana ; Paulo, Cristiana ; Pinho, Sónia A. ; Francisco, Vitor ; Ferreira, Lino | article | openAccess |
| 43 | 19-Jun-2019 | A positron-emission tomography (PET)/magnetic resonance imaging (MRI) platform to track in vivo small extracellular vesicles | Banerjee, Arnab; Alves, Vitor; Rondão, Tiago; Sereno, José; Neves, Ângela; Lino, Miguel ; Ribeiro, Andreia; Abrunhosa, Antero ; Ferreira, Lino | article | embargoedAccess |
| 44 | 11-May-2017 | Prolonged intracellular accumulation of light-inducible nanoparticles in leukemia cells allows their remote activation | Boto, Carlos ; Quartin, Emanuel ; Cai, Yijun; Martín-Lorenzo, Alberto; Cenador, María Begoña García; Pinto, Sandra ; Gupta, Rajeev; Enver, Tariq; Sánchez-García, Isidro; Hong, Dengli; Neves, Ricardo Pires das ; Ferreira, Lino | article | openAccess |
| 45 | 1-Feb-2023 | Protein-Nanoparticle Interactions Govern the Interfacial Behavior of Polymeric Nanogels: Study of Protein Corona Formation at the Air/Water Interface | Traldi, Federico; Liu, Pengfei; Albino, Inês ; Ferreira, Lino ; Zarbakhsh, Ali; Resmini, Marina | article | openAccess |
| 46 | 2021 | Re-Use of Caco-2 Monolayers in Permeability Assays—Validation Regarding Cell Monolayer Integrity | Pires, Cristiana L.; Praça, Catarina ; Martins, Patrícia A. T.; Batista de Carvalho, Ana L. M. ; Ferreira, Lino ; Catarro, Maria Paula M. Marques ; Moreno, Maria João | article | openAccess |
| 47 | 2017 | Restoring heart function and electrical integrity: closing the circuit | Monteiro, Luís Miguel ; Vasques-Nóvoa, Francisco; Ferreira, Lino ; Pinto-do-Ó, Perpétua; Nascimento, Diana Santos | article | openAccess |
| 48 | 2015 | Retinoic acid-loaded polymeric nanoparticles induce neuroprotection in a mouse model for Parkinson's disease | Esteves, Marta ; Cristóvão, Ana C.; Saraiva, Tatiana; Rocha, Sandra M.; Baltazar, Graça ; Ferreira, L. ; Bernardino, Liliana | article | openAccess |
| 49 | 2023 | Roadmap on nanomedicine for the central nervous system | Ciofani, Gianni; Campisi, Marco; Mattu, Clara; Kamm, Roger D.; Chiono, Valeria; Raynold, Aji Alex Moothedathu; Freitas, João S. ; Redolfi Riva, Eugenio; Micera, Silvestro; Pucci, Carlotta; Novio, Fernando; Lorenzo, Julia; Ruiz-Molina, Daniel; Sierri, Giulia; Re, Francesca; Wunderlich, Hannah; Kumari, Prachi; Kozielski, Kristen L.; Chami, Mounia; Marino, Attilio; Ferreira, Lino | article | openAccess |
| 50 | 2014 | A stable and reproducible human blood-brain barrier model derived from hematopoietic stem cells | Cecchelli, Romeo; Aday, Sezin; Sevin, Emmanuel; Almeida, Catarina ; Culot, Maxime; Dehouck, Lucie; Coisne, Caroline; Engelhardt, Britta; Dehouck, Marie-Pierre ; Ferreira, Lino | article | openAccess |
| 51 | 2018 | Stem cells as vehicles and targets of nanoparticles | Pinho, Sónia ; Macedo, Maria H; Rebelo, Catarina Araujo Gomes ; Sarmento, Bruno ; Ferreira, Lino | article | openAccess |
| 52 | 2018 | Substrate Topography Modulates Cell Aging on a Progeria Cell Model | Pitrez, Patrícia R. ; Estronca, Luís Miguel Beicinha Branco ; Vazão, Helena ; Egesipe, Anne-Laure; Le Corf, Amélie; Navarro, Claire; Lévy, Nicolas ; De Sandre-Giovannoli, Annachiara; Nissan, Xavier; Ferreira, Lino | article | openAccess |
| 53 | 2005 | Synthesis and characterization of new injectable and degradable dextran-based hydrogels | Maia, João ; Ferreira, Lino ; Carvalho, Rui ; Ramos, Manuel A. ; Gil, Maria H. | article | openAccess |
| 54 | 8-Oct-2007 | Synthesis and Characterization of Photocurable Elastomers from Poly(glycerol-co-sebacate) | Nijst, Christiaan L. E. ; Bruggeman, Joost P. ; Karp, Jeffrey M. ; Ferreira, Lino ; Zumbuehl, Andreas ; Bettinger, Christopher J. ; Langer, Robert | article | openAccess |
| 55 | 2017 | Synthetic microparticles conjugated with VEGF165 improve the survival of endothelial progenitor cells via microRNA-17 inhibition | Aday, Sezin; Zoldan, Janet; Besnier, Marie; Carreto, Laura; Saif, Jaimy; Fernandes, Rui; Santos, Tiago ; Bernardino, Liliana Inácio ; Langer, Robert ; Emanueli, Costanza; Ferreira, Lino | article | openAccess |
| 56 | 7-Aug-2019 | The Kinetics of Small Extracellular Vesicle Delivery Impacts Tissue Regeneration | Antunes, Helena; Cardoso, Renato ; Zonari, Alessandra ; Correia, Joana; Leal, Ermelindo ; Jiménez-Balsa, Adrián ; Lino, Miguel ; Barradas, Ana; Kostic, Ivana; Gomes, Célia ; Karp, Jeffrey; Carvalho, Eugénia ; Ferreira, Lino | article | openAccess |
| 57 | 26-May-2021 | Therapeutic Nanoparticles for the Different Phases of Ischemic Stroke | Bernardo-Castro, Sara; Albino, Inês ; Barrera-Sandoval, Ángela María; Tomatis, Francesca ; Sousa, João André; Martins, Emanuel; Simões, Susana ; Lino, Miguel ; Ferreira, Lino ; Sargento-Freitas, João | article | openAccess |
| 58 | 10-Mar-2011 | Towards the Maturation and Characterization of Smooth Muscle Cells Derived from Human Embryonic Stem Cells | Vazão, Helena ; Neves, Ricardo Pires das ; Grãos, Mário ; Ferreira, Lino | article | openAccess |
| 59 | 2020 | Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13 | Pitrez, Patrícia R. ; Estronca, Luís Miguel Beicinha Branco ; Monteiro, Luís Miguel Marques ; Colell, Guillem; Vazão, Helena ; Santinha, Deolinda da Conceição Ribafeita ; Harhouri, Karim; Thornton, Daniel; Navarro, Claire; Egesipe, Anne-Laure; Carvalho, Tania Rafaela Vale ; Santos, Rodrigo L. dos; Lévy, Nicolas ; Smith, James C.; Magalhães, João Pedro de; Ori, Alessandro; Bernardo, Andreia; De Sandre-Giovannoli, Annachiara; Nissan, Xavier; Rosell, Anna; Ferreira, Lino | article | openAccess |
| 60 | 2019 | What human blood-brain barrier models can tell us about BBB function and drug discovery? | Ferreira, Lino | article | openAccess |